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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HMAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRPDLTGMVLEEGCP
EGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHGQSGMLLLGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTV
VCAVQAGEGETALE

The query sequence (length=174) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2iph:A 180 180 0.9138 0.8833 0.8833 1.54e-115 6bib:A, 6bib:B, 6bic:A, 6bic:B, 6bid:A, 5dg6:A, 5dgj:A, 5e0g:A, 5e0h:A, 5e0j:A, 4imq:A, 4imz:A, 4inh:B, 4inh:A, 4inh:C, 4inh:D, 4inh:E, 4inh:F, 4inh:G, 4inh:H, 2iph:B, 6t2i:A, 6t3g:A, 6t49:A, 6t4e:A, 6t4e:B, 6t5d:B, 6t5r:B, 5t6d:A, 5t6d:B, 5t6f:A, 5t6f:B, 5t6g:A, 5t6g:B, 6t6w:A, 6t71:B, 6t82:B, 6t8r:A, 6t8r:B, 6t8t:B, 6tal:B, 6taw:A, 6taw:B, 6tbo:A, 6tbo:B, 6tbp:A, 6tcf:B, 5tg1:A, 5tg2:A, 6tgl:B, 3ur9:A, 3ur9:B, 6w5h:A, 6w5h:B, 6w5h:C, 6w5h:D, 6w5j:A, 6w5j:B, 6w5k:A, 6w5k:B, 6w5k:C, 6w5k:D, 6w5l:A, 6w5l:B, 6w5l:C, 6w5l:D, 5wej:A, 5wej:B, 4xbb:A, 4xbc:A, 4xbd:A, 4xbd:B
2 6nir:B 170 169 0.6034 0.6176 0.6213 6.18e-78 8u1w:A
3 4x2v:A 174 172 0.5402 0.5402 0.5465 7.86e-64 4x2v:D
4 8xku:A 730 47 0.0977 0.0233 0.3617 1.2 8xkv:A
5 2vbc:A 600 55 0.1034 0.0300 0.3273 1.2 2jlr:A, 2jls:A, 2jlu:A, 2jlu:B, 2jlv:A, 2jlv:B, 2jlw:A, 2jlw:B, 2jlx:A, 2jlx:B, 2jly:A, 2jly:B, 2jlz:A, 2jlz:B, 2whx:A, 2wzq:A, 5xc6:A, 5xc6:B, 5yvj:B
6 2rau:A 350 81 0.1149 0.0571 0.2469 2.4
7 3i0o:A 329 49 0.0977 0.0517 0.3469 3.4 3i0q:A, 3q2m:A
8 3ty7:B 454 42 0.0690 0.0264 0.2857 3.8
9 4yet:B 200 51 0.0920 0.0800 0.3137 3.8 4yet:A
10 3qyy:B 156 94 0.1494 0.1667 0.2766 5.1 3qyy:A
11 8ulg:B 824 26 0.0575 0.0121 0.3846 5.4 7jsn:B, 6mzb:B, 8ufi:B, 8ugb:B, 8ugs:B
12 2o20:B 275 61 0.0977 0.0618 0.2787 6.1 2o20:A, 2o20:F, 2o20:G
13 3u4j:A 505 44 0.0805 0.0277 0.3182 6.6
14 4caz:A 489 44 0.0920 0.0327 0.3636 9.5 4caz:B, 2wme:A, 2wme:B, 2wme:C, 2wme:D, 2wme:E, 2wme:F, 2wme:G, 2wme:H, 2wox:A, 2wox:B, 2wox:C, 2wox:D, 2xdr:A, 2xdr:B, 2xdr:C, 2xdr:D, 3zqa:A, 3zqa:B, 3zqa:C, 3zqa:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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