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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HHHMLHLLEQIRAYCETCWEWQEAHNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTN
DHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVK
ALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNE
DHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLM
ANRPAKYKDAN

The query sequence (length=331) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5iz8:A 343 339 1.0000 0.9650 0.9764 0.0 5b6g:A, 7f6m:A, 7f7o:A, 8gsj:A, 5iz6:A, 5iz8:B, 5iz9:A, 5iza:A, 3nmx:A, 3nmx:B, 3nmx:C, 3qhe:A, 3qhe:C, 4yje:A, 4yjl:A, 4yjl:C, 4yjl:D, 4yjl:E, 4yjl:B, 4yjl:F, 4yk6:A, 5z8h:A
2 6s9o:F 343 275 0.2205 0.2128 0.2655 3.70e-04 5aei:A, 5aei:B, 5aei:C, 5mfd:A, 5mfd:C, 5mfd:E, 5mfd:I, 5mfd:G, 5mfd:J, 5mfd:K, 5mfd:L, 5mfe:A, 5mfe:B, 5mfe:C, 5mfe:D, 5mff:A, 5mff:B, 5mff:C, 5mff:D, 5mfg:A, 5mfh:A, 5mfh:B, 5mfh:C, 5mfh:D, 5mfl:A, 5mfl:B, 5mfl:C, 5mfm:A, 5mfm:B, 5mfm:C, 5mfm:E, 5mfm:D, 5mfm:F, 5mfn:B, 5mfn:A, 5mfo:A, 5mfo:C, 5mfo:E, 6s9l:A, 6s9l:B, 6s9m:A, 6s9m:E, 6s9m:B, 6s9m:C, 6s9m:D, 6s9m:F, 6s9n:A, 6s9n:E, 6s9n:B, 6s9n:C, 6s9n:F, 6s9n:D, 6s9o:A, 6s9o:B, 6s9o:C, 6s9o:D, 6s9o:E
3 6s9o:F 343 91 0.0755 0.0729 0.2747 0.19 5aei:A, 5aei:B, 5aei:C, 5mfd:A, 5mfd:C, 5mfd:E, 5mfd:I, 5mfd:G, 5mfd:J, 5mfd:K, 5mfd:L, 5mfe:A, 5mfe:B, 5mfe:C, 5mfe:D, 5mff:A, 5mff:B, 5mff:C, 5mff:D, 5mfg:A, 5mfh:A, 5mfh:B, 5mfh:C, 5mfh:D, 5mfl:A, 5mfl:B, 5mfl:C, 5mfm:A, 5mfm:B, 5mfm:C, 5mfm:E, 5mfm:D, 5mfm:F, 5mfn:B, 5mfn:A, 5mfo:A, 5mfo:C, 5mfo:E, 6s9l:A, 6s9l:B, 6s9m:A, 6s9m:E, 6s9m:B, 6s9m:C, 6s9m:D, 6s9m:F, 6s9n:A, 6s9n:E, 6s9n:B, 6s9n:C, 6s9n:F, 6s9n:D, 6s9o:A, 6s9o:B, 6s9o:C, 6s9o:D, 6s9o:E
4 6kbn:C 504 276 0.2205 0.1448 0.2645 0.002 6kbm:A, 6kbn:A
5 6kbn:C 504 170 0.1329 0.0873 0.2588 0.096 6kbm:A, 6kbn:A
6 6kbn:C 504 84 0.0634 0.0417 0.2500 0.20 6kbm:A, 6kbn:A
7 3l6x:A 434 256 0.1934 0.1475 0.2500 0.002 3l6y:A, 3l6y:C, 3l6y:E
8 4bqk:A 424 236 0.1722 0.1344 0.2415 0.025 4b8o:A, 4b8p:A, 4b8p:B, 4bpl:A, 4bqk:B, 2yns:A, 2yns:B
9 6ro8:A 413 78 0.0634 0.0508 0.2692 4.0
10 8fru:Y 135 51 0.0453 0.1111 0.2941 4.1 8br8:LZ, 8brm:LZ, 8bsi:LZ, 8bsj:LZ, 8btd:LZ, 8btr:LZ, 7pwg:Y, 7pwo:Y2
11 5ksw:B 262 108 0.0906 0.1145 0.2778 4.9 5ksw:D, 5ue9:B, 5ue9:D
12 8hn3:A 80 63 0.0634 0.2625 0.3333 6.9 8hn3:B
13 6qhd:B 532 115 0.0997 0.0620 0.2870 9.3
14 7dvq:K 188 119 0.0846 0.1489 0.2353 9.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218