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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMPRVLVTGALGQIGTDLSLALRDKFGADSVLVSDVVEPGAKHPLAGLKGVEKLDCLDSNGFEKLVKEFKPTWMYHLPAI
MSVRGEAEPDLAMDINVNTTRYALELARKYNIRIFIPSTIAAFGDKCGKTMTKDDTIMNPSTVYGVTKVYTELLGTWYRQ
KYGVDFRSVRLPGIISAATLPGGGATDYAIHMYHSALLQKKCVCPVLPYESLPMMYMPDTLNSLVKIMEAPLEKLTRTVY
NITGFSFSPSELRFSIERCTDRTIEVEYVEGPAQKIANSWPDSLDDSNARNDWGHQVKYDIDMMSEDMLRQIPILHGLPS
L

The query sequence (length=321) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5k4w:C 321 321 1.0000 1.0000 1.0000 0.0 5k4q:A, 5k4q:B, 5k4q:C, 5k4q:D, 5k4q:E, 5k4q:F, 5k4u:A, 5k4u:C, 5k4v:A, 5k4v:C, 5k4w:A, 5k4y:A, 5k4y:B, 5k4y:C, 5k4y:D, 5k4y:E, 5k4y:F, 5k50:A, 5k50:C, 5k50:E, 5k50:G, 5k50:I, 5k50:J, 5lc1:A, 5lc1:B, 5lc1:C, 5lc1:D, 5lc1:E, 5lc1:F
2 8gjb:A 320 320 0.7259 0.7281 0.7281 8.69e-180 8gjb:B
3 7cgv:A 310 313 0.4548 0.4710 0.4665 3.64e-91 7cgv:B, 7cgv:C, 7cgv:D
4 5z75:A 306 312 0.4424 0.4641 0.4551 1.30e-89 5z75:B, 5z75:D
5 6jyg:D 307 309 0.4143 0.4332 0.4304 6.46e-86 6jyg:A, 6jyg:B, 6jyg:C, 6jyg:E, 6jyg:F
6 3a1n:A 315 311 0.4050 0.4127 0.4180 1.25e-79 3a1n:B, 3a4v:A, 3a4v:B, 3a9w:A, 3a9w:B, 3ajr:A, 3ajr:B
7 5y1f:A 311 317 0.4143 0.4277 0.4196 1.12e-78 5y1e:A, 5y1g:A
8 7epr:B 310 312 0.4081 0.4226 0.4199 1.69e-77 7epr:A, 7epr:C, 7epr:D
9 7eps:A 310 312 0.3988 0.4129 0.4103 1.78e-77 7eps:B, 7eps:C, 7eps:D, 3wmx:A, 3wmx:B, 3wmx:C, 3wmx:D
10 4yr9:A 308 308 0.3988 0.4156 0.4156 1.54e-74 4yr9:B, 4yr9:C, 4yr9:D, 4yr9:E, 4yr9:F
11 2yy7:A 312 312 0.3832 0.3942 0.3942 8.28e-71 2yy7:B
12 3wmw:B 278 312 0.3614 0.4173 0.3718 3.73e-65 3wmw:A
13 4yrb:C 249 307 0.3427 0.4418 0.3583 1.17e-53 4yrb:A, 4yrb:D, 4yrb:E
14 4yrb:B 215 307 0.3053 0.4558 0.3192 2.73e-41 4yrb:F
15 2p5u:A 311 192 0.1713 0.1768 0.2865 1.19e-08 2p5u:B, 2p5u:C, 2p5u:D, 2p5y:A
16 2ggs:A 273 290 0.2336 0.2747 0.2586 1.11e-07 2ggs:B
17 4zrn:A 309 189 0.1526 0.1586 0.2593 1.84e-07 4zrm:A, 4zrm:B, 4zrn:B
18 2pk3:A 309 219 0.1620 0.1683 0.2374 5.08e-07 2pk3:B
19 6dnt:A 310 173 0.1402 0.1452 0.2601 1.01e-06
20 1orr:A 338 132 0.1184 0.1124 0.2879 7.59e-06 1orr:B, 1orr:C, 1orr:D
21 6pnl:A 336 183 0.1402 0.1339 0.2459 8.57e-06 6pmh:A
