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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMIKVLSPAKINLGLWVLGRLPSGYHEILTLYQEIPFYDEIYIREGVLRVETNIGIPQEENLVYKGLREFERITGIEINY
SIFIQKNIPPGAGLGGGSSNLAVVLKKVNELLGSPLSEEELRELVGSISADAPFFLLGKSAIGRGKGEVLEPVETEISGK
ITLVIPQVSSSTGRVYSSLREEHFVTPEYAEEKIQRIISGEVEEIENVLGDIARELYPEINEVYRFVEYLGFKPFVSGSG
STVYFFGGASEELKKAAKMRGWKVVELEL

The query sequence (length=269) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2v2q:B 270 269 1.0000 0.9963 1.0000 0.0 2v2q:A, 2v2v:A, 2v2v:B, 2v2z:A, 2v2z:B, 2v34:A, 2v34:B, 2v8p:A, 2v8p:B, 2vf3:A, 2vf3:B
2 4dxl:A 304 280 0.3048 0.2697 0.2929 1.38e-27 4ed4:A, 4emd:A
3 8ckh:A 281 260 0.3457 0.3310 0.3577 6.26e-25 8ckh:B
4 3pye:A 301 281 0.3123 0.2791 0.2989 2.55e-24 3pyf:A, 3pyg:A
5 1oj4:A 283 253 0.3234 0.3074 0.3439 6.58e-21 1oj4:B, 8qc7:A, 8qc7:B, 8qcc:A, 8qcc:B, 8qcn:A, 8qcn:B, 8qco:A, 8qco:B, 2ww4:A, 2ww4:B
6 4hac:A 312 136 0.1338 0.1154 0.2647 0.13 4hac:B, 6mde:A, 6mdf:A, 6mdf:B
7 4gvo:A 236 154 0.1487 0.1695 0.2597 0.41 4gvo:B
8 4ut4:A 345 59 0.0669 0.0522 0.3051 0.50 4ut4:B, 4utg:A, 4utg:B
9 2g88:A 331 81 0.1004 0.0816 0.3333 0.76 2odn:A, 2odw:A, 2oep:A, 1ube:A, 1ubf:A, 1ubg:A, 2zr9:A, 2zra:A, 2zrd:A, 2zre:A, 2zrf:A, 2zrg:A, 2zri:A, 2zrj:A, 2zrk:A, 2zrl:A, 2zrm:A, 2zro:A, 2zrp:A
10 5hgq:B 482 37 0.0483 0.0270 0.3514 1.2 5hgq:A, 5hgq:D, 5hgq:C
11 1mo4:A 324 70 0.0855 0.0710 0.3286 2.3 1g18:A, 1mo3:A, 1mo5:A, 1mo6:A
12 6k4t:A 260 63 0.0558 0.0577 0.2381 2.9 5axo:A, 5axr:A, 5aya:A, 5b15:A, 5b1u:A, 6k4x:A, 3vpe:A, 3vqz:A
13 7v9o:A 860 136 0.1301 0.0407 0.2574 5.2 7v9n:A, 7v9p:A, 7v9p:B, 7v9q:A
14 5c7h:A 281 97 0.1041 0.0996 0.2887 7.7 4pmj:A
15 8h0s:C 190 88 0.0892 0.1263 0.2727 8.4 8h0s:A, 8h0t:A, 4poo:A
16 8ahx:E 213 41 0.0558 0.0704 0.3659 8.7 8rb8:E, 8rb9:E, 8rbm:E, 8rbq:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218