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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMSIKVAINGFGRIGRLALRQIEKAHGIEVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDDAIVVNGREIKVFANPN
PEELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVISAPGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPM
AAVLQKEFGVVEGLMTTIHAYTGDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIGLVIPELNGKLDGSAQRVPVAT
GSLTELVSVLERPATKEEINAAMKAASSESYGYNEDQIVSSDVVGIEYGSLFDATQTRVMTVGGKQLVKTVAWYDNEMSY
TCQLVRTLEYFAGK

The query sequence (length=334) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5vmt:B 334 333 0.9970 0.9970 1.0000 0.0 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
2 5vmt:E 293 326 0.8772 1.0000 0.8988 0.0
3 5m6d:A 346 329 0.7126 0.6879 0.7234 1.54e-178 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
4 3lvf:P 338 332 0.6976 0.6893 0.7018 2.38e-175 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
5 5utm:A 345 333 0.7096 0.6870 0.7117 9.25e-175 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
6 6fzi:B 332 331 0.7275 0.7319 0.7341 4.25e-174 6fzi:A, 6fzi:C, 6fzi:D
7 5ld5:C 342 336 0.6347 0.6199 0.6310 1.78e-150 5ld5:A, 5ld5:B, 5ld5:D
8 7www:A 336 334 0.6078 0.6042 0.6078 6.85e-149
9 8hmn:D 340 338 0.5988 0.5882 0.5917 1.96e-145 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
10 7c5o:O 338 331 0.5599 0.5533 0.5650 5.63e-135 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
11 7jwk:C 333 333 0.5359 0.5375 0.5375 2.09e-128 7jwk:A, 7jwk:B, 7jwk:D
12 1hdg:O 332 333 0.5329 0.5361 0.5345 2.44e-124 1hdg:Q
13 2ep7:B 339 345 0.5359 0.5280 0.5188 7.14e-118 2ep7:A
14 3gnq:C 335 333 0.5269 0.5254 0.5285 4.98e-114 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
15 3cmc:O 334 337 0.5299 0.5299 0.5252 5.32e-114 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
16 8br4:A 339 335 0.5449 0.5369 0.5433 1.05e-113 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
17 8hrq:B 336 338 0.5479 0.5446 0.5414 3.65e-112 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
18 3hja:A 334 333 0.5000 0.5000 0.5015 2.33e-111 3hja:B, 3hja:C, 3hja:D
19 6nlx:C 335 332 0.5030 0.5015 0.5060 1.93e-107 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
20 4p8r:A 331 334 0.4850 0.4894 0.4850 6.85e-106 4p8r:B, 4p8r:C, 4p8r:D
21 3doc:A 335 332 0.4940 0.4925 0.4970 1.64e-105 3doc:B, 3doc:C, 3doc:D
22 6ok4:A 334 335 0.4940 0.4940 0.4925 2.56e-105 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
23 1obf:O 335 333 0.5060 0.5045 0.5075 8.11e-105 1obf:P
24 4mvj:B 332 335 0.4790 0.4819 0.4776 3.64e-104 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
25 4lsm:A 331 334 0.4611 0.4653 0.4611 4.24e-104 4lsm:B
26 3l0d:A 332 337 0.4910 0.4940 0.4866 5.69e-102 3l0d:B
27 7bew:A 330 335 0.4731 0.4788 0.4716 1.24e-100 7bex:A
28 2vyn:D 334 335 0.4880 0.4880 0.4866 4.18e-100 2vyv:D
29 7xzg:A 334 335 0.4760 0.4760 0.4746 5.61e-100 7xzg:B, 7xzg:C, 7xzg:D
30 8oha:B 336 336 0.4731 0.4702 0.4702 6.74e-100 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
31 6px2:A 332 341 0.5000 0.5030 0.4897 7.13e-100 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
32 1cer:O 331 331 0.4850 0.4894 0.4894 7.13e-100 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
33 6ghr:B 342 338 0.4940 0.4825 0.4882 1.35e-99 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
34 8de5:A 338 337 0.4611 0.4556 0.4570 5.83e-97
35 3cif:A 338 336 0.4611 0.4556 0.4583 6.09e-97 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
36 1dss:G 333 332 0.4701 0.4715 0.4729 9.74e-97 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
37 6m61:O 336 336 0.4491 0.4464 0.4464 1.12e-95 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
38 1nbo:O 337 340 0.4850 0.4807 0.4765 1.95e-95 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
39 6qun:O 334 329 0.4551 0.4551 0.4620 3.44e-95 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
40 4k9d:A 338 340 0.4760 0.4704 0.4676 5.42e-95 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
41 3gpd:R 334 336 0.4461 0.4461 0.4435 2.28e-94 3gpd:G
42 3sth:C 340 338 0.4431 0.4353 0.4379 3.91e-94 3sth:A, 3sth:B, 3sth:D
43 3e5r:O 336 336 0.4461 0.4435 0.4435 6.12e-94 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
44 3h9e:P 337 338 0.4611 0.4570 0.4556 2.00e-93 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
45 6m5x:O 334 335 0.4491 0.4491 0.4478 4.88e-93 6m5x:R, 6m5x:P, 6m5x:Q
46 3pym:A 332 334 0.4401 0.4428 0.4401 3.69e-92 3pym:B
47 1ywg:O 337 323 0.4311 0.4273 0.4458 7.85e-92 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
48 1a7k:A 358 353 0.4850 0.4525 0.4589 1.70e-90 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
49 3b1j:A 338 341 0.4880 0.4822 0.4780 7.40e-90 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
50 3dmt:A 359 355 0.4820 0.4485 0.4535 1.26e-89 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
51 2i5p:O 309 334 0.4281 0.4628 0.4281 1.98e-87 2i5p:P
52 3k2b:A 337 331 0.4850 0.4807 0.4894 4.55e-86 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
53 7zq3:R 348 342 0.4910 0.4713 0.4795 8.36e-84 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
54 7q54:C 368 341 0.4820 0.4375 0.4721 1.21e-82 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
55 9iil:A 341 343 0.4012 0.3930 0.3907 3.67e-79 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
56 2xf8:M 327 333 0.3802 0.3884 0.3814 1.26e-73 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
57 8jb1:A 468 350 0.3683 0.2628 0.3514 8.34e-57 8jb1:B
58 3hsk:A 358 159 0.1377 0.1285 0.2893 0.21
59 8i7h:A 297 30 0.0449 0.0505 0.5000 0.25 8i7h:B, 8i7h:C, 8i7h:D
60 3aoe:B 424 59 0.0599 0.0472 0.3390 0.46 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
61 5j62:B 209 65 0.0659 0.1053 0.3385 3.5 5j62:A
62 8uw3:A 1265 75 0.0599 0.0158 0.2667 4.5 7n8s:A, 7n94:A, 7n94:B, 8sp5:A, 8sp5:B, 8sp7:A, 8sxt:A, 8sxu:A, 1vyb:B
63 5jwq:A 413 16 0.0329 0.0266 0.6875 7.4 5jwq:C
64 6ido:A 86 25 0.0329 0.1279 0.4400 9.1 6ido:B
65 4g5d:A 283 72 0.0689 0.0813 0.3194 9.1 4g5d:B
66 9fjl:A 168 39 0.0539 0.1071 0.4615 9.7
67 2czc:A 334 37 0.0329 0.0329 0.2973 9.9 2czc:B, 2czc:C, 2czc:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218