22 6zll:A 321 257 0.1994 0.1994 0.2490 1.30e-05 6zl6:A, 6zl6:B, 6zla:A, 6zla:B, 6zla:C, 6zla:D, 6zld:A, 6zld:B, 6zlj:A, 6zlj:B, 6zlk:A, 6zlk:B, 6zlk:C, 6zlk:D, 6zll:B, 6zll:C, 6zll:D
23 3ehe:A 290 180 0.1464 0.1621 0.2611 5.61e-05 3ehe:B
24 6vlo:A 319 182 0.1464 0.1473 0.2582 5.65e-05 6vlo:B, 6vlo:C, 6vlo:D
25 1z45:A 674 161 0.1495 0.0712 0.2981 1.34e-04
26 7yst:A 312 206 0.1713 0.1763 0.2670 1.49e-04 7ys8:A, 7ys8:B, 7ys9:A, 7ys9:B, 7ysa:A, 7ysa:B, 7ysm:A, 7ysm:B, 7yst:B, 7ysy:A, 7ysy:B, 7yt0:A, 7yt0:B
27 2c20:A 329 181 0.1340 0.1307 0.2376 2.01e-04 2c20:B, 2c20:C, 2c20:D, 2c20:E, 2c20:F
28 5u4q:A 321 238 0.1713 0.1713 0.2311 2.22e-04
29 8v4h:B 342 249 0.1838 0.1725 0.2369 2.68e-04 8v4g:A, 8v4g:B, 8v4h:A
30 1keu:A 361 186 0.1371 0.1219 0.2366 3.19e-04 1g1a:A, 1g1a:B, 1g1a:C, 1g1a:D, 1keu:B, 1kew:A, 1kew:B
31 5u4q:B 304 235 0.1651 0.1743 0.2255 3.97e-04
32 5in4:A 355 196 0.1558 0.1408 0.2551 4.32e-04 6gpj:A, 6gpj:B, 6gpj:D, 6gpj:C, 6gpk:A, 6gpk:B, 6gpk:C, 6gpk:D, 6gpl:B, 6gpl:E, 6gpl:C, 6gpl:D, 5in4:B, 5in4:C, 5in4:D, 5in5:A, 5in5:B, 5in5:C, 5in5:D, 6q94:B, 6q94:A, 6q94:C, 6q94:E, 6q94:D, 6q94:F, 6q94:G, 6q94:H, 1t2a:A, 1t2a:D, 1t2a:B, 1t2a:C
33 6wj9:B 308 289 0.1994 0.2078 0.2215 7.65e-04 6wj9:A, 6wja:A, 6wja:B, 6wjb:A, 6wjb:B
34 3aw9:A 304 174 0.1464 0.1546 0.2701 0.001 3aw9:B, 3aw9:C, 3icp:A, 3ko8:A
35 2b69:A 312 238 0.1745 0.1795 0.2353 0.001 4gll:A, 4gll:B
36 1bxk:B 344 180 0.1402 0.1308 0.2500 0.001 1bxk:A
37 3vps:A 303 315 0.2274 0.2409 0.2317 0.003 3vps:B
38 1vl0:A 281 153 0.1308 0.1495 0.2745 0.003 1vl0:B, 1vl0:C
39 6k0g:A 335 163 0.1371 0.1313 0.2699 0.004 6k0h:A, 6k0i:A
40 1wvg:A 352 273 0.2056 0.1875 0.2418 0.004 1wvg:B
41 8du1:A 361 283 0.1869 0.1662 0.2120 0.005 8du1:B, 8du1:C, 8du1:D
42 8wov:B 341 158 0.1277 0.1202 0.2595 0.011 8wop:A, 8wop:B, 8wov:A, 8wow:A, 8wow:B
43 4e5y:C 290 173 0.1277 0.1414 0.2370 0.016
44 5bju:A 340 156 0.1246 0.1176 0.2564 0.020 5bju:B, 5bjv:A, 5bjv:B, 5bjw:A, 5bjw:B, 5bjx:A, 5bjx:B, 5bjy:A, 5bjy:B
45 2ydx:A 312 151 0.1308 0.1346 0.2781 0.028 2ydx:C, 2ydx:B, 2ydx:D, 2ydx:E
46 2pzm:A 316 155 0.1246 0.1266 0.2581 0.038 2pzk:A, 2pzk:B, 2pzl:A, 2pzl:B, 2pzm:B
47 1eq2:A 273 159 0.1246 0.1465 0.2516 0.039 1eq2:C
48 3sc6:D 283 182 0.1402 0.1590 0.2473 0.051 3sc6:A, 3sc6:B, 3sc6:C, 3sc6:E, 3sc6:F
