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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTPPLGPQDQPDYLNAAVALETSLAPEELLNHTQRIEL
QQGRVRKAERWGPRTLDLDIMLFGNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHTRAFDKLNKW

The query sequence (length=160) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5etl:D 160 159 0.9938 0.9938 1.0000 1.75e-117 6an4:A, 6an6:A, 6an6:B, 1dy3:A, 1eqm:A, 5etk:A, 5etl:A, 5etl:B, 5etl:C, 5etm:A, 5etn:A, 5eto:A, 5etp:A, 1ex8:A, 4f7v:A, 1f9h:A, 1g4c:B, 3hd1:A, 3hd2:A, 1hq2:A, 3hsd:A, 3hsd:B, 3hsg:A, 3ht0:A, 3ilj:A, 3ilo:A, 3ip0:A, 7kdo:A, 7kdr:A, 3kuh:A, 4m5g:A, 4m5h:A, 4m5i:A, 4m5j:A, 4m5k:A, 4m5l:A, 4m5m:A, 4m5n:A, 4m5n:B, 1q0n:A, 1rao:A, 1rb0:A, 1rtz:A, 1ru1:A, 1ru1:B, 1ru2:A, 8sif:A, 1tmj:A, 1tmm:A, 1tmm:B, 3ud5:A, 3ude:A, 3udv:A
2 2qx0:A 159 159 0.6188 0.6226 0.6226 4.80e-70 2qx0:B
3 1cbk:A 160 158 0.5563 0.5563 0.5633 8.56e-64 1cbk:B
4 3qbc:B 161 144 0.3688 0.3665 0.4097 6.64e-34 4ad6:A, 4ad6:B, 4crj:A, 4cwb:A, 4cyu:A, 4cyu:B, 4cyu:C, 4cyu:D, 5etq:A, 5etq:B, 5etr:B, 5etr:A, 5ets:B, 5ets:A, 5ett:B, 5ett:A, 5etv:A, 3qbc:A
5 8sk1:A 162 135 0.3625 0.3580 0.4296 1.44e-32 8sk1:B
6 8sl9:A 422 134 0.3000 0.1137 0.3582 3.24e-22 4pzv:A
7 3mco:A 397 137 0.3000 0.1209 0.3504 4.21e-20 3mcn:B, 3mco:B
8 2bmb:A 513 142 0.2875 0.0897 0.3239 3.15e-16
9 3mcm:A 368 135 0.2687 0.1168 0.3185 4.84e-15 3mcn:A
10 7weg:B 96 24 0.0750 0.1250 0.5000 0.65 7weg:A
11 8jfk:B 1033 34 0.0938 0.0145 0.4412 1.2 8jfk:N, 8jfk:J, 8jfk:F, 8jfl:B, 8jfl:N, 8jfl:F, 8jfl:J, 8xya:B
12 7aor:ae 574 35 0.0813 0.0226 0.3714 1.2
13 8ebu:A 604 89 0.1562 0.0414 0.2809 1.3 8ebt:A, 8ebx:A, 8eby:A
14 7ena:6 652 89 0.1562 0.0383 0.2809 1.4 7ad8:A, 8bvw:0, 8ebs:A, 8ebv:A, 8ebw:A, 7egb:6, 7egc:6, 7enc:6, 8gxq:HH, 8gxs:HH, 5ivw:V, 5iy6:V, 5iy7:V, 5iy8:V, 5iy9:V, 7nvr:7, 7nvv:7, 7nvw:7, 7nvx:7, 7nvy:7, 7nvz:7, 7nw0:7, 6o9l:7, 6ro4:A, 8wak:6, 8wal:6, 8wan:6, 8wao:6, 8wap:6, 8waq:6, 8war:6, 8was:6
15 7lbm:W 574 89 0.1562 0.0436 0.2809 1.4
16 7pc5:A 405 24 0.0750 0.0296 0.5000 2.9
17 7bqo:A 451 147 0.2250 0.0798 0.2449 3.4
18 7sjr:B 802 37 0.0875 0.0175 0.3784 4.2
19 5w5j:B 257 115 0.1938 0.1206 0.2696 5.6 5ar8:A, 5w5j:A
20 6vqw:A 80 58 0.1000 0.2000 0.2759 5.6
21 5xwd:A 611 87 0.1625 0.0426 0.2989 7.3
22 4eyw:B 634 77 0.1250 0.0315 0.2597 8.0 2deb:A, 2deb:B, 4ep9:A, 4eph:A, 4eyw:A, 2fw3:A, 2rcu:A, 2rcu:B
23 6ahf:C 865 49 0.1000 0.0185 0.3265 9.3 6ahf:D, 6ahf:E, 6n8t:A, 6n8t:B, 6n8t:F, 5vy8:C, 5vy8:D, 5vy8:E, 5vy9:A, 5vy9:B, 5vy9:E, 5vy9:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218