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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HKLFPKFSQGLAQDPTTRRIWYGLAMAHDFESHDGMTEENLYQKIFASHFGQLSIIFLWTSGNLFHVAWQGNFEQWVTDP
VHIRPIAHAIWDPHFGQPAVEAFTRGGASGPVNISTSGVYQWWYTIGMRTNQDLYVGSVFLALVSAIFLFAGWLHLQPNF
QPSLSWFKDAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGQHVGWDNFLSVLPHPQGLTPFFTGNWAAYAQSPDTAS
HVFGTAQGSGQAILTFLGGFHPQTQSLWLTDMAHHHLAIAVIFIVAGHMYRTNFGIGHRMQAILEAHTPPSGSLGAGHKG
LFDTVNNSLHFQLGLALASVGTITSLVAQHMYSLPPYAFQAIDFTTQAALYTHHQYIAGFIMCGAFAHGAIFFIRDYDPE
QNKGNVLARMLDHKEALISHLSWVSLFLGFHTLGLYVHNDVMQAFGTPEKQILIEPVFAQWIQAAHGKALYGFDFLLSSK
TSAAFANGQSLWLPGWLDAINNNQNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDG
PGRGGTCDISAYDAFYLAVFWMLNTIGWVTFYWHWKHLTLWQGNVAQFDESSTYLMGWLRDYLWLNSSQLINGYNPFGMN
SLSVWAWTFLFGHLIYATGFMFLISWRGYWQELIETLVWAHEKTPLANLVYWKDKPVALSIVQARLVGLAHFSVGYIFTY
AAFLIASTSGRF

The query sequence (length=732) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7d0j:B 734 731 0.9986 0.9959 1.0000 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
2 6igz:B 733 729 0.8770 0.8759 0.8807 0.0
3 7yca:B 732 729 0.8525 0.8525 0.8560 0.0
4 7y5e:BN 732 729 0.8361 0.8361 0.8395 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
5 7wfd:AB 734 729 0.8484 0.8460 0.8519 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
6 6kif:B 733 729 0.8306 0.8295 0.8340 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
7 6vpv:B 737 734 0.8320 0.8263 0.8297 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
8 8wm6:B 732 729 0.8142 0.8142 0.8176 0.0 8wmj:B, 8wmv:B, 8wmw:B
9 6kmw:aB 740 737 0.8347 0.8257 0.8290 0.0 6kmw:cB, 6kmw:bB
10 7blz:B 731 729 0.8142 0.8153 0.8176 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
11 7fix:B1 740 736 0.8265 0.8176 0.8220 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
12 7qco:B 734 733 0.8019 0.7997 0.8008 0.0 7qco:G, 7qco:g, 7qco:b
13 6ly5:b 732 729 0.7937 0.7937 0.7970 0.0 6l4u:B
14 6lu1:B 713 732 0.8142 0.8359 0.8142 0.0
15 6k61:B 740 736 0.8046 0.7959 0.8003 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
16 7dr0:B 706 732 0.8074 0.8371 0.8074 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
17 6kmx:aB 727 732 0.7787 0.7840 0.7787 0.0 6kmx:bB, 6kmx:cB
18 7lx0:H 739 736 0.7705 0.7632 0.7663 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
19 7s3d:B 742 739 0.7691 0.7588 0.7618 0.0 7s3d:H, 7s3d:b
20 7f4v:aB 725 730 0.7268 0.7338 0.7288 0.0 7f4v:bB, 7f4v:cB
21 7dwq:B 659 726 0.6926 0.7693 0.6983 0.0 7coy:aB, 7coy:bB, 7coy:cB
22 5l8r:A 743 754 0.4713 0.4643 0.4576 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
23 7yca:A 742 752 0.4563 0.4501 0.4441 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
24 6k61:A 742 750 0.4454 0.4394 0.4347 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
