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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGSS
KLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHEC
QQLLPSIPQLKEHLRKHW

The query sequence (length=178) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6cvq:A 180 178 0.9944 0.9833 0.9944 4.57e-132 6cvo:A, 6cvo:B, 6cvp:A, 6cvp:B, 6cvq:B, 6cvr:A, 6cvr:B, 6cvs:A, 6cvs:B, 6cvt:A, 6cvt:B, 4ndf:A, 4ndf:B, 4ndg:A, 4ndg:B, 4ndh:A, 4ndh:B, 4ndi:A, 4ndi:B
2 3sp4:B 204 199 0.2921 0.2549 0.2613 3.18e-14 3sp4:A, 3spd:A, 3spd:B, 3spd:C, 3spd:D, 3spl:A, 3spl:B, 3spl:C, 3spl:D, 3szq:A, 4xba:A, 4xba:B, 4ykl:B
3 5uvm:A 115 92 0.1573 0.2435 0.3043 1.22e-07 5uvm:B
4 6yqm:AAA 117 98 0.1629 0.2479 0.2959 1.32e-07 1av5:B, 6b42:A, 5ed3:B, 5ed6:B, 5emt:A, 5emt:B, 4eqe:B, 4eqg:B, 4eqh:B, 5i2e:A, 5i2e:B, 5i2f:A, 5ipc:A, 5ipd:A, 5ipe:A, 6j53:B, 6j58:B, 6j5s:B, 6j5z:A, 6j5z:D, 6j64:B, 6j65:B, 6j65:E, 5kly:A, 5kly:B, 5klz:B, 5km0:A, 5km0:D, 5km1:A, 5km2:A, 5km3:A, 5km4:A, 5km6:A, 5kma:A, 5kmb:A, 5kmb:B, 5kmc:A, 1kpe:B, 1kpf:A, 6n3v:A, 6n3w:A, 6n3x:A, 6n3y:A, 6n3y:B, 3o1c:A, 3o1x:A, 5o8i:B, 8p8p:A, 8pa6:A, 8pa6:B, 8pa9:A, 8paf:A, 8paf:B, 8pai:A, 8pwk:A, 3qgz:A, 3rhn:A, 4rhn:A, 5rhn:A, 1rzy:A, 3tw2:A, 5wa8:A, 5wa9:A, 4zkl:B, 4zkl:D
5 4egu:A 118 92 0.1461 0.2203 0.2826 2.53e-07 4egu:B
6 4ini:B 112 90 0.1404 0.2232 0.2778 8.83e-06 4ini:A, 5km5:B, 5km8:B, 5km9:B, 6yvp:AAA, 6yvp:BBB
7 6d6j:B 113 92 0.1292 0.2035 0.2500 1.80e-05 6d6j:A
8 4zgl:F 102 96 0.1517 0.2647 0.2812 2.94e-05 4zgl:B, 4zgl:C, 4zgl:H, 4zgl:I
9 3o0m:A 139 98 0.1517 0.1942 0.2755 4.96e-05 3o0m:B
10 3oxk:A 115 94 0.1404 0.2174 0.2660 6.24e-05 3oj7:A, 3omf:A
11 3n1s:J 119 103 0.1742 0.2605 0.3010 7.64e-04 3n1s:A, 3n1s:B, 3n1s:E, 3n1s:F, 3n1s:I, 3n1s:M, 3n1s:N, 3n1t:A, 3n1t:B, 3n1t:E, 3n1t:F
12 5osy:A 300 63 0.1067 0.0633 0.3016 0.007 3bl7:A, 3bl9:A, 3bla:A, 3bla:B, 5osy:B, 4qde:A, 4qde:D, 4qdv:A, 4qdv:C, 4qdv:D, 4qeb:A, 1st0:B, 1st0:A, 1st4:B, 1st4:A, 1xmm:B, 1xmm:A, 1xmm:C, 1xmm:D
13 2eo4:A 149 85 0.1404 0.1678 0.2941 0.009
14 8fit:A 229 49 0.1067 0.0830 0.3878 0.84 8fit:C
15 8eop:A 1687 36 0.0843 0.0089 0.4167 0.88
16 8ee6:A 1808 36 0.0843 0.0083 0.4167 0.94 8edw:A
17 1y23:B 141 95 0.1517 0.1915 0.2842 1.8 1y23:A, 1y23:C, 1y23:D, 1y23:E
18 1llc:A 320 38 0.0730 0.0406 0.3421 2.9 6j9t:B, 6j9t:D, 6j9t:E, 6j9t:C, 6j9t:F, 6j9u:A, 6j9u:C, 6j9u:D
19 3imi:A 143 119 0.1685 0.2098 0.2521 4.1 3imi:B, 3imi:C, 3imi:D
20 3r6f:A 130 25 0.0449 0.0615 0.3200 4.7
21 3l7x:A 157 29 0.0618 0.0701 0.3793 5.7
22 3ksv:A 141 102 0.1292 0.1631 0.2255 6.6
23 6bt4:A 165 40 0.0730 0.0788 0.3250 6.9
24 6jlz:I 430 59 0.0955 0.0395 0.2881 7.5
25 7qep:O4 100 16 0.0449 0.0800 0.5000 8.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218