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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAG
EGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGV
LDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS

The query sequence (length=239) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8apw:A 250 241 0.9958 0.9520 0.9876 4.64e-177 8apt:A, 8apu:A, 8apv:A, 3axz:A, 5d9f:A, 4mcb:A, 4mcb:B, 4mcc:A, 4mcc:B, 4mcd:A, 1uak:A, 1ual:A, 1uam:A, 4ypw:A, 4ypx:A, 4ypy:A, 4ypz:A, 4yq0:A, 4yq1:A, 4yq2:A, 4yq3:A, 4yq4:A, 4yq5:A, 4yq6:A, 4yq7:A, 4yq8:A, 4yq9:A, 4yqa:A, 4yqb:A, 4yqc:A, 4yqd:A, 4yqg:A, 4yqi:A, 4yqj:A, 4yqk:A, 4yql:A, 4yqn:A, 4yqo:A, 4yqp:A, 4yqq:A, 4yqr:A, 4yqs:A, 4yqt:A, 4yvg:A, 4yvh:A, 4yvi:A, 4yvi:B, 4yvj:A, 4yvj:B, 4yvk:A, 4yvk:B
2 1p9p:A 235 236 0.8117 0.8255 0.8220 3.33e-135
3 5wyr:B 248 240 0.6234 0.6008 0.6208 4.01e-111 6afk:A, 6afk:B, 6jki:A, 6jki:B, 6joe:A, 6joe:B, 5wyq:A, 5wyq:B, 5wyr:A, 5zhm:A, 5zhm:B, 5zhn:A, 5zhn:B
4 7mys:A 239 238 0.5397 0.5397 0.5420 6.47e-95 7mys:B
5 4h3z:B 256 244 0.5481 0.5117 0.5369 1.01e-87 4h3y:A, 4h3y:B, 4h3z:A
6 8b1n:B 410 234 0.4435 0.2585 0.4530 1.20e-65
7 8b1n:A 433 234 0.4435 0.2448 0.4530 1.90e-65 8byh:A, 8byh:B, 8ri0:A, 8ri0:B
8 7kff:A 249 234 0.4142 0.3976 0.4231 7.95e-56
9 4ig6:A 223 223 0.3808 0.4081 0.4081 1.86e-52
10 6qrb:A 220 222 0.3849 0.4182 0.4144 2.03e-49 6nw6:A, 6nw6:B, 6nw7:A, 6nw7:B, 6qo2:A, 6qo2:B, 6qo3:A, 6qo3:B, 6qo4:A, 6qo4:B, 6qo6:A, 6qo6:B, 6qoa:A, 6qoa:B, 6qoc:A, 6qoc:B, 6qod:A, 6qod:B, 6qoe:B, 6qof:A, 6qof:B, 6qog:A, 6qoh:A, 6qoh:B, 6qoi:A, 6qoi:B, 6qoj:A, 6qoj:B, 6qok:A, 6qok:B, 6qol:A, 6qol:B, 6qom:A, 6qon:A, 6qon:B, 6qoo:A, 6qoo:B, 6qop:A, 6qop:B, 6qoq:A, 6qoq:B, 6qor:A, 6qor:B, 6qos:A, 6qos:B, 6qot:A, 6qot:B, 6qou:A, 6qou:B, 6qov:A, 6qov:B, 6qow:A, 6qow:B, 6qox:B, 6qqq:A, 6qqq:B, 6qqr:B, 6qqs:A, 6qqt:A, 6qqt:B, 6qqu:A, 6qqu:B, 6qqv:A, 6qqv:B, 6qqw:A, 6qqx:A, 6qqx:B, 6qqy:A, 6qqy:B, 6qqz:A, 6qr0:A, 6qr1:A, 6qr2:A, 6qr3:A, 6qr3:B, 6qr4:A, 6qr4:B, 6qr5:A, 6qr6:A, 6qr6:B, 6qr7:A, 6qr7:B, 6qr8:A, 6qr8:B, 6qr9:A, 6qr9:B, 6qra:A, 6qra:B, 6qrb:B, 6qrc:A, 6qrc:B, 6qrd:A, 6qrd:B, 6qre:A, 6qre:B, 6qrf:A, 6qrg:A, 6qrg:B, 7rez:A, 7rez:B, 7rf0:A, 7rf0:B
11 6w15:A 202 219 0.3724 0.4406 0.4064 1.12e-48
12 5zhk:A 208 219 0.3515 0.4038 0.3836 3.05e-42 6jof:A, 5zhj:A, 5zhl:A
13 8fci:A 197 220 0.3598 0.4365 0.3909 1.89e-41 8fci:B
14 6qqs:B 204 220 0.3598 0.4216 0.3909 8.87e-41 6qqw:B, 6qqz:B, 6qr0:B, 6qr1:B, 6qr2:B, 6qr5:B, 6qrf:B
15 8ee7:A 456 39 0.0586 0.0307 0.3590 1.0 8ee4:A, 8ee4:B, 8ee4:C, 8ee4:D, 8ee4:E, 8ee4:F, 8ee7:B, 8eea:A, 8eea:B, 8eea:C, 8eea:D, 8eea:E, 8eea:F, 8sux:A, 8sux:B, 8sux:C, 8sux:D, 8sux:E, 8sux:F
16 3f3z:A 272 50 0.0837 0.0735 0.4000 5.5
17 8dvv:A 3886 47 0.0586 0.0036 0.2979 7.6 8dvv:B, 8dvv:C, 8dvv:D
18 7dpi:C 292 42 0.0502 0.0411 0.2857 7.6 7dpi:A
19 8i0d:A 446 45 0.0586 0.0314 0.3111 7.8 8i0e:A
20 8dty:A 4004 47 0.0586 0.0035 0.2979 8.0 8dty:B, 8dty:C, 8dty:D
21 6wou:A 3921 47 0.0586 0.0036 0.2979 8.0 6wou:B, 6wou:C, 6wou:D, 6wov:A, 6wov:B, 6wov:C, 6wov:D
22 8dtz:A 4061 47 0.0586 0.0034 0.2979 8.0 8dtz:B, 8dtz:C, 8dtz:D
23 6rtp:B 484 166 0.1548 0.0764 0.2229 8.2 5jsh:B, 5jsk:B, 5jsu:B, 5jsy:B, 5jt1:B, 6ru9:B, 6ruc:B, 2wpn:B, 6z7r:B, 6z7r:D, 6z8j:B, 6z8j:D, 6z8m:B, 6z8o:B, 6z8o:D, 6z9g:B, 6z9g:D, 6z9g:F, 6z9g:H, 6z9o:B, 6za1:B, 3ze6:B, 3ze7:B, 3ze8:B, 3ze9:B, 3zea:B
24 3b0h:A 536 50 0.0669 0.0299 0.3200 9.3 3b0h:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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