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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMLLERPQQKKNSRFYQMSPEERLASLLNEGQISADTKKEFENTALSSQIANHMIENQISETEVPMGVGLHLTVDETDYL
VPMATEEPSVIAALSNGAKIAQGFKTVNQQRLMRGQIVFYDVADPESLIDKLQVREAEIFQQAELSYPSIVKRGGGLRDL
QYRAFDESFVSVDFLVDVKDAMGANIVNAMLEGVAELFREWFAEQKILFSILSNYATESVVTMKTAIPVSRLSKGSNGRE
IAEKIVLASRYASLDPYRAVTHNKGIMNGIEAVVLATGNDTRAVSASCHAFAVKEGRYQGLTSWTLDGEQLIGEISVPLA
LATVGGATKVLPKSQAAADLLAVTDAKELSRVVAAVGLAQNLAALRALVSEGIQKGHMALQARSLAMTVGATGKEVEAVA
QQLKRQKTMNQDRALAILNDLR

The query sequence (length=422) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7m1z:B 425 422 0.9976 0.9906 0.9976 0.0 7m1z:A, 7m1z:C, 7m1z:D, 7m3h:A, 7m3h:B, 7m66:A, 7m66:C, 7m66:B, 7m66:D
2 5wpk:B 422 417 0.4408 0.4408 0.4460 9.09e-113 5wpj:A, 5wpk:A
3 6dio:C 428 420 0.4242 0.4182 0.4262 4.54e-98 6dio:A, 6dio:B, 6eev:A
4 1qax:A 425 418 0.4028 0.4000 0.4067 3.21e-91 8gdn:A, 8gdn:B, 4i4b:A, 4i4b:B, 4i56:A, 4i56:B, 4i6a:A, 4i6a:B, 4i6w:A, 4i6w:B, 4i6y:A, 4i6y:B, 1qax:B, 1qay:A, 1qay:B, 1r31:A, 1r31:B, 8sz6:A, 8sz6:B, 1t02:A, 8vlq:A, 8vlq:B
5 6p7k:A 375 376 0.3531 0.3973 0.3963 7.86e-75
6 3cd5:A 425 366 0.2156 0.2141 0.2486 2.98e-10 3bgl:A, 3bgl:B, 3bgl:C, 3bgl:D, 3cct:A, 3cct:B, 3cct:C, 3cct:D, 3ccw:A, 3ccw:B, 3ccw:C, 3ccw:D, 3ccz:A, 3ccz:B, 3ccz:C, 3ccz:D, 3cd0:A, 3cd0:B, 3cd0:C, 3cd0:D, 3cd5:B, 3cd5:C, 3cd5:D, 3cd7:A, 3cd7:B, 3cd7:C, 3cd7:D, 3cda:A, 3cda:B, 3cda:C, 3cda:D, 3cdb:A, 3cdb:B, 3cdb:C, 3cdb:D, 1dq8:A, 1dq8:B, 1dq8:C, 1dq8:D, 1dq9:A, 1dq9:B, 1dq9:C, 1dq9:D, 1dqa:A, 1dqa:B, 1dqa:C, 1dqa:D, 1hw8:A, 1hw8:B, 1hw8:C, 1hw8:D, 1hw9:A, 1hw9:B, 1hw9:C, 1hw9:D, 1hwi:A, 1hwi:B, 1hwi:C, 1hwi:D, 1hwj:A, 1hwj:B, 1hwj:C, 1hwj:D, 1hwk:A, 1hwk:B, 1hwk:C, 1hwk:D, 1hwl:A, 1hwl:B, 1hwl:C, 1hwl:D, 2q1l:A, 2q1l:B, 2q1l:C, 2q1l:D, 2q6b:A, 2q6b:B, 2q6b:C, 2q6b:D, 2q6c:A, 2q6c:B, 2q6c:C, 2q6c:D, 2r4f:A, 2r4f:B, 2r4f:C, 2r4f:D
7 6hr8:A 397 356 0.2038 0.2166 0.2416 3.70e-07 6hr8:B, 6hr8:C, 6hr8:D, 6hr8:E, 6hr8:F
8 8ecg:A 357 335 0.1896 0.2241 0.2388 2.38e-05
9 7pzb:A 227 101 0.0687 0.1278 0.2871 0.095 7pza:A, 7pza:B, 7pzb:B
10 5dai:A 247 95 0.0711 0.1215 0.3158 0.16
11 3anl:A 400 44 0.0450 0.0475 0.4318 0.36 3anl:B, 3anm:A, 3anm:B, 3ann:A, 3ann:B, 2egh:A, 2egh:B, 1jvs:A, 1jvs:B, 1ono:A, 1ono:B, 1onp:A, 1onp:B, 1q0h:A, 1q0l:A, 1q0q:A, 1q0q:B, 3r0i:A, 3r0i:B, 1t1r:A, 1t1r:B, 1t1s:A, 1t1s:B
12 7mfm:G 1483 70 0.0474 0.0135 0.2857 2.4 7mfm:H, 7mft:G
13 4f1m:A 278 60 0.0403 0.0612 0.2833 5.9 4f0f:A, 4f1o:A, 4f1t:A, 4yzm:A, 4yzm:B, 4yzn:A
14 7dvq:0 100 39 0.0332 0.1400 0.3590 7.3
15 3q08:A 241 18 0.0237 0.0415 0.5556 9.1 3q08:B, 3q08:C, 3q08:D, 3q08:E, 3q08:F, 3q08:G, 3q08:H, 3q08:I, 3q08:J, 3q08:K, 3q08:L, 3q08:M, 3q08:N, 3q08:O, 3q08:P, 3q08:Q, 3q08:R, 3q08:S, 3q08:T, 3q09:A, 3q09:B, 3q09:C, 3q09:D, 3q09:E, 3q09:F, 3q09:G, 3q09:H, 3q09:I, 3q09:J, 3q09:K, 3q09:L, 3q09:M, 3q09:N, 3q09:O, 3q09:P, 3q09:Q, 3q09:R, 3q09:S, 3q09:T, 2vxh:A, 2vxh:B, 2vxh:C, 2vxh:D, 2vxh:E, 2vxh:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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