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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HLEIPTAIKPRDGRFGSGPSKVRLEQLQTLTTTAAALFGTSHRQAPVKNLVGRVRSGLAELFSLPDGYEVILGNGGATAF
WDAAAFGLIDKRSLHLTYGEFSAKFASAVSKNPFVGEPIIITSDPGSAPEPQTDPSVDVIAWAHNETSTGVAVAVRRPEG
SDALVVIDATSGAGGLPVDIAETDAYYFAPQKNFASDGGLWLAIMSPAALSRIEAIAATGRWVPDFLSLPIAVENSLKNQ
TYNTPAIATLALLAEQIDWLVGNGGLDWAVKRTADSSQRLYSWAQERPYTTPFVTDPGLRSQVVGTIDFVDDVDAGTVAK
ILRANGIVDTEPYRKLGRNQLRVAMFPAVEPDDVSALTECVDWVVERL

The query sequence (length=368) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2fyf:A 368 368 1.0000 1.0000 1.0000 0.0 2fyf:B, 3vom:A, 3vom:B
2 3ffr:A 361 357 0.2500 0.2548 0.2577 4.07e-24
3 5yb0:B 349 361 0.2147 0.2264 0.2188 8.00e-19 5yb0:A, 5yb0:C, 5yb0:D, 5yb0:E, 5yb0:F, 5yb0:G, 5yb0:H, 5yb0:I, 5yb0:J, 5yb0:K, 5yd2:A, 5yd2:B
4 8a5v:E 366 377 0.2527 0.2541 0.2467 5.53e-18 8a5v:C, 8a5v:F, 8a5v:B, 8a5v:A, 8a5v:G, 8a5v:H, 8a5w:D, 8a5w:C, 8a5w:E, 8a5w:F, 8a5w:B, 8a5w:A, 8a5w:H, 3e77:A, 3e77:B
5 3qbo:B 359 283 0.1957 0.2006 0.2544 3.50e-11 3qbo:A
6 4azj:A 360 365 0.2147 0.2194 0.2164 1.15e-10 4azj:B, 4azk:A, 4azk:B, 2bhx:A, 2bhx:B, 2bi1:A, 2bi1:B, 2bi2:A, 2bi2:B, 2bi3:A, 2bi3:B, 2bi5:A, 2bi5:B, 2bi9:A, 2bi9:B, 2bia:A, 2bia:B, 2bie:A, 2bie:B, 2big:A, 2big:B, 1w23:A, 1w23:B
7 1bt4:A 361 368 0.2174 0.2216 0.2174 8.09e-10 2c0r:A, 2c0r:B, 1w3u:A
8 2dr1:A 381 382 0.2120 0.2047 0.2042 9.81e-10 2dr1:B
9 6czy:A 362 261 0.1766 0.1796 0.2490 1.58e-09 6czy:B, 6czy:C, 6czy:D, 6czz:A, 6czz:B, 6czz:C, 6czz:D
10 1bjo:A 360 368 0.2255 0.2306 0.2255 9.97e-08 1bjo:B
11 7t7j:B 360 284 0.1766 0.1806 0.2289 1.37e-06 7t7j:A
12 1m32:B 362 169 0.1168 0.1188 0.2544 0.005 1m32:A, 1m32:C, 1m32:D, 1m32:E, 1m32:F
13 3zrq:A 382 231 0.1603 0.1545 0.2554 0.005 3zrp:A, 3zrp:B, 3zrq:B, 3zrr:A, 3zrr:B
14 2yri:A 352 292 0.1957 0.2045 0.2466 0.006 2yri:B, 2yrr:A, 2yrr:B
15 6xdk:D 359 287 0.1766 0.1811 0.2265 0.007 6xdk:B, 6xdk:A, 6xdk:C
16 1iug:A 348 210 0.1413 0.1494 0.2476 0.015 1iug:B
17 3qm2:B 331 162 0.1168 0.1299 0.2654 0.019 3qm2:A
18 8odq:D 410 71 0.0652 0.0585 0.3380 0.38 8odq:B
19 7cep:A 414 171 0.1250 0.1111 0.2690 0.50 7ceo:A, 7cer:A, 7ces:A, 7e6b:A, 7e6c:A, 7e6e:A, 7e6f:A, 5j8q:A, 6kfz:A, 7xej:A, 7xek:A, 7xen:A, 7xep:A, 7xet:A, 5xt5:A, 5xt5:B, 5xt6:A, 5xt6:B, 5zsk:A, 5zso:A
20 3isl:A 387 71 0.0625 0.0594 0.3239 1.6 3isl:B
21 7d4i:3B 242 74 0.0571 0.0868 0.2838 1.8 7aju:CB, 7d4i:3C, 7d5s:3C, 7d5t:3B, 7d5t:3C, 7d63:3C, 6ke6:3C, 6lqp:3C, 6lqq:3C, 6lqr:3C, 6lqs:3C, 6lqt:3C, 6lqu:3C, 6lqv:3C, 7suk:SD, 5wlc:SD, 6zqd:CA, 6zqd:CB
22 3gzc:A 403 187 0.1413 0.1290 0.2781 2.1 3gzc:B, 3gzd:A, 3gzd:B, 3gzd:C, 3gzd:D
23 2wym:A 303 68 0.0543 0.0660 0.2941 3.0 2wym:B, 2wym:C, 2wym:D, 2wym:E, 2wym:F
24 1fcv:A 324 65 0.0516 0.0586 0.2923 3.4
25 3afg:B 507 83 0.0598 0.0434 0.2651 4.2 3afg:A
26 8wm6:e 169 72 0.0435 0.0947 0.2222 4.7 8wmv:e, 8wmw:e
27 5cof:A 172 56 0.0625 0.1337 0.4107 5.7
28 1n31:A 386 53 0.0462 0.0440 0.3208 5.7 1elq:A, 1elq:B, 1elu:A, 1elu:B, 1n2t:A, 1n2t:B, 1n31:B
29 7x6v:A 1381 109 0.0842 0.0224 0.2844 6.2
30 7x6s:A 1453 109 0.0842 0.0213 0.2844 6.2 5ltf:A, 5ltn:A, 5ltn:B, 5t2t:A
31 6pd2:C 616 79 0.0489 0.0292 0.2278 6.7 6pd1:A, 6pd1:B, 6pd1:D, 6pd2:A, 6pd2:B, 6pd2:D
32 6pk3:B 400 85 0.0707 0.0650 0.3059 8.3 6pk1:A, 6pk1:B, 6pk3:A
33 4ifd:H 295 57 0.0489 0.0610 0.3158 8.5 5c0x:H, 6fsz:HH, 5jea:H, 5k36:H, 8qcf:I
34 7vwt:A 326 39 0.0408 0.0460 0.3846 9.2 7vwt:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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