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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HKIKGTVVLMPKNELEVNLNAFLGRSVSLQLISATKADAHGKGKVGKDTFLEGINTSLPTLGAGESAFNIHFEWDGSMGI
PGAFYIKNYMQVEFFLKSLTLEAISNQGTIRFVCNSWVYNTKLYKSVRIFFANHTYVPSETPAPLVEYREEELKSLRGNG
TGERKEYDRIYDYDVYNDLGNPDKSEKLARPVLGGSSTFPYPRRGRTGRGPTVTDPNTEKQGEVFYVPRDENLGHLKSKD
ALEIGTKSLSQIVQPAFESAFDLKSTPIEFHSFQDVHDLYEGGIKLPRDVISTIIPLPVIKELYRTDGQHILKFPQPHVV
QVSQSAWMTDEEFAREMIAGVNPCVIRGLEEFPPKSNLDPAIYGDQSSKITADSLDLDGYTMDEALGSRRLFMLDYHDIF
MPYVRQINQLNSAKTYATRTILFLREDGTLKPVAIELSLPHVSQVVLPAKEGVESTIWLLAKAYVIVNDSCYHQLMSHWL
NTHAAMEPFVIATHRHLSVLHPIYKLLTPHYRNNMNINALARQSAINANGIIETTFLPSKYSVEMSSAVYKNWVFTDQAL
PADLIKRGVAIKDPSTPHGVRLLIEDYPYAADGLEIWAAIKTWVQEYVPLYYARDDDVKNDSELQHWWKEAVEKGHGDLK
DKPWWPKLQTLEDLVEVCLIIIWIASALHAAVNFGQYPYGGLIMNRPTASRRLLPEKGTPEYEEMINNHEKAYLRTITSK
LPTLISLSVIEILSTHASDEVYLGQRDNPHWTSDSKALQAFQKFGNKLKEIEEKLVRRNNDPSLQGNRLGPVQLPYTLLY
PSSEEGLTFRGIPNSISI

The query sequence (length=818) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1yge:A 839 834 0.9976 0.9726 0.9784 0.0 3bnb:A, 3bnc:A, 3bnd:A, 3bne:A, 5eeo:A, 1f8n:A, 1fgm:A, 1fgo:A, 1fgq:A, 1fgr:A, 1fgt:A, 3pzw:A, 2sbl:B, 2sbl:A, 7soi:A, 7soi:B, 7soj:A, 7soj:B, 5t5v:A, 5t5v:B, 5tqn:A, 5tqn:B, 5tqo:A, 5tqo:B, 5tqp:A, 5tqp:B, 5tr0:A, 5tr0:B, 4wfo:A, 4wha:A, 1y4k:A
2 1no3:A 851 850 0.7298 0.7015 0.7024 0.0 1hu9:A, 1ik3:A, 1jnq:A, 1lnh:A, 1n8q:A, 1rov:A, 1rrh:A, 1rrl:A, 1rrl:B
3 2iuk:A 835 838 0.7029 0.6886 0.6862 0.0 2iuk:B
4 2iuj:A 833 837 0.6687 0.6567 0.6535 0.0
5 8i6y:A 844 848 0.5868 0.5687 0.5660 0.0 8i6y:B
6 5med:A 569 522 0.1870 0.2689 0.2931 2.18e-49 5med:B, 5mee:A, 5mee:B, 5mef:A, 5mef:B, 5meg:A, 5meg:B
7 3dy5:A 1002 510 0.1797 0.1467 0.2882 1.10e-46 3dy5:C, 1u5u:A, 1u5u:B
8 3fg3:A 687 513 0.1797 0.2140 0.2865 3.46e-46 3fg1:A, 3fg1:B, 3fg1:C, 3fg1:D, 3fg3:B, 3fg3:C, 3fg3:D, 3fg4:A, 3fg4:B, 3fg4:C, 3fg4:D, 2fnq:A, 2fnq:B, 4qwt:A, 4qwt:B, 4qwt:C, 4qwt:D
9 3vf1:A 680 515 0.1785 0.2147 0.2835 1.29e-43 3vf1:B
10 6ncf:B 676 496 0.1650 0.1997 0.2722 1.27e-40 6ncf:A, 6ncf:C, 6ncf:D, 3o8y:A, 3o8y:B, 7ttk:A, 7ttk:B, 7ttl:A, 7ttl:D, 3v92:B, 3v92:A, 3v98:A, 3v98:B
11 4g33:A 661 492 0.1736 0.2148 0.2886 4.12e-40 4g32:A, 5ir4:A, 5ir5:A, 5lc8:A, 4rpe:A