25 7y5e:AN 745 753 0.4577 0.4497 0.4449 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
26 6tra:A 746 757 0.4577 0.4491 0.4425 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
27 7f4v:aA 772 776 0.4590 0.4352 0.4330 0.0 7f4v:bA, 7f4v:cA
28 5oy0:A 751 755 0.4549 0.4434 0.4411 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
29 8wm6:A 742 753 0.4481 0.4420 0.4356 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
30 6igz:A 740 752 0.4495 0.4446 0.4375 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
31 7dr0:A 739 751 0.4495 0.4452 0.4381 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
32 7blz:A 743 753 0.4536 0.4468 0.4409 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
33 7qco:A 728 753 0.4495 0.4519 0.4369 0.0 7qco:E, 7qco:e, 7qco:a
34 6kif:A 751 766 0.4495 0.4381 0.4295 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
35 7s3d:A 749 762 0.4440 0.4339 0.4265 0.0 7s3d:G, 7s3d:a
36 6ly5:a 742 756 0.4440 0.4380 0.4299 0.0 6l4u:A
37 7dwq:A 726 756 0.4331 0.4366 0.4193 0.0
38 6kmw:aA 721 756 0.4481 0.4549 0.4339 0.0 6kmw:bA, 6kmw:cA
39 7lx0:G 751 749 0.4495 0.4381 0.4393 0.0 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
40 7coy:aA 685 730 0.4153 0.4438 0.4164 0.0 7coy:bA, 7coy:cA
41 6kmx:aA 717 753 0.4317 0.4407 0.4197 2.23e-178 6kmx:bA, 6kmx:cA
42 8jze:b 663 736 0.4235 0.4676 0.4212 2.81e-176 8jzf:b
43 8jjr:b 659 746 0.4290 0.4765 0.4209 1.55e-174
44 8jw0:b 617 719 0.4071 0.4830 0.4145 1.94e-174
45 8jjr:a 665 740 0.3142 0.3459 0.3108 1.74e-102
46 7zq9:B2 180 218 0.2240 0.9111 0.7523 1.63e-97
47 7zq9:B2 180 52 0.0355 0.1444 0.5000 0.001
48 8jw0:a 645 735 0.3183 0.3612 0.3170 4.94e-94
49 8jze:a 670 742 0.3019 0.3299 0.2978 1.26e-93 8jzf:a
50 5v8k:A 600 236 0.0915 0.1117 0.2839 7.73e-11
51 6m32:A 628 80 0.0396 0.0462 0.3625 1.27e-05 6m32:a
52 8gwa:A 667 80 0.0396 0.0435 0.3625 1.45e-05 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
53 7vzg:a 858 123 0.0410 0.0350 0.2439 0.014 7vzg:A, 7vzr:A, 7vzr:a
54 6bxj:A 619 44 0.0219 0.0258 0.3636 5.4 3bn3:A, 3bqm:B, 3bqm:C, 3bqn:B, 3bqn:C, 6bxb:A, 6bxb:B, 6bxf:A, 6bxf:B, 6ckb:A, 6ckb:B, 1cqp:A, 1cqp:B, 3e2m:A, 3e2m:B, 3eob:I, 3eob:J, 3f74:C, 3f78:A, 3f78:B, 3f78:C, 3hi6:A, 3hi6:B, 2ica:A, 4ixd:A, 7kc3:C, 7kc5:A, 7kc5:C, 7kc6:C, 7kc6:A, 1lfa:A, 1lfa:B, 3m6f:A, 1mjn:A, 1mq8:B, 1mq8:D, 1mq9:A, 2o7n:A, 1rd4:A, 1rd4:B, 1rd4:C, 1rd4:D, 1t0p:A, 3tcx:B, 3tcx:D, 3tcx:F, 3tcx:H, 3tcx:J, 3tcx:L, 3tcx:N, 3tcx:P, 3tcx:R, 3tcx:T, 3tcx:V, 3tcx:X, 3tcx:Z, 3tcx:b, 1xdd:A, 1xdd:B, 1xdg:A, 1xdg:B, 1xuo:A, 1xuo:B, 1zoo:A, 1zoo:B, 1zop:A, 1zop:B
55 9fp6:A 732 21 0.0150 0.0150 0.5238 6.3 9fp6:B, 9fp6:C, 9fp6:D, 9fp6:E, 9fp6:F
56 5e6u:A 583 34 0.0191 0.0240 0.4118 6.5 5e6r:A, 5e6s:A, 5e6s:C, 5e6s:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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