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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HRERFLADKSAPLCGMDIRKSFDQLSSKEKLYTHYVTEASWAGARIIQAQWTPQATDLYDLLILTFSVNGKLADLNALKT
SSGLSEDDWEALIQYTVQVLSNLVNYKTFGFTKIIPRVDAEKFESVVKASSNADQGSALFTKLKQHIYALSPESALFIGK
RKDGHVSNYYLGEPVGDAEVDAIQNVAEKLGVDILNTRVKKNGAGDYTLLVASAKTSPPSVHDFQIDSTPAKLTIEYGDY
ASSLTKVVAALQEAKQYTANDHQSAMIEGYVKSFNSGSIPEHKAASTEWVKDIGPVVESYIGFVETYVDPYGGRAEWEGF
TAIVDKQLSAKYEALVNGAPKLIKSLPWGTDFEVDVFRKPDFTALEVVSFATGGIPAGINIPNYYEVRESTGFKNVSLAN
ILAAKVPNEELTFIHPDDVELYNAWDSRAFELQVANHELLGHGSGKLFQEGADGKLNFDPEKVINPLTGKPITSWYKPGQ
TPDSVLGEVSSSMEECRAETVALYLVSNLDILKIFNYVDKQDIEDIQYITFLLMARAGLRALEFYDPATKKHGQAHMQAR
MGITQYLIQAGIARLELIQDANGELENLYVRVDREKVLSKGKEVVGQLLIELQVRKSTADGTGSRDFYTTLTEPISGWEG
KIRDIVLKKKLPRKIFVQPNTFVVNGEVQLKEYPLTAAGVIESFIERRL

The query sequence (length=689) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5yfb:A 691 689 1.0000 0.9971 1.0000 0.0 5yfb:B, 5yfd:A, 5yfd:B
2 5e2q:A 725 698 0.4253 0.4041 0.4198 2.33e-169 5e33:A, 5e3a:A, 5e3c:A, 5egy:A, 5ehh:A, 3fvy:A, 7oup:A, 3t6b:A, 3t6b:B, 3t6j:A
3 3csk:A 710 723 0.3919 0.3803 0.3734 3.99e-150
4 5na8:A 651 439 0.1713 0.1813 0.2688 7.26e-26 5na6:A, 5na7:A, 5na8:B
5 6eom:A 524 424 0.1466 0.1927 0.2382 3.34e-08
6 5tx1:M 376 181 0.0697 0.1277 0.2652 0.43
7 4k0x:A 243 143 0.0493 0.1399 0.2378 0.80 4jf4:A, 4jf4:B, 4k0w:A, 6n6u:A, 6n6v:A, 6n6x:A, 6n6y:A, 7t7d:A, 7t7e:A, 7t7f:A, 7t7g:A, 5wi3:B, 5wi3:A, 5wi7:A, 5wi7:B, 5wib:A, 5wib:B, 4x55:A, 4x55:B
8 3c4a:A 365 117 0.0464 0.0877 0.2735 1.4
9 8brk:A 135 58 0.0348 0.1778 0.4138 2.2 7ead:A
10 1n4p:B 346 126 0.0522 0.1040 0.2857 2.4 1n4p:D, 1n4p:F, 1n4p:H, 1n4p:J, 1n4p:L, 1n4q:B, 1n4q:D, 1n4q:F, 1n4q:H, 1n4q:J, 1n4q:L, 1n4r:B, 1n4r:D, 1n4r:F, 1n4r:H, 1n4r:J, 1n4r:L, 1n4s:B, 1n4s:D, 1n4s:F, 1n4s:H, 1n4s:L, 1n4s:J, 8rdx:B, 8rdx:D, 8rdx:F, 8rdx:H, 8rdx:J, 8rdx:L, 1s64:B, 1s64:D, 1s64:F, 1s64:H, 1s64:J, 1s64:L, 1tnb:B, 1tnb:D, 1tnb:F, 1tnb:H, 1tnb:J, 1tnb:L, 1tno:B, 1tno:D, 1tno:F, 1tno:H, 1tno:J, 1tno:L, 1tnu:B, 1tnu:D, 1tnu:F, 1tnu:H, 1tnu:J, 1tnu:L, 1tny:B, 1tny:D, 1tny:F, 1tny:H, 1tny:J, 1tny:L, 1tnz:B, 1tnz:D, 1tnz:F, 1tnz:H, 1tnz:J, 1tnz:L
11 6kc0:A 674 46 0.0218 0.0223 0.3261 3.5 6kbd:A
12 7jvd:H 214 72 0.0334 0.1075 0.3194 4.1
13 2a6d:B 219 28 0.0203 0.0639 0.5000 5.7 2a6i:B, 2a6k:H, 4bh7:B, 4bh8:B
14 4iiu:A 243 83 0.0290 0.0823 0.2410 6.2 4iiu:B, 4iiu:C, 4iiu:D, 4iiv:A, 4iiv:B, 4iiv:C, 4iiv:D
15 8oni:H 215 31 0.0218 0.0698 0.4839 7.3 8oni:C, 8onk:H, 8onk:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218