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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMPRFYLPENLSVGQTVDLPDNIVRHLNVLRVRPNENITLFDGKGKAHTARLTVLEKHRAEAEILHEDTTDNESPLNITL
IQSISSGDRMDFTLQKSVELGVTAIQPVISERCIVRAAKRLARWQEIVISACEQSGRNTVPPVLPIIGYREALDKMPSEN
TKLIMSINRACKLGDIRHPSGAIVFMVGPEGGWTEQEEQQAFEAGFQAVTLGKRILRTETAPLAAIAAMQTLWGDFT

The query sequence (length=237) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5vm8:B 237 237 1.0000 1.0000 1.0000 4.34e-179
2 5o96:D 243 241 0.3671 0.3580 0.3610 3.83e-44 5o96:A, 5o96:B, 5o96:C, 5o96:E, 5o96:F, 5o96:G, 5o96:H
3 2cx8:A 225 213 0.2827 0.2978 0.3146 2.60e-25 2cx8:B, 2z0y:A, 2z0y:B
4 3kw2:A 240 237 0.2954 0.2917 0.2954 1.00e-22 3kw2:B
5 2egv:A 229 236 0.2996 0.3100 0.3008 2.17e-20 2egv:B, 2egw:A, 2egw:B
6 4gxb:A 263 133 0.1097 0.0989 0.1955 0.13 4tkn:A, 4tkn:B, 4tkn:C
7 6sga:FC 311 90 0.1055 0.0804 0.2778 0.55 6sgb:FC
8 5azb:A 284 27 0.0549 0.0458 0.4815 0.74 5azc:A
9 6sga:FB 377 90 0.1055 0.0663 0.2778 0.96 6sgb:FB
10 1vc4:B 254 56 0.0717 0.0669 0.3036 2.1
11 3eue:A 295 47 0.0633 0.0508 0.3191 2.6 3euf:A, 3euf:B, 3euf:C, 3euf:D, 3nbq:A, 3nbq:B, 3nbq:C, 3nbq:D
12 6ixj:A 251 38 0.0549 0.0518 0.3421 9.2 6ixj:B, 6ixj:C, 6ixj:D, 6ixj:E, 6ixj:F, 6ixj:G, 6ixj:H, 6ixj:I, 6ixj:J, 6ixj:K, 6ixj:L
13 6ok4:A 334 48 0.0464 0.0329 0.2292 9.2 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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