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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNSPERIITLTGPTNAIFKAFAMIIDKLEEDINSSW

The query sequence (length=76) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3vke:A 76 76 1.0000 1.0000 1.0000 1.97e-50 2axy:B, 2axy:D, 2pqu:C, 2pqu:B, 2py9:B, 2py9:C, 3vke:B, 3vke:C, 3vke:D, 1ztg:A, 1ztg:D, 1ztg:B, 1ztg:C
2 2axy:A 72 68 0.8421 0.8889 0.9412 3.22e-41 2axy:C, 2pqu:A, 2py9:A
3 8coo:A 191 71 0.3158 0.1257 0.3380 3.10e-08 2n8l:A, 2n8m:A
4 2anr:A 155 67 0.3158 0.1548 0.3582 4.19e-08 2ann:A
5 2anr:A 155 71 0.2632 0.1290 0.2817 3.58e-04 2ann:A
6 6y2c:B 84 57 0.3026 0.2738 0.4035 4.91e-08
7 1zzi:A 82 71 0.3553 0.3293 0.3803 5.07e-08 7cre:A, 1j5k:A, 1zzi:B, 1zzj:A, 1zzj:B
8 1j4w:A 145 70 0.3289 0.1724 0.3571 1.38e-07 6y2c:A
9 1j4w:A 145 61 0.2763 0.1448 0.3443 0.002 6y2c:A
10 7yey:A 162 73 0.3158 0.1481 0.3288 3.35e-06 7vkl:A
11 7yey:A 162 76 0.3158 0.1481 0.3158 2.47e-04 7vkl:A
12 4b8t:A 106 58 0.2763 0.1981 0.3621 4.69e-06
13 2p2r:A 73 61 0.3026 0.3151 0.3770 1.97e-04
14 3j9z:SC 232 48 0.2500 0.0819 0.3958 0.005 4a2i:C, 8a3l:C, 7abz:h, 7ac7:h, 7acj:h, 7acr:h, 4adv:C, 5afi:c, 7af3:C, 7af5:C, 7af8:C, 7afa:C, 7afd:C, 7afh:C, 7afk:C, 7afn:C, 8akn:D, 8am9:D, 6awb:F, 6awc:F, 6awd:F, 9ax7:C, 9ax8:c, 8aye:C, 8b0x:C, 7b5k:c, 8b7y:E, 8bf7:g, 8bge:g, 8bgh:g, 8bh4:g, 8bhj:g, 8bhl:g, 8bhn:g, 8bhp:g, 8bil:g, 8bim:g, 7boe:C, 7boh:C, 6bu8:C, 6by1:AC, 6by1:BC, 6c4i:c, 8ca7:C, 8caz:C, 8cf1:C, 8cf8:C, 8cgi:C, 8cgj:C, 9cg5:C, 9cg6:C, 9cg7:C, 7cpj:c, 7d6z:j, 7d80:D, 6dnc:PA, 8eiu:C, 8ekc:c, 8emm:C, 6enf:c, 6enj:c, 6enu:c, 8eyq:C, 8eyt:F, 9fbv:C, 8fiz:AG, 8fto:C, 8fzd:c, 8fze:c, 8fzf:c, 8fzg:c, 8fzh:c, 8fzi:c, 8fzj:c, 8g2u:b, 8g31:x, 8g34:x, 8g38:x, 8g6w:C, 8g7p:c, 8g7q:c, 8g7r:c, 8g7s:c, 8ghu:c, 6gwt:c, 6gxm:c, 6gxn:c, 