12 7ttl:C 617 501 0.1663 0.2204 0.2715 3.85e-39 6n2w:A, 6n2w:B
13 3rde:A 552 497 0.1601 0.2373 0.2636 1.10e-38 3rde:B, 3rde:C, 3rde:D
14 7ttj:A 643 495 0.1626 0.2068 0.2687 1.31e-38 7ttl:B, 3v99:A
15 3v99:B 639 495 0.1626 0.2081 0.2687 2.23e-38
16 4nre:A 675 528 0.1834 0.2222 0.2841 1.90e-37 7laf:A, 7laf:B
17 7ttj:B 590 495 0.1650 0.2288 0.2727 3.68e-37
18 8ghc:A 662 506 0.1638 0.2024 0.2648 2.35e-36 8ghb:A, 8ghc:B, 8ghd:A, 8ghd:B, 8ghd:C, 8ghd:D, 8ghd:E, 8ghd:F, 8ghe:B, 8ghe:C, 8ghe:D, 8ghe:A
19 2p0m:A 662 493 0.1540 0.1903 0.2556 1.11e-35 1lox:A, 2p0m:B
20 3d3l:A 451 488 0.1504 0.2727 0.2520 1.28e-32 3d3l:B
21 6ns4:A 685 405 0.1357 0.1620 0.2741 3.20e-27 6ns3:A, 6ns4:B, 6ns5:A, 6ns5:B, 6ns6:A, 6ns6:B
22 6ns2:A 634 405 0.1357 0.1751 0.2741 3.21e-27 6ns2:C
23 5fx8:A 563 375 0.1259 0.1829 0.2747 1.32e-13 5fx8:B
24 5fno:A 568 390 0.1222 0.1761 0.2564 3.35e-13 5fno:B
25 5ek8:A 668 232 0.0660 0.0808 0.2328 0.002
26 8sm9:F 344 102 0.0293 0.0698 0.2353 0.28 8sm9:B, 8sm9:D, 8sm9:H
27 4v7j:Ay 94 66 0.0208 0.1809 0.2576 2.5 4v7j:By, 4v7k:Ay, 4v7k:By
28 7xql:A 444 185 0.0550 0.1014 0.2432 3.2
29 3k70:C 1121 53 0.0208 0.0152 0.3208 3.3 3k70:F, 5ld2:C, 7mr3:C, 6sjb:C, 6sje:C, 6sjf:C, 6sjg:C, 6t2u:C, 6t2v:C, 1w36:C
30 8b1t:C 1080 53 0.0208 0.0157 0.3208 3.6 8b1u:C, 1w36:F
31 7mr4:C 1083 53 0.0208 0.0157 0.3208 3.8
32 2de6:B 390 128 0.0367 0.0769 0.2344 5.8 7bug:A, 7bug:B, 7bug:C, 7bui:A, 7bui:B, 7bui:C, 2de5:A, 2de5:B, 2de5:C, 2de6:A, 2de6:C, 2de7:A, 2de7:B, 2de7:C, 6ll0:A, 6ll0:B, 6ll0:C, 6ll1:A, 6ll1:B, 6ll1:C, 6ll4:A, 6ll4:B, 6ll4:C, 6llf:A, 6llf:B, 6llf:C, 6llh:A, 6llh:B, 6llh:C, 6llk:A, 6llm:A, 4nb8:A, 4nb8:B, 4nb8:C, 4nb9:A, 4nb9:B, 4nb9:C, 4nba:A, 4nba:B, 4nba:C, 4nbb:A, 4nbb:B, 4nbb:C, 4nbc:A, 4nbc:B, 4nbc:C, 4nbd:A, 4nbd:B, 4nbd:C, 4nbe:A, 4nbe:B, 4nbe:C, 4nbf:A, 4nbf:B, 4nbf:C, 4nbg:A, 4nbg:B, 4nbg:C, 4nbh:A, 4nbh:B, 4nbh:C, 3vmg:A, 3vmg:B, 3vmg:C, 3vmh:A, 3vmh:B, 3vmh:C, 3vmi:A, 3vmi:B, 3vmi:C, 1ww9:A
33 4xjn:A 395 65 0.0244 0.0506 0.3077 6.2 5wkn:A, 5wkn:B, 4xjn:B, 4xjn:C, 4xjn:D, 4xjn:E, 4xjn:F, 4xjn:G, 4xjn:H, 4xjn:I, 4xjn:J, 4xjn:K, 4xjn:L, 4xjn:M

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218