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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HHHHGSKFCRFGQRGQEKPGIIDADGNIRDLSGVVPELTIDALAAAKGADIALLPLVEGEPRYGVPVKGIGKIVAIGLNY
EDHAIESNLPIPTEPMMFMKALSSLNGPNDEVVLPKNSTHGDWEVELGVVIGETCRFVSEDEALSKVAGYVLVNDVSERF
NQKQRGTQWSKGKGHDTFCPVGPWLVTPDEVGDPQDLDVHLDVNGERMQTGNTKTMIFNVAQLISYVSEYITLYPGDLMI
TGTPPGVGEGKKPQAIYLKAGDVMELGIEKLGTQRQQVSEWRHLGDEVFG

The query sequence (length=290) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8gsr:A 290 290 1.0000 1.0000 1.0000 0.0 8gsr:B, 8gsr:C, 8gsr:D, 8gst:A, 8gst:B, 8gst:C, 8gst:D
2 6v77:B 279 215 0.3310 0.3441 0.4465 2.51e-50 6v77:A
3 3qdf:A 252 207 0.2931 0.3373 0.4106 1.93e-46
4 6iym:A 277 279 0.3586 0.3755 0.3728 3.26e-45 6iym:B
5 3r6o:A 265 218 0.2862 0.3132 0.3807 4.53e-44
6 8sky:B 303 209 0.3000 0.2871 0.4163 7.01e-43 8sky:A, 8sut:A, 8sut:B, 8suu:A, 8suu:B
7 6fog:A 218 211 0.2690 0.3578 0.3697 3.23e-38 6fog:C, 6fog:G, 6fog:E, 6fog:F, 6fog:H, 6fog:D, 6fog:B, 6foh:A, 6foh:B, 1saw:A, 1saw:B
8 6sbi:A 216 209 0.2690 0.3611 0.3732 4.54e-37 6sbi:B, 6sbi:C, 6sbi:D, 6sbj:A, 6sbj:B, 6sbj:C, 6sbj:D
9 6j5x:A 280 205 0.2517 0.2607 0.3561 5.49e-37 6j5x:B
10 1gtt:A 421 178 0.2448 0.1686 0.3989 7.18e-34 1gtt:B, 1gtt:C, 1gtt:D, 1i7o:A, 1i7o:B, 1i7o:C, 1i7o:D
11 1gtt:A 421 121 0.1448 0.0998 0.3471 2.69e-14 1gtt:B, 1gtt:C, 1gtt:D, 1i7o:A, 1i7o:B, 1i7o:C, 1i7o:D
12 6jvw:B 264 235 0.2828 0.3106 0.3489 1.89e-32 6jvw:A
13 4dbh:A 269 214 0.2690 0.2900 0.3645 2.48e-32 4dbf:A, 4dbf:B, 4dbh:B
14 1nr9:A 211 182 0.2241 0.3081 0.3571 7.29e-32 1nr9:B, 1nr9:C, 1nr9:D
15 3v77:A 224 188 0.2241 0.2902 0.3457 2.03e-29 3v77:B, 3v77:C, 3v77:D, 3v77:E, 3v77:F
16 6j5y:A 233 187 0.2034 0.2532 0.3155 6.86e-24
17 1nkq:A 247 216 0.2241 0.2632 0.3009 1.55e-19 1nkq:B, 1nkq:C, 1nkq:D, 1nkq:E, 1nkq:F
18 3lzk:C 343 160 0.1621 0.1370 0.2938 9.59e-12 3lzk:A, 3lzk:B, 3lzk:D
19 3bqb:X 291 197 0.1828 0.1821 0.2690 2.59e-08 3bqb:A, 3bqb:Z, 3bqb:Y, 2q1a:X, 2q1c:X, 2q1d:X
20 1hyo:B 419 202 0.1690 0.1169 0.2426 0.003 1hyo:A, 2hzy:A, 2hzy:B, 1qcn:A, 1qcn:B, 1qco:A, 1qco:B, 1qqj:A, 1qqj:B
21 3rsj:A 406 62 0.0655 0.0468 0.3065 1.5 3rsj:B, 3rsj:C, 3rsj:D
22 8j43:A 285 53 0.0586 0.0596 0.3208 3.5 8j43:B
23 8abs:A 394 27 0.0483 0.0355 0.5185 7.6 8abr:A, 5ofq:A, 5ofq:B, 5ofq:C, 5ofq:D
24 6dmh:A 270 63 0.0690 0.0741 0.3175 8.7 4euz:A, 4ev4:A
25 3zrq:A 382 59 0.0621 0.0471 0.3051 8.8 3zrp:A, 3zrp:B, 3zrq:B, 3zrr:A, 3zrr:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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