6gxo:c, 6gxp:c, 6h4n:c, 5h5u:j, 6h58:c, 6h58:cc, 6hrm:h, 8hsp:C, 8htz:C, 8hu1:C, 6i7v:AC, 6i7v:BC, 8ifb:C, 8ifc:C, 5iqr:h, 5it8:AC, 5it8:BC, 5j5b:AC, 5j5b:BC, 5j7l:AC, 5j7l:BC, 5j88:AC, 5j88:BC, 5j8a:AC, 5j8a:BC, 3j9y:c, 5j91:AC, 5j91:BC, 3ja1:SC, 3jbu:C, 3jbv:C, 3jcd:c, 3jce:c, 3jcj:h, 3jcn:c, 5jc9:AC, 5jc9:BC, 7jss:H, 7jsw:H, 7jsz:H, 8jsg:h, 5jte:AC, 7jt1:H, 7jt2:H, 7jt3:H, 5ju8:AC, 7k00:C, 8k3o:C, 8k4e:C, 7k50:H, 7k51:H, 7k52:H, 7k53:H, 7k54:H, 7k55:H, 5kcr:1c, 5kcs:1c, 5kps:8, 5kpv:7, 5kpw:7, 5kpx:7, 5l3p:c, 6lkq:B, 7lv0:H, 5lza:c, 5lzb:c, 5lzc:c, 5lzd:c, 5lze:c, 5lzf:c, 7m5d:h, 5mdv:h, 5mdw:h, 5mdy:h, 5mdz:h, 5me0:C, 5me1:C, 5mgp:c, 5my1:C, 7n1p:SC, 7n2c:SC, 7n2u:SC, 7n2v:SC, 7n30:SC, 7n31:SC, 7nar:C, 7nat:C, 7nau:C, 7nav:C, 7nax:C, 7nbu:C, 5no4:C, 5np6:F, 6nqb:C, 7nso:c, 7nsp:c, 7nsq:c, 5nwy:2, 7nwt:h, 7nww:g, 7o19:AC, 7o1a:AC, 7o1c:AC, 5o2r:c, 6o7k:h, 6o9j:c, 6o9k:c, 7oe0:C, 7oe1:C, 6ofx:H, 6og7:H, 6ogf:H, 6ogg:H, 6ogi:H, 7oif:g, 7oig:g, 7oii:g, 7oiz:C, 7oj0:C, 6om6:h, 6ore:h, 6orl:h, 6osk:h, 6osq:h, 6ost:h, 6ot3:h, 7ot5:g, 7otc:c, 6ouo:h, 8p16:h, 8p17:h, 8p18:h, 7p3k:C, 8peg:C, 8phj:C, 7pjs:c, 7pjt:c, 7pju:c, 7pjv:c, 7pjw:c, 7pjx:c, 7pjy:c, 7pjz:c, 8pkl:C, 8pva:C, 7q4k:AC, 8q4f:C, 6q97:h, 6q98:h, 6q9a:h, 7qg8:2, 7qgh:2, 7qgn:2, 7qgr:2, 8qk7:h, 8qoa:C, 8r3v:C1, 8r3v:C2, 8r6c:C, 8r8m:C, 8rcl:C1, 8rcl:C2, 8rcm:C1, 8rcm:C2, 8rcs:C1, 8rcs:C2, 8rct:C1, 8rct:C2, 7s1g:E, 7s1h:E, 7s1i:E, 7s1j:E, 7s1k:E, 7sa4:h, 7ss9:H, 7ssd:H, 7ssl:H, 7ssn:H, 7sso:H, 7ssw:H, 7st2:H, 7st6:H, 7st7:H, 8syl:c, 6szs:c, 8t5d:b, 8t5h:b, 6tbv:S031, 6tc3:S031, 7tos:S03, 4u1u:AC, 4u1u:CC, 4u1v:AC, 4u1v:CC, 4u20:AC, 4u20:CC, 4u24:AC, 4u24:CC, 4u25:AC, 4u25:CC, 4u26:AC, 4u26:CC, 4u27:AC, 4u27:CC, 5u4i:c, 5u9f:C, 5u9g:C, 7ug7:SC, 7uph:X, 8upo:I, 8upr:I, 8uql:I, 8uqm:I, 8uqp:I, 8ur0:I, 