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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMASTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHTKISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEK
FETYIGIDQSANSSRSDHAVVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGDEVV
FADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPFTPGNNGSNNKIKLLIDGKEVEFNKG
LGTVASNPSSIKYDVSGANVTRFISYVGIDRSANHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIP
KDTQTIELKSYSGKHTWADELVLGGALFMAN

The query sequence (length=351) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2ygm:B 352 351 1.0000 0.9972 1.0000 0.0 2ygl:A, 2ygl:B, 2ygm:A
2 2vng:B 173 164 0.2707 0.5491 0.5793 4.25e-63 2vng:A, 2vno:A, 2vno:B, 2vnr:A
3 2vng:B 173 161 0.2564 0.5202 0.5590 3.06e-58 2vng:A, 2vno:A, 2vno:B, 2vnr:A
4 7jrl:A 457 164 0.1453 0.1116 0.3110 5.12e-07 7jrm:A
5 2vmh:A 147 167 0.1425 0.3401 0.2994 1.03e-06 2vmg:A, 2vmi:A
6 2vmh:A 147 113 0.1054 0.2517 0.3274 0.022 2vmg:A, 2vmi:A
7 6z1s:A 381 67 0.0570 0.0525 0.2985 1.8
8 1r6m:A 236 106 0.0798 0.1186 0.2642 1.9
9 6v1s:E 276 27 0.0399 0.0507 0.5185 4.6 6v1s:A, 6v1s:B, 6v1s:C, 6v1s:D, 6v1s:F, 6v1s:G
10 2is4:B 632 56 0.0456 0.0253 0.2857 4.7
11 2is6:A 654 56 0.0456 0.0245 0.2857 4.8 2is1:A, 2is1:B, 2is2:A, 2is2:B, 2is4:A, 2is6:B
12 7vnn:D 641 27 0.0399 0.0218 0.5185 5.4 8ekm:A, 8ekm:B, 8ekm:C, 8ekm:D, 8ekm:E, 8ekm:F, 8ekm:G, 7vnj:A, 7vnj:B, 7vnj:C, 7vnj:D, 7vnj:E, 7vnj:F, 7vnj:G, 7vnn:A, 7vnn:B, 7vnn:C, 7vnn:E, 7vnn:F, 7vnn:G, 7yvq:A, 7yvq:B, 7yvq:C, 7yvq:D, 7yvq:E, 7yvq:F, 7yvq:G, 7yvs:A, 7yvs:B, 7yvs:C, 7yvs:D, 7yvs:E, 7yvs:F, 7yvs:G
13 6uwr:A 660 27 0.0399 0.0212 0.5185 5.4 6uwi:A, 6uwi:h, 6uwi:G, 6uwi:n, 6uwi:F, 6uwi:m, 6uwi:E, 6uwi:l, 6uwi:D, 6uwi:k, 6uwi:C, 6uwi:j, 6uwi:B, 6uwi:i, 6uwi:H, 6uwi:a, 6uwi:I, 6uwi:b, 6uwi:J, 6uwi:c, 6uwi:K, 6uwi:d, 6uwi:L, 6uwi:e, 6uwi:M, 6uwi:f, 6uwi:N, 6uwi:g, 6uwr:B, 6uwr:C, 6uwr:D, 6uwr:E, 6uwr:F, 6uwr:G, 6uwr:H, 6uwr:I, 6uwr:J, 6uwr:K, 6uwr:L, 6uwr:M, 6uwr:N, 6uwt:H, 6uwt:I, 6uwt:J, 6uwt:K, 6uwt:L, 6uwt:M, 6uwt:N, 6uwt:A, 6uwt:B, 6uwt:C, 6uwt:D, 6uwt:E, 6uwt:F, 6uwt:G
14 8ekk:A 533 27 0.0399 0.0263 0.5185 5.5 8ekk:B, 8ekk:C, 8ekk:D, 8ekk:E, 8ekk:F, 8ekk:G, 8ekl:A, 8ekl:B, 8ekl:C, 8ekl:D, 8ekl:E, 8ekl:F, 8ekl:G
15 8dcm:C 695 27 0.0399 0.0201 0.5185 5.6
16 3k7y:A 405 26 0.0370 0.0321 0.5000 5.8
17 2cz2:A 212 32 0.0399 0.0660 0.4375 6.2
18 8a0c:A 1116 44 0.0541 0.0170 0.4318 9.6 8a0c:B, 8a0m:A, 8a0m:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218