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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HHHHHSDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSD
RVWIIDPLDGTREFSTPGRDDWAVHIALWRRPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIAVSATRPPAVL
HRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPDLLMC
RAEVAPILLGAIADAWR

The query sequence (length=257) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5djj:A 257 257 1.0000 1.0000 1.0000 0.0 5djg:A, 5djh:A, 5dji:A, 5djk:A
2 2p3n:A 256 197 0.1984 0.1992 0.2589 3.85e-06 2p3n:B, 2p3n:C, 2p3n:D
3 2wef:A 303 164 0.1790 0.1518 0.2805 4.72e-06 1jp4:A
4 5dw8:A 260 196 0.1868 0.1846 0.2449 6.89e-06 5dw8:B, 5j16:A, 5j16:B, 5j16:C, 5j16:D
5 6giu:A 275 240 0.2335 0.2182 0.2500 2.51e-05 4as4:A, 4as4:B, 1awb:A, 1awb:B, 6giu:B, 6gj0:A, 6gj0:B, 2hhm:A, 2hhm:B, 1ima:A, 1ima:B, 1imb:A, 1imb:B, 1imc:A, 1imc:B, 1imd:A, 1imd:B, 1ime:A, 1ime:B, 6zk0:AAA, 6zk0:BBB
6 4qxd:B 289 146 0.1440 0.1280 0.2534 1.31e-04 4qxd:A
7 5zon:A 256 64 0.1051 0.1055 0.4219 1.39e-04 5yht:A, 5yht:B, 5zon:B, 5zon:C, 5zon:D
8 8wdq:A 273 198 0.2374 0.2234 0.3081 1.88e-04 8wdq:B
9 3lv0:A 258 78 0.1012 0.1008 0.3333 1.98e-04 3luz:A, 3lv0:B
10 2bji:A 274 237 0.2179 0.2044 0.2363 7.28e-04 2bji:B
11 5eq9:B 260 107 0.1245 0.1231 0.2991 0.002 5eq8:A, 5eq9:A, 5eq9:C, 5eq9:D, 5t3j:A
12 2czi:A 259 250 0.2451 0.2432 0.2520 0.003 2czh:B
13 3luz:B 234 78 0.1012 0.1111 0.3333 0.004
14 4as5:A 274 210 0.1868 0.1752 0.2286 0.012 4as5:B, 4as5:C, 4as5:D
15 6ib8:B 270 87 0.0973 0.0926 0.2874 0.014 6ib7:A, 6ib8:A, 2qfl:A, 6tqn:T, 6tqn:S, 6tqo:T, 6tqo:S
16 8f9y:A 352 220 0.2062 0.1506 0.2409 0.026
17 5eyg:B 265 195 0.1518 0.1472 0.2000 0.060 5eyg:A, 5eyh:A, 5eyh:B, 5f24:A, 5f24:B, 4g61:A, 4g61:B, 4i3e:A, 4i3e:B, 4i3y:A, 4i3y:B, 4i40:A, 4i40:B, 4ptk:A, 4ptk:B, 3ryd:A, 3ryd:C
18 5q0c:A 328 50 0.0700 0.0549 0.3600 0.21 5et6:A, 5et6:C, 5et6:B, 5et6:D, 4he0:A, 4he1:A, 4he2:A, 3ifa:A, 3ifa:B, 3ifa:C, 3ifa:D, 3ifc:A, 3ifc:B, 3ifc:C, 3ifc:D, 5k56:A, 5l0a:A, 5q0c:B, 5q0c:C, 5q0c:D, 5q0c:E, 5q0c:F, 5q0c:G, 5q0c:H
19 5k55:A 290 49 0.0700 0.0621 0.3673 0.24 5et8:A
20 6c4m:C 418 84 0.1012 0.0622 0.3095 0.37
21 4hxv:A 317 176 0.1556 0.1262 0.2273 0.58 4o7i:A
22 1k9y:A 354 45 0.0661 0.0480 0.3778 5.1 1k9z:A, 1ka0:A, 1ka1:A, 1qgx:A
23 1otw:A 255 41 0.0623 0.0627 0.3902 5.7 3hlx:A, 3hlx:D, 3hml:A, 3hml:B, 3hnh:A, 4ny7:A, 4ny7:B, 1otw:B
24 6sup:A 2128 86 0.0778 0.0094 0.2326 7.0
25 7l3o:B 401 120 0.1323 0.0848 0.2833 8.0 7l3o:A, 7l3o:C, 7l3o:D
26 4o48:A 298 23 0.0506 0.0436 0.5652 9.2 4o48:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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