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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMRHRTLSSSPALWASIPCPRSELRLDLVLASGQSFRWKEQSPAHWSGVLADQVWTLTQTEDQLYCTVYRGDDSQVSRPT
LEELETLHKYFQLDVSLAQLYSHWASVDSHFQRVAQKFQGVRLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPR
LIQLDDVTYHGFPNLHALAGPEAETHLRKLGLGYRARYVRASAKAILEEQGGPAWLQQLRVAPYEEAHKALCTLPGVGAK
VADCICLMALDKPQAVPVDVHVWQIAHRDYGWHPKTPSPLANKELGNFFRNLWGPYAGWAQAVLFSADLRQ

The query sequence (length=311) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8bvx:A 316 316 1.0000 0.9842 0.9842 0.0 7ayz:AAA, 7ayz:BBB, 7ayz:CCC, 7az0:AAA, 7az0:BBB, 8bq7:A, 8cex:A, 8cey:A, 8cey:B, 8cey:C, 6g3y:A, 6g3y:B, 6g3y:C, 6g40:A, 6g40:B, 6g40:C, 7pz1:AAA, 7qel:AAA, 7qel:BBB, 7qel:CCC, 7z3y:AAA, 7z5b:A, 7z5b:B, 7z5b:C, 7z5r:A, 7z5r:B, 7z5r:C, 7zc7:A, 7zc7:B, 7zc7:C, 7zg3:A, 7zg3:B, 7zg3:C
2 2xhi:A 316 315 0.8617 0.8481 0.8508 0.0 7ayy:AAA, 7ayy:BBB, 7ayy:CCC, 7ayy:DDD, 7ayy:EEE, 1ebm:A, 1fn7:A, 1hu0:A, 2i5w:A, 3ih7:A, 3ktu:A, 1lwv:A, 1lww:A, 1lwy:A, 1m3h:A, 1m3q:A, 1n39:A, 1n3a:A, 1n3c:A, 2nob:A, 2noe:A, 2nof:A, 2noh:A, 2noi:A, 2nol:A, 2noz:A, 6rlw:AAA, 6rlw:BBB, 6rlw:CCC, 6rlw:DDD, 6rlw:EEE, 6w0m:A, 6w0r:A, 6w13:A, 1yqk:A, 1yql:A, 1yqm:A, 1yqr:A
3 4ejy:A 289 284 0.2733 0.2941 0.2993 5.28e-30 4ejy:B, 4ejz:A, 4ejz:B
4 3f10:A 292 283 0.2476 0.2637 0.2721 2.00e-27 3i0w:A, 3i0x:A
5 7yhq:A 393 64 0.0804 0.0636 0.3906 0.001
6 4uob:A 242 100 0.1125 0.1446 0.3500 0.002 8a5g:A
7 8a5c:A 237 53 0.0707 0.0928 0.4151 0.003 8a5f:A, 4unf:A
8 2abk:A 211 87 0.0740 0.1090 0.2644 0.039
9 1kea:A 217 106 0.0868 0.1244 0.2547 0.054
10 7yhp:A 374 57 0.0675 0.0561 0.3684 0.13 7yho:A
11 7rds:A 232 158 0.1318 0.1767 0.2595 0.29 7rdt:A
12 1kg5:A 225 110 0.1061 0.1467 0.3000 0.99 1kg2:A, 1kg3:A, 1kg4:A, 1kg6:A, 1kg7:A, 1kqj:A, 1mud:A, 1mun:A, 1muy:A, 1wef:A, 1weg:A, 1wei:A
13 3ogd:A 288 142 0.1190 0.1285 0.2606 1.3 3cvs:A, 3cvs:B, 3cvs:C, 3cvs:D, 3cvt:A, 3cvt:B, 3cvt:C, 3cvt:D, 3cw7:A, 3cw7:B, 3cw7:C, 3cw7:D, 3cwa:A, 3cwa:B, 3cwa:C, 3cwa:D, 3cws:A, 3cws:B, 3cws:C, 3cws:D, 3cwt:A, 3cwt:B, 3cwt:C, 3cwt:D, 3cwu:A, 3cwu:B, 3cwu:C, 3cwu:D, 3d4v:A, 3d4v:B, 3d4v:C, 3d4v:D, 1diz:B, 1diz:A, 3oh6:A, 3oh9:A, 1pvs:A, 1pvs:B
14 8wa0:B 973 39 0.0354 0.0113 0.2821 1.8 8w9z:B
15 8wa1:B 998 39 0.0354 0.0110 0.2821 1.8
16 7pg7:D 329 52 0.0611 0.0578 0.3654 2.3
17 5wgb:A 291 52 0.0579 0.0619 0.3462 3.2
18 6vaa:B 1153 47 0.0450 0.0121 0.2979 3.6
19 8h7g:K 352 86 0.0772 0.0682 0.2791 3.8
20 8a22:Bi 282 65 0.0579 0.0638 0.2769 4.6 8apn:Bi, 8apo:Bi
21 6bpn:A 656 30 0.0386 0.0183 0.4000 4.7
22 1p6v:A 125 52 0.0482 0.1200 0.2885 7.6 1p6v:C
23 6bie:B 97 38 0.0386 0.1237 0.3158 9.7 6owx:B, 5wnw:B, 5wo1:A, 5wo1:B, 5wo2:B, 5wo3:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218