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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HKNMYDHTEITTDSLLALLGSEKVKIIDVRSADAYNGWRMRGEVRGGHIKGAKSLPAKWLTDPEWLNIVRFKQIRPEDAI
VLYGYTPEECEQTATRFKENGYNNVSVFHRFHPDWTGNDAFPMDRLEQYNRLVPAEWVNGLISGEEIPEYDNDTFIVCHA
HYRNRDAYLSGHIPGATDMDTLALESPETWNRRTPEELKKALEEHGITASTTVVLYGKFMHPDNADEFPGSAAGHIGAIR
LAFIMMYAGVEDVRVLNGGYQSWTDAGFAISKDDVPKTTVPEFGAPIPSRPEFAVDIDEAKEMLQSEDSDLVCVRSYPEY
IGEVSGYNYIKKKGRIPGAIFAECGSDAYHMENYRNHDHTTREYHEIEDIWAKSGIIPKKHLAFYSGTGWRGSEAWFNAL
LMGWPRVSVYDGGWFEWSNDPENPYETGVP

The query sequence (length=430) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ktv:A 431 430 0.9977 0.9954 0.9977 0.0 6h98:A, 6h99:A, 6h9a:A, 6ktw:A, 6ktx:A, 6ktz:A, 6ku1:A, 6ku1:B, 6ku2:A, 6ku2:E, 6kvw:A, 6kvw:B, 6kvy:A, 6kvz:A, 6kw0:A, 6kw0:B
2 1h4k:X 271 262 0.1651 0.2620 0.2710 7.72e-10
3 1h4k:X 271 130 0.0767 0.1218 0.2538 0.049
4 1orb:A 293 273 0.1535 0.2253 0.2418 3.22e-09
5 4jgt:A 280 256 0.1442 0.2214 0.2422 6.05e-08 4jgt:B, 4jgt:C
6 5wqk:A 293 212 0.1256 0.1843 0.2547 1.22e-07 5wqj:A, 5wqj:B, 5wqk:B
7 5wqk:A 293 104 0.0628 0.0922 0.2596 0.40 5wqj:A, 5wqj:B, 5wqk:B
8 2eg3:A 230 267 0.1651 0.3087 0.2659 0.001 2eg3:B, 2eg4:A, 2eg4:B
9 6qtz:o 325 109 0.0651 0.0862 0.2569 1.1 6qik:o, 6ri5:o, 6rzz:o, 6s05:o
10 6n8n:W 377 109 0.0651 0.0743 0.2569 1.5 6n8o:W
11 6mxv:B 251 44 0.0349 0.0598 0.3409 1.6
12 1cb7:B 483 57 0.0442 0.0393 0.3333 2.3 1cb7:D, 1ccw:B, 1ccw:D, 6h9e:B, 6h9e:D, 6h9f:B, 6h9f:D, 1i9c:B, 1i9c:D
13 4h7u:A 577 66 0.0465 0.0347 0.3030 2.5
14 5ey5:B 383 40 0.0326 0.0366 0.3500 5.5 5ey5:D
15 1qxn:A 137 65 0.0395 0.1241 0.2615 6.6 1qxn:B
16 5kzm:B 395 41 0.0372 0.0405 0.3902 7.7
17 4xfe:A 306 82 0.0535 0.0752 0.2805 7.9
18 3tp9:A 473 29 0.0279 0.0254 0.4138 7.9 3tp9:B
19 4gme:A 403 39 0.0349 0.0372 0.3846 7.9 4gme:C, 3vcn:A, 3vcn:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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