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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HNFGAMAKEVIEATAKAVNNFWEGLSILEISHRSKEWINVMNETKALMKEVMDIPEGYEILFFGGGASLQFLMVAMNLLN
KKACYLDTGVWASKAIKEAENIGEVKIIGTSKDKNYTYIPEYQIPSDYDYFHITTNNTIYGTEIRKDIESPIPLVADMSS
DILSKPIDISKYSLIYAGAQKNCGAAGVTIVIIKKEILGKVQRKIPIILDYQVHILNNSMYNTPPVISIFTVNQTLKYIK
KIGGLKKIQELNEEKARLLYAEIDRNKIFRGTVRKKDRSIMNVCFVMEEQYKQLENEFSEYALQKGIIGIKGHRSVGGFR
ASIYNAVTIESVQALIKCMHDFEQLH

The query sequence (length=346) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5yb0:B 349 348 0.9942 0.9857 0.9885 0.0 5yb0:A, 5yb0:C, 5yb0:D, 5yb0:E, 5yb0:F, 5yb0:G, 5yb0:H, 5yb0:I, 5yb0:J, 5yb0:K, 5yd2:A, 5yd2:B
2 1bt4:A 361 348 0.4393 0.4211 0.4368 4.16e-100 2c0r:A, 2c0r:B, 1w3u:A
3 4azj:A 360 348 0.4451 0.4278 0.4425 9.40e-100 4azj:B, 4azk:A, 4azk:B, 2bhx:A, 2bhx:B, 2bi1:A, 2bi1:B, 2bi2:A, 2bi2:B, 2bi3:A, 2bi3:B, 2bi5:A, 2bi5:B, 2bi9:A, 2bi9:B, 2bia:A, 2bia:B, 2bie:A, 2bie:B, 2big:A, 2big:B, 1w23:A, 1w23:B
4 6czy:A 362 348 0.4104 0.3923 0.4080 7.21e-92 6czy:B, 6czy:C, 6czy:D, 6czz:A, 6czz:B, 6czz:C, 6czz:D
5 3qbo:B 359 360 0.4249 0.4095 0.4083 1.93e-86 3qbo:A
6 1bjo:A 360 336 0.3960 0.3806 0.4077 3.93e-83 1bjo:B
7 8a5v:E 366 335 0.3931 0.3716 0.4060 2.71e-82 8a5v:C, 8a5v:F, 8a5v:B, 8a5v:A, 8a5v:G, 8a5v:H, 8a5w:D, 8a5w:C, 8a5w:E, 8a5w:F, 8a5w:B, 8a5w:A, 8a5w:H, 3e77:A, 3e77:B
8 7t7j:B 360 336 0.3844 0.3694 0.3958 5.25e-79 7t7j:A
9 6xdk:D 359 342 0.3555 0.3426 0.3596 1.43e-77 6xdk:B, 6xdk:A, 6xdk:C
10 3qm2:B 331 339 0.3815 0.3988 0.3894 4.79e-69 3qm2:A
11 2fyf:A 368 334 0.2139 0.2011 0.2216 6.50e-18 2fyf:B, 3vom:A, 3vom:B
12 3ffr:A 361 275 0.1792 0.1717 0.2255 1.28e-07
13 2dr1:A 381 278 0.1965 0.1785 0.2446 2.44e-06 2dr1:B
14 7kgm:A 512 77 0.0607 0.0410 0.2727 0.18
15 7kgn:A 462 77 0.0607 0.0455 0.2727 0.50
16 8hhl:A 592 67 0.0520 0.0304 0.2687 0.65 8hhm:A
17 5dzt:A 886 108 0.1012 0.0395 0.3241 1.4
18 6v11:C 503 61 0.0520 0.0358 0.2951 1.5 6v11:A, 6v11:B, 6v11:F
19 6v11:E 464 62 0.0520 0.0388 0.2903 2.2
20 6on2:B 524 62 0.0520 0.0344 0.2903 2.3 6on2:C, 6on2:A, 6on2:D, 6on2:E, 6on2:F
21 8w0t:A 398 82 0.0636 0.0553 0.2683 2.4 8w0t:B, 8w0t:C, 8w0t:D, 8w0u:A, 8w0u:B, 8w0u:C, 8w0u:D, 8w0z:A, 8w0z:B, 8w0z:C, 8w0z:D, 8w0z:E, 8w0z:F, 8w0z:G, 8w0z:H
22 8hio:A 567 36 0.0376 0.0229 0.3611 2.9
23 6ntw:A 505 77 0.0578 0.0396 0.2597 2.9
24 3cg3:A 315 156 0.1069 0.1175 0.2372 3.5
25 1ze1:D 284 47 0.0520 0.0634 0.3830 3.6
26 3cg1:A 293 88 0.0665 0.0785 0.2614 4.2 3cg1:B
27 1ze1:A 308 47 0.0520 0.0584 0.3830 4.9 2ab4:A, 1r3e:A, 1ze1:B, 1ze1:C, 1ze2:A
28 3kgw:B 388 224 0.1474 0.1314 0.2277 6.5 3kgw:A, 3kgx:A
29 3ah5:A 215 116 0.0723 0.1163 0.2155 8.5 3ah5:C, 3ah5:B, 3ah5:D, 3ah5:E, 3ah5:F, 3n3y:A, 3n3y:B, 3n3y:C, 3n3y:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218