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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HIEGRHMAPKRVVQLSLKMPTHAVCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVKEPIGKARWPLDTDA
DMVVSVGTASKELKDFKVRVSYFGEQEDQALGRSVLYLTGVDISLEVDTGRTGKVKRSQGDKKTWRWGPEGYGAILLVNC
DRDNHRSAEPDLTHSWLMSLADLQDMSPMLLSCNGPDKLFDSHKLVLNVPFSDSKRVRVFCARGGNSLSDYKQVLGPQCL
SYEVERQPGEQEIKFYVEGLTFPDADFLGLVSLSVSLVDPGTLPEVTLFTDTVGFRMAPWIMTPNTQPPEELYVCRVMDT
HGSNEKFLEDMSYLTLKANCKLTICPQVENRNDRWIQDEMEFGYIEAPHKSFPVVFDSPRNRGLKDFPYKRILGPDFGYV
TREIPLPGPSSLDSFGNLDVSPPVTVGGTEYPLGRILIGSSFPKSGGRQMARAVRNFLKAQQVQAPVELYSDWLSVGHVD
EFLTFVPTSDQKGFRLLLASPSACLKLFQEKKEEGYGEAAQFDGLKHQAKRSINEMLADRHLQRDNLHAQKCIDWNRNVL
KRELGLAESDIVDIPQLFFLKNFYAEAFFPDMVNMVVLGKYLGIPKPYGPIINGRCCLEEKVQSLLEPLGLHCIFIDDYL
SYHELQGEIHCGTNVRRKPFPFKWWNMVP

The query sequence (length=669) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5hp5:A 669 669 1.0000 1.0000 1.0000 0.0 5hp5:B
2 5n0z:A 638 662 0.5590 0.5862 0.5650 0.0 3b1t:A, 3b1u:A, 2dew:X, 2dex:X, 2dey:X, 4dkt:A, 2dw5:A, 5n0m:A, 5n0y:A, 5n1b:A, 1wda:A
3 7d56:C 640 667 0.5695 0.5953 0.5712 0.0 7d56:B, 7d56:A, 7d5r:A, 7d5r:B, 7d8n:A, 7d8n:B, 7dan:C, 7dan:B, 7dan:A
4 4x8g:A 606 663 0.5351 0.5908 0.5400 0.0 1wd9:A
5 4n2i:A 662 668 0.5187 0.5242 0.5195 0.0 4n22:A, 4n24:A, 4n26:A, 4n28:A, 4n2a:A, 4n2b:A, 4n2c:A, 4n2e:A, 4n2g:A, 4n2l:A, 4n2m:A, 4n2n:A
6 8god:A 588 662 0.5277 0.6003 0.5332 0.0
7 4n20:A 639 668 0.5097 0.5336 0.5105 0.0 4n25:A, 4n2d:A, 4n2f:A, 4n2h:A, 4n2k:A
8 8sml:A 570 661 0.5172 0.6070 0.5234 0.0 8smk:A, 8smk:D, 8sml:D
9 4x8c:A 554 662 0.5022 0.6065 0.5076 0.0
10 8hjo:B 440 50 0.0194 0.0295 0.2600 4.0 8hjf:A, 8hjf:B, 8hjg:A, 8hjg:B, 8hjh:A, 8hjh:B, 8hjk:A, 8hjl:A, 8hjl:B, 8hjn:A, 8hjn:B, 8hjo:A, 8hjp:A, 8hjp:B, 8j66:A
11 2ocp:A 229 65 0.0359 0.1048 0.3692 4.1 2ocp:B, 2ocp:C, 2ocp:D, 2ocp:E, 2ocp:F, 2ocp:G, 2ocp:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218