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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HPAEIVAHLQPEIWNKVNRLLVRKAISEYAHEWLLEPQRLGPGETPGFERFRLTLADGAQYDFDAQVMAMRHWRIPPESI
VKTVAGVPAPLDALQFVIEIRDKLGLPVDRLPIYMDEITSTLHGSAYKHGRTTLGAAALARADYQTIETSMIEGHPSFVA
NNGRLGFDAEDYHGYAPEAATPVRLMWLAVHKDNAHFSCLSDMDYDSLMSEELGESAVTDFAARLREQGLHPADYYFMPA
HPWQWFNKLSLAFAPYVAQRKIVCLGYGEEQYLAQQSIRTFFNISRPGKRYVKTSLSILNMGFMRGLSPYYMAGTPAINE
YIHDLISADPWLRANGFRILREVASMGFRNYYYEAAIDTDTPYKKMFSALWRENPLTLIAPGQNLMTMAALLHVDPQGRA
LLPELIQASGLDAGTWLERYVDAYLTPLIHCFYAHDLVFMPHGENVILVIQDGVPVRAFMKDIAEESSILNPQVRLPQAA
QRLAADVPEAYKLLTIFVDVFEGYFRHLTQILVETELMPEHDFWRLVAGRIAAYQQAHPQRLDKYRRYDLFAPDMIHSCL
NRLQLANPNLPNPIACFRPSWL

The query sequence (length=582) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2x0q:A 582 582 1.0000 1.0000 1.0000 0.0 2x0p:A
2 7tgn:B 576 579 0.5223 0.5278 0.5250 0.0 7tgn:A, 7tgn:C, 7tgn:D
3 7tgk:D 593 580 0.5103 0.5008 0.5121 0.0 7tgk:B, 7tgk:E, 7tgk:A, 7tgk:C, 7tgl:A, 7tgl:B, 7tgl:C, 7tgl:D, 7tgl:E, 7tgm:A, 7tgm:B, 7tgm:C, 7tgm:E, 7tgm:D
4 6p63:C 595 567 0.4983 0.4874 0.5115 0.0 6p63:A, 6p63:B, 6p63:D, 6xrc:A, 6xrc:B
5 3to3:B 595 604 0.2595 0.2538 0.2500 5.97e-60
6 7cbb:A 576 353 0.1512 0.1528 0.2493 2.48e-14 7cbb:B
7 5jm8:A 556 419 0.1598 0.1673 0.2220 1.02e-05 5jm8:B, 5jm8:C, 5jm8:D, 5jm8:E, 5jm8:F, 5jm8:G, 5jm8:H
8 2x3j:A 586 199 0.0825 0.0819 0.2412 3.11e-04 2w02:A, 2w02:B, 2w03:A, 2w03:B, 2w04:B, 2x3j:B, 2x3k:A, 2x3k:B
9 2zx6:A 442 114 0.0567 0.0747 0.2895 0.089 1hl9:A, 1hl9:B, 1odu:A, 1odu:B, 2wsp:A, 2wsp:B, 2zwz:A, 2zwz:B, 2zx5:A, 2zx5:B, 2zx6:B, 2zx7:A, 2zx7:B, 2zx8:A, 2zx8:B, 2zx9:A, 2zx9:B, 2zxa:A, 2zxa:B, 2zxb:A, 2zxb:B, 2zxd:A, 2zxd:B
10 7c2x:A 490 171 0.0756 0.0898 0.2573 1.9
11 3rzf:A 541 77 0.0412 0.0444 0.3117 2.8
12 2vma:A 122 63 0.0344 0.1639 0.3175 4.6 3c1q:A, 3c1q:B, 2vma:B, 2vmb:A, 2vmb:B
13 6mvh:D 305 58 0.0344 0.0656 0.3448 6.4
14 4ml8:A 488 58 0.0326 0.0389 0.3276 8.5 4ml8:B, 4ml8:C, 4ml8:D, 4mla:A
15 4mla:B 460 58 0.0326 0.0413 0.3276 8.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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