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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HLPQHVAIIMDGNNRFAKKNQMQKGDGHREGKNVLDPIVEHCVKTGVRALTVFAFSSENWNRPQYEVDLLMKLLEETIHE
QIPRMKKFNIALRFIGDRSRLPSHLVALMEDAEQQTAHHDAMTLTIAVSYGGMWDIANAAKQVAQAVSRGEIDADQINVD
LFEKYVSLNDLPAVDLLIRTGGDFRISNFLLWQAAYAELYFTDTLWPEFTVEEFDHALNVFS

The query sequence (length=222) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6szg:A 222 222 1.0000 1.0000 1.0000 3.84e-169 6szg:B, 6szh:B
2 1x07:A 231 222 0.4685 0.4502 0.4685 7.91e-72 5cqj:A, 2e98:A, 2e98:B, 2e99:A, 2e99:B, 2e9a:A, 2e9a:B, 2e9c:A, 2e9c:B, 2e9d:A, 2e9d:B, 4h2j:A, 4h2j:B, 4h2m:A, 4h2m:B, 4h2o:B, 4h2o:A, 4h38:A, 4h3a:A, 4h3a:B, 4h3c:A, 4h3c:B, 1jp3:A, 3sgt:B, 3sgv:B, 3sgv:A, 3sgx:A, 3sh0:B, 3sh0:A, 3th8:B, 1ueh:A, 1ueh:B, 1v7u:A, 3wyj:A, 1x06:A, 1x08:A, 1x09:A
3 7jlr:A 237 221 0.4324 0.4051 0.4344 7.69e-63 7jlj:A, 7jlm:A, 7jlm:B
4 8kgb:C 245 220 0.3964 0.3592 0.4000 4.16e-56 8kgb:A, 8kgb:B, 8kgb:D, 8x35:A, 8x35:B, 8x36:A, 8x36:B, 8x37:A, 8x37:B
5 4q9o:A 240 213 0.3874 0.3583 0.4038 7.24e-55 5kh4:A, 5kh4:B, 5kh5:B, 4q9m:A, 4q9m:B, 4q9o:B
6 5zhe:B 200 219 0.4099 0.4550 0.4155 8.62e-55
7 5hxq:C 227 217 0.3874 0.3789 0.3963 1.48e-52 5hxp:A, 5hxp:C, 5hxq:A, 5hxt:A, 5hxt:B
8 4u82:A 236 221 0.3423 0.3220 0.3439 2.51e-51 4h8e:A, 3wyi:A
9 6ime:A 285 209 0.3468 0.2702 0.3684 6.52e-51 6ime:B, 4onc:A, 4onc:B, 2vg2:A, 2vg2:C, 2vg2:B, 2vg2:D, 2vg3:A, 2vg3:C, 2vg3:B, 2vg3:D
10 7pay:A 329 212 0.3604 0.2432 0.3774 7.09e-49 7pax:A, 7pb0:A, 7pb1:A, 6w2l:A, 6z1n:A
11 3ugs:B 208 219 0.3514 0.3750 0.3562 2.06e-46 3ugs:A
12 5hc8:A 236 211 0.3559 0.3347 0.3744 4.74e-46 5hc7:A
13 2vg1:A 228 227 0.2973 0.2895 0.2907 2.73e-30 2vg0:A, 2vg0:B, 2vg1:B
14 7vqb:A 207 225 0.2793 0.2995 0.2756 1.41e-24 7vq9:A, 7vq9:B, 7vqa:A, 7vqa:B, 7vqb:B, 7vqc:B, 7vqd:A, 7vqd:B
15 7cav:B 222 229 0.2748 0.2748 0.2664 8.15e-24 7caq:A, 7caq:B, 7car:A, 7car:B, 7cas:B, 7cav:A, 7cav:C, 7cav:D, 7cav:E, 7cav:F, 7cav:G, 7cav:H, 7cc3:A, 7cc3:B, 7cc3:C, 7cc3:D, 7cc3:E, 7cc3:F, 7cc3:G, 7cc3:H
16 5ygk:C 217 215 0.2523 0.2581 0.2605 2.52e-12 5gul:A, 5gul:B, 5gul:C, 5gul:D, 5ygk:A, 5ygk:B, 5ygk:H, 5ygk:D, 5ygk:E, 5ygk:F, 5ygk:G
17 5xk6:A 218 221 0.2477 0.2523 0.2489 2.58e-06 5xk6:B, 5xk6:C, 5xk6:D, 5xk7:A, 5xk7:B, 5xk7:C, 5xk7:D, 5xk8:A, 5xk8:B, 5xk8:C, 5xk8:D, 5xk9:A, 5xk9:B, 5xk9:C, 5xk9:D, 5xk9:E, 5xk9:F, 5xk9:G, 5xk9:H
18 6w2l:B 195 106 0.1036 0.1179 0.2170 0.091 7pb1:B
19 1s99:A 186 103 0.1306 0.1559 0.2816 1.6 1sbr:A, 1sbr:B
20 9int:A 282 32 0.0586 0.0461 0.4062 3.5
21 6whg:A 523 22 0.0450 0.0191 0.4545 6.4 6whg:B, 6whg:C, 6whg:D
22 2ccw:A 129 46 0.0586 0.1008 0.2826 7.1 1dyz:A, 1dz0:A
23 5u8o:B 360 96 0.1351 0.0833 0.3125 9.2 5i0p:C, 5i0p:D, 5u8o:A, 5u8o:C, 5u8o:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218