49 1ker:B 347 187 0.1526 0.1412 0.2620 0.060 1kep:A, 1kep:B, 1ker:A, 1ket:A, 1ket:B, 1oc2:A, 1oc2:B
50 1rkx:C 351 266 0.2025 0.1852 0.2444 0.085 1rkx:A, 1rkx:B, 1rkx:D
51 2x6t:G 308 159 0.1215 0.1266 0.2453 0.091 1eq2:B, 1eq2:D, 1eq2:E, 1eq2:F, 1eq2:G, 1eq2:H, 1eq2:I, 1eq2:J, 2x6t:A, 2x6t:B, 2x6t:C, 2x6t:D, 2x6t:E, 2x6t:F, 2x6t:H, 2x6t:I, 2x6t:J, 2x86:A, 2x86:B, 2x86:C, 2x86:D, 2x86:E, 2x86:F, 2x86:G, 2x86:H, 2x86:I, 2x86:J, 2x86:K, 2x86:L, 2x86:M, 2x86:N, 2x86:O, 2x86:P, 2x86:Q, 2x86:R, 2x86:S, 2x86:T
52 3rfv:A 265 173 0.1464 0.1774 0.2717 0.12 3rfv:B, 3rfv:C, 3rfx:A, 3rfx:B, 3rfx:C
53 1rpn:D 322 167 0.1246 0.1242 0.2395 0.15 1rpn:A, 1rpn:B, 1rpn:C
54 6vo6:D 311 161 0.1153 0.1190 0.2298 0.16 6vo6:A, 6vo6:B, 6vo6:C, 6vo8:A, 6vo8:B
55 1a9y:A 338 167 0.1277 0.1213 0.2455 0.19 1a9z:A, 5gy7:A, 5gy7:B, 1kvq:A, 1kvr:A, 1kvs:A, 1kvt:A, 1kvu:A, 1lrj:A, 1lrk:A, 1lrl:A, 1nah:A, 1nai:A, 1uda:A, 1udb:A, 1udc:A, 2udp:A, 2udp:B, 1xel:A
56 1sb8:A 341 189 0.1495 0.1408 0.2540 0.25 1sb9:A
57 7kn1:A 336 165 0.1340 0.1280 0.2606 0.27 7kn1:B
58 2q1w:A 300 189 0.1402 0.1500 0.2381 0.32 2q1w:B, 2q1w:C
59 4twr:A 325 278 0.2181 0.2154 0.2518 0.47 4wok:A
60 1z7e:D 644 183 0.1526 0.0761 0.2678 0.52 2bln:A, 2bln:B, 5j63:A, 5j63:B, 5j63:C, 5j63:D, 1z7e:A, 1z7e:B, 1z7e:C, 1z7e:E, 1z7e:F
61 4m55:E 164 121 0.1028 0.2012 0.2727 0.54
62 1qo8:A 564 125 0.0966 0.0550 0.2480 0.56 1qo8:D
63 4lk3:B 274 131 0.1121 0.1314 0.2748 0.62 4lk3:A, 4lk3:C, 4lk3:D, 4lk3:E, 4lk3:F, 4m55:A, 4m55:B, 4m55:C, 4m55:D
64 6kv9:A 299 163 0.1464 0.1572 0.2883 0.81 6kvc:A
65 6aqz:A 334 136 0.0872 0.0838 0.2059 1.0 6aqz:B, 6aqz:C, 6aqz:E, 6aqz:F
66 4lis:A 364 162 0.1402 0.1236 0.2778 1.8 4lis:B, 4lis:C
67 8fti:A 737 60 0.0623 0.0271 0.3333 2.2 7vti:A
68 1i3k:A 347 132 0.0966 0.0893 0.2348 4.9 1ek5:A, 1ek6:A, 1ek6:B, 1hzj:A, 1hzj:B, 1i3k:B, 1i3l:A, 1i3l:B, 1i3m:A, 1i3m:B, 1i3n:A, 1i3n:B
69 3h4l:B 344 94 0.0779 0.0727 0.2660 7.0 3h4l:A
70 5uzh:A 345 179 0.1371 0.1275 0.2458 7.5
71 5nue:B 332 49 0.0654 0.0633 0.4286 8.0 5nue:A, 5nue:C, 5nuf:A, 5nuf:B, 5nuf:C
72 1yhu:B 144 51 0.0436 0.0972 0.2745 8.3 1yhu:F, 1yhu:J, 1yhu:N, 1yhu:R, 1yhu:V
73 8q6o:D 256 78 0.0685 0.0859 0.2821 9.6 8q6o:5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218