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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMKLSLVISTSDAAFDALAFKGDLRKGMELAKRVGYQAVEIAVRDPSIVDWNEVKILSEELNLPICAIGTGQAYLADGLS
LTHPNDEIRKKAIERVVKHTEVAGMFGALVIIGLVRGRREGRSYEETEELFIESMKRLLELTEHAKFVIEPLNRYETDFI
NTIDDALRILRKINSNRVGILADTFHMNIEEVNIPESLKRAGEKLYHFHVADSNRWAPGCGHFDFRSVFNTLKEIGYNRY
VSVECLPLPGGMEEAAEIAFKTLKELIIKL

The query sequence (length=270) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5h1w:A 270 270 1.0000 1.0000 1.0000 0.0 5b7y:A, 5b7y:B, 5b80:A, 5b80:B, 5h1w:B, 5h6h:A, 5h6h:B
2 7cj5:A 292 244 0.2889 0.2671 0.3197 4.52e-26 7cj4:A, 7cj4:B, 7cj5:B, 7cj6:A, 7cj6:B, 7cj7:A, 7cj7:B, 7cj8:A, 7cj8:B, 7cj8:C, 7cj8:D, 7cj8:E, 7cj8:F, 7cj9:A, 7cj9:B, 7cj9:C, 7cj9:D, 7cj9:E, 7cj9:F, 7cj9:G, 7cj9:H
3 6wn6:B 264 250 0.2778 0.2841 0.3000 1.48e-21 6wn6:A, 6wn6:C, 6wn6:D
4 7x7w:A 288 122 0.1667 0.1562 0.3689 4.45e-21 7x7w:B
5 3vnl:A 291 249 0.2556 0.2371 0.2771 2.18e-19 7e9w:A, 7e9w:B, 7e9w:C, 7e9w:D, 3vni:A, 3vni:B, 3vni:C, 3vni:D, 3vnj:A, 3vnj:B, 3vnj:C, 3vnj:D, 3vnk:A, 3vnk:B, 3vnk:C, 3vnk:D, 3vnl:B, 3vnl:C, 3vnl:D, 3vnm:A, 3vnm:B, 3vnm:C, 3vnm:D
6 4pfh:A 298 211 0.2185 0.1980 0.2796 1.00e-18 5j8l:A, 5j8l:B, 5j8l:C, 5j8l:D, 2ou4:A, 2ou4:B, 2ou4:C, 2ou4:D, 4pfh:B, 4pgl:A, 4pgl:B, 4pgl:C, 4pgl:D, 4q7i:A, 4q7i:B, 2qul:A, 2qul:B, 2qul:C, 2qul:D, 2qum:A, 2qum:B, 2qum:C, 2qum:D, 2qun:A, 2qun:B, 2qun:C, 2qun:D, 4xsl:A, 4xsl:B, 4xsl:C, 4xsl:D, 4xsm:A, 4xsm:B, 4xsm:C, 4xsm:D, 4ytq:A, 4ytq:B, 4ytq:C, 4ytq:D, 4ytr:A, 4ytr:B, 4ytr:C, 4ytr:D, 4yts:A, 4yts:B, 4yts:C, 4yts:D, 4ytt:A, 4ytt:B, 4ytt:C, 4ytt:D, 4ytu:A, 4ytu:B, 4ytu:C, 4ytu:D
7 3vyl:A 297 238 0.2148 0.1953 0.2437 2.01e-18 3vyl:B, 3vyl:C, 3vyl:D, 3vyl:E, 3vyl:F, 3vyl:G, 3vyl:H
8 7ern:C 284 232 0.2259 0.2148 0.2629 8.07e-18 7erm:A, 7erm:B, 7erm:C, 7erm:D, 7ern:A, 7ern:B, 7ern:D, 7ero:A, 7ero:B, 7ero:C, 7ero:D
9 5zfs:B 294 228 0.2222 0.2041 0.2632 5.57e-17 5zfs:A
10 7dz4:C 286 217 0.2333 0.2203 0.2903 6.76e-17 7dz2:A, 7dz2:B, 7dz2:C, 7dz2:D, 7dz3:A, 7dz3:B, 7dz3:C, 7dz3:D, 7dz4:A, 7dz4:B, 7dz4:D, 7dz5:A, 7dz5:B, 7dz5:C, 7dz5:D, 7dz6:A, 7dz6:B, 7dz6:C, 7dz6:D
11 2hk1:A 289 106 0.1407 0.1315 0.3585 2.06e-16 2hk1:B, 2hk1:C, 2hk1:D
12 3kws:A 265 202 0.2370 0.2415 0.3168 2.86e-15 3kws:B
13 1i6n:A 278 123 0.1556 0.1511 0.3415 6.08e-11
14 3wqo:A 271 90 0.1074 0.1070 0.3222 5.11e-05 3wqo:B
15 3cqj:A 276 228 0.1926 0.1884 0.2281 6.83e-04 3cqj:B, 3cqk:A, 3cqk:B
16 2qw5:A 327 184 0.1481 0.1223 0.2174 0.008 2qw5:B
17 1de5:A 417 109 0.1037 0.0671 0.2569 0.13 1d8w:A, 1d8w:B, 1d8w:C, 1d8w:D, 1de5:B, 1de5:C, 1de5:D, 1de6:A, 1de6:B, 1de6:C, 1de6:D
18 5tnv:A 306 52 0.0593 0.0523 0.3077 0.53
19 8of1:A 505 104 0.1074 0.0574 0.2788 0.73 8of1:B, 8ofm:A, 8ofm:B
20 5hmq:D 624 99 0.0778 0.0337 0.2121 0.95 5hmq:A, 5hmq:B, 5hmq:C, 5hmq:E, 5hmq:F
21 3tva:A 282 98 0.0889 0.0851 0.2449 1.4 3tva:B
22 6ki3:B 300 80 0.0778 0.0700 0.2625 1.5 6khy:A, 6khy:C, 6khy:B, 6khy:D, 6ki3:A
23 6n2n:B 291 22 0.0370 0.0344 0.4545 2.0 6n2n:D, 6n2o:B, 6n2o:D
24 7suk:SP 2234 43 0.0630 0.0076 0.3953 2.5 6zqb:UT
25 3o0f:A 287 41 0.0556 0.0523 0.3659 3.0 3e0f:A
26 1gax:A 862 27 0.0444 0.0139 0.4444 3.1 1gax:B, 1ivs:A, 1ivs:B, 1wk9:A
27 3uva:C 405 31 0.0407 0.0272 0.3548 3.9 3uu0:A, 3uu0:B, 3uu0:C, 3uu0:D, 3uva:A, 3uva:B, 3uva:D, 3uxi:A
28 2zsj:A 350 58 0.0704 0.0543 0.3276 4.1 2zsj:B, 2zsj:C, 2zsj:D
29 1q9s:A 149 70 0.0704 0.1275 0.2714 5.7 1nb0:A, 1nb9:A, 1p4m:A
30 6dft:A 384 20 0.0333 0.0234 0.4500 7.3 6dft:C, 6dft:E, 6dft:G, 6dft:I, 6dft:K
31 8fpj:A 1345 59 0.0778 0.0156 0.3559 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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