8urh:I, 8uri:I, 8urx:I, 8ury:I, 5uyk:C, 5uyl:C, 5uym:C, 5uyn:C, 5uyp:C, 5uyq:C, 5uz4:C, 4v4h:AC, 4v4h:CC, 4v4q:AC, 4v4q:CC, 4v4v:AC, 4v4w:AC, 4v50:AC, 4v50:CC, 4v52:AC, 4v52:CC, 4v53:AC, 4v53:CC, 4v54:AC, 4v54:CC, 4v55:AC, 4v55:CC, 4v56:AC, 4v56:CC, 4v57:AC, 4v57:CC, 4v5b:BC, 4v5b:DC, 4v5h:AC, 4v5y:AC, 4v5y:CC, 4v64:AC, 4v64:CC, 4v65:AO, 4v66:AO, 4v69:AC, 4v6c:AC, 4v6c:CC, 4v6d:AC, 4v6d:CC, 4v6e:AC, 4v6e:CC, 4v6k:BG, 4v6l:AG, 4v6m:AC, 4v6n:BF, 4v6o:AF, 4v6p:AF, 4v6q:AF, 4v6r:AF, 4v6s:BE, 4v6t:AC, 4v6v:AC, 4v6y:AC, 4v6z:AC, 4v70:AC, 4v71:AC, 4v72:AC, 4v73:AC, 4v74:AC, 4v75:AC, 4v76:AC, 4v77:AC, 4v78:AC, 4v79:AC, 4v7a:AC, 4v7b:AC, 4v7c:AC, 4v7d:BC, 4v7i:BC, 4v7s:AC, 4v7s:CC, 4v7t:AC, 4v7t:CC, 4v7u:AC, 4v7u:CC, 4v7v:AC, 4v7v:CC, 4v85:AC, 4v89:AC, 4v9c:AC, 4v9c:CC, 4v9d:AC, 4v9d:BC, 4v9o:BC, 4v9o:DC, 4v9o:HC, 4v9o:FC, 4v9p:BC, 4v9p:DC, 4v9p:HC, 4v9p:FC, 8vs9:S03, 8vsa:S03, 6vu3:I, 6vwl:b, 6vwm:b, 6vwn:b, 6vyq:I, 6vyr:I, 6vys:I, 6vyt:I, 6vyu:I, 6vyw:I, 6vyx:I, 6vyy:I, 6vyz:I, 6vz2:I, 6vz3:I, 6vz5:I, 6vz7:I, 6vzj:I, 6w6k:C, 6w77:C, 6w7m:C, 6w7n:C, 5wdt:c, 6wd0:H, 6wd1:H, 6wd2:H, 6wd3:H, 6wd4:H, 6wd5:H, 6wd6:H, 6wd7:H, 6wd8:H, 6wd9:H, 6wda:H, 6wdb:H, 6wdc:H, 6wdd:H, 6wde:H, 6wdf:H, 6wdg:H, 6wdh:H, 6wdi:H, 6wdj:H, 6wdk:H, 6wdl:H, 6wdm:H, 5we4:c, 5we6:c, 4wf1:AC, 4wf1:CC, 5wf0:c, 5wfk:c, 5wfs:c, 6wnv:H, 6wnw:H, 4woi:AC, 4woi:DC, 4www:QC, 4www:XC, 6x6t:I, 6x7f:I, 6x7k:I, 6x9q:I, 6xdq:I, 6xdr:I, 6xe0:B, 6xgf:I, 6xii:I, 6xij:I, 6xza:C1, 6xzb:C1, 6y69:c, 7y7c:C, 7y7d:C, 7y7e:C, 7y7f:C, 7y7g:C, 7y7h:C, 4ybb:AC, 4ybb:BC, 2ykr:C, 6ysr:c, 6yss:c, 6yst:c, 6ysu:c, 6ztj:AC, 6ztl:AC, 6ztm:AC, 6ztn:AC, 6zto:AC, 6ztp:AC, 7zta:S031, 6zu1:AC
15 7unr:c 208 48 0.2368 0.0865 0.3750 0.026 8cd1:c, 6spc:c, 6spe:c, 6spf:c, 6spg:c, 7unu:c, 7unv:c, 7unw:c
16 1ec6:A 87 69 0.2895 0.2529 0.3188 0.027 1ec6:B
