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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLT
VIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDVCP
GTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECLGNCSEPDDPTKCVACRNFYLDGQCVETCPPPY
YHFQDWRCVNFSFCQDLHFKCRNSRCHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQ
ELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETLEIGNYSFYALDNQNL
RQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRTSFDKILLR
WEPYWPPDFRDLLGFMLFYKEAPYQNVTEFSWTVVDIDPPQRPSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKS
DIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAEDSELFELDYCLKGLKLPSRTFEDYLH
NVVFVPRPHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNV
VHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYV

The query sequence (length=798) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7sl6:A 819 817 0.9987 0.9731 0.9755 0.0 7mqs:F, 7mqs:E, 7sl1:A, 7sl1:B, 7sl2:A, 7sl2:B, 7sl6:B, 7sl7:A, 7sl7:B
2 8guy:F 835 836 0.9674 0.9246 0.9234 0.0 6ce7:P, 6ce9:M, 6ce9:P, 6ceb:M, 6ceb:P, 8guy:E, 6hn5:E, 5j3h:E, 7kd6:E, 7kd6:K, 7kd6:Q, 7kd6:W, 5kqv:E, 5kqv:F, 7mqo:F, 7mqo:E, 7mqr:E, 7mqr:F, 4oga:E, 7pg0:B, 7pg2:B, 7pg3:B, 7pg4:B, 7qid:C, 7sl3:A, 7sl3:B, 6sof:A, 6sof:C, 7u6e:F, 7u6e:E, 6vep:E, 6vep:K, 6vep:Q, 6vep:W, 6veq:K, 6veq:E, 3w11:E, 3w12:E, 3w13:E, 4xss:E, 4xst:E, 7yq3:F, 7yq3:E, 7yq4:E, 7yq4:F, 7yq5:F
3 7sl4:A 786 811 0.9662 0.9809 0.9507 0.0 8dtm:B
4 7yq5:E 799 816 0.9486 0.9474 0.9277 0.0 7pg0:A, 7pg2:A, 7pg3:A, 7pg4:A, 7sl4:B, 7yq6:E, 7yq6:F
5 7md4:B 778 804 0.9348 0.9589 0.9279 0.0
6 7md4:A 724 798 0.8722 0.9613 0.8722 0.0
7 6jk8:B 801 813 0.5539 0.5518 0.5437 0.0
8 6jk8:A 823 834 0.5564 0.5395 0.5324 0.0 1igr:A, 7v3p:B
9 6hn5:F 323 357 0.3521 0.8700 0.7871 0.0
10 8cls:B 853 861 0.3521 0.3294 0.3264 3.95e-132
11 8cls:A 837 852 0.3484 0.3321 0.3263 2.95e-130
12 8u4j:B 600 474 0.1880 0.2500 0.3165 1.49e-35
13 8u4j:B 600 312 0.0764 0.1017 0.1955 2.13e-09
14 5xwd:A 611 539 0.1905 0.2488 0.2820 9.21e-27
15 5xwd:A 611 318 0.1015 0.1326 0.2547 1.58e-12
16 4bqc:A 197 82 0.0326 0.1320 0.3171 1.28e-05
17 7md5:M 30 18 0.0188 0.5000 0.8333 3.09e-04 7md5:N
18 6gvk:A 201 41 0.0188 0.0746 0.3659 1.3 6gvl:A
19 6gvk:A 201 33 0.0150 0.0597 0.3636 5.2 6gvl:A
20 8by6:B 152 53 0.0251 0.1316 0.3774 3.5 7abg:A1, 6d0y:A, 1h2t:Z, 1h2u:X, 1h2u:Y, 1n52:B, 5oo6:B, 5oo6:E, 5oo6:H, 5oo6:K, 5oo6:N, 5oo6:Q, 5oo6:T, 5oo6:W, 5oob:D, 5oob:J, 5oob:B, 5oob:G, 8pmp:B, 8pnt:B, 8srr:B, 8suy:B
21 6g88:C 597 94 0.0313 0.0419 0.2660 5.3 6g88:B
22 6btm:B 948 50 0.0188 0.0158 0.3000 5.4
23 7e0d:A 604 37 0.0188 0.0248 0.4054 5.7 7e0c:A, 2e1m:A, 2e1m:B, 2e1m:C, 8jpw:A
24 7d62:A 294 59 0.0201 0.0544 0.2712 6.4 7d62:B
25 8oh5:C 1172 110 0.0363 0.0247 0.2636 9.4 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218