17 1g0d:A 666 57 0.2105 0.0240 0.2807 0.10
18 5wwx:A 84 70 0.2368 0.2143 0.2571 0.24
19 8rdv:CT 205 37 0.1974 0.0732 0.4054 0.45 8rd8:CT, 8rdw:CT
20 5elt:B 152 25 0.1316 0.0658 0.4000 0.60 5elr:C, 5els:A, 5els:C, 5elt:A, 5emo:B, 5emo:A
21 1af7:A 274 52 0.2500 0.0693 0.3654 0.63 1bc5:A
22 4eso:B 251 36 0.1579 0.0478 0.3333 1.9 4eso:A, 4eso:C, 4eso:D
23 1b5o:A 382 47 0.1842 0.0366 0.2979 2.7 1b5o:B, 1b5p:A, 1b5p:B, 1bjw:A, 1bjw:B, 5bj3:A, 5bj3:B, 5bj3:C, 5bj3:D, 5bj4:A, 5bj4:B, 1bkg:A, 1bkg:B, 1bkg:C, 1bkg:D, 1gc3:A, 1gc3:B, 1gc3:C, 1gc3:D, 1gc3:E, 1gc3:F, 1gc3:G, 1gc3:H, 1gc4:A, 1gc4:B, 1gc4:C, 1gc4:D, 1gck:A, 1gck:B
24 1o4s:B 384 30 0.1316 0.0260 0.3333 2.9 1o4s:A
25 3p4g:B 313 42 0.1711 0.0415 0.3095 3.2 3p4g:A, 3p4g:C, 3p4g:D
26 3f3q:A 109 26 0.1184 0.0826 0.3462 4.5 3f3r:A, 3f3r:B
27 3lkk:B 238 30 0.1579 0.0504 0.4000 4.6 3lkk:A, 3ll5:A, 3ll5:B, 3ll5:C, 3ll5:D
28 2iq7:E 339 48 0.1842 0.0413 0.2917 5.5
29 6z0p:A 242 23 0.1316 0.0413 0.4348 5.7 6z0p:B
30 5zeb:c 210 47 0.1842 0.0667 0.2979 8.2 6dzi:k, 6dzk:C, 8fr8:G, 7kgb:c, 7msc:c, 7msh:c, 7msm:c, 7msz:c, 7mt2:c, 7mt3:c, 7mt7:c, 5o5j:C, 5o61:BC, 7sfr:c, 5v93:c, 8v9j:c, 8v9k:c, 8v9l:c, 8whx:d, 8wi7:d, 8wi9:d, 8wib:d, 8wid:d, 8wif:d, 5xyu:C, 5zep:c, 5zeu:c
31 5t45:A 708 31 0.1447 0.0155 0.3548 8.4 5m05:A
32 4jvh:A 176 25 0.1184 0.0511 0.3600 9.5
33 1t10:A 556 62 0.2105 0.0288 0.2581 9.6
34 7mf3:B 896 31 0.1447 0.0123 0.3548 9.7 1br1:A, 1br1:C, 1br1:E, 1br1:G, 1br4:A, 1br4:C, 1br4:E, 1br4:G, 7mf3:A, 6z47:A, 6z47:B
35 7nhk:d 206 54 0.2368 0.0874 0.3333 9.9 6o8w:c, 6o8x:c, 6o8y:c, 6o8z:c, 6o90:c, 7p7q:d, 7p7r:d, 7p7s:d, 7p7t:d, 7p7u:d, 6w6p:c, 6wua:c
36 7xss:B 1282 41 0.1974 0.0117 0.3659 10.0 8d9f:B, 8d9h:B, 7x8a:A, 7xso:A, 7xsp:B, 7xt4:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218