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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HHGSKKPINVAIFGSTGSIGTNALNIIRECNKIENVFNVKALYVNKSVNELYEQAREFLPEYLCIHDKSVYEELKELVKN
IKDYKPIILCGDEGMKEICSSNSIDKIVIGIDSFQGLYSTMYAIMNNKIVALANKESIVSAGFFLKKLLNIHKNAKIIPV
DSEHSAIFQCLDNNKVIKTKCLQDNFSKINNINKIFLCSSGGPFQNLTMDELKNVTSENALKHPKWKMGKKITIDSATMM
NKGLEVIETHFLFDVDYNDIEVIVHKECIIHSCVEFIDKSVISQMYYPDMQIPILYSLTWPDRIKTNLKPLDLAQVSTLT
FHKPSLEHFPCIKLAYQAGIKGNFYPTVLNASNEIANNLFLNNKIKYFDISSIISQVLESFNSQKVSENSEDLMKQILQI
HSWAKDKATDIYNKHN

The query sequence (length=416) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4gae:A 416 416 1.0000 1.0000 1.0000 0.0 3au8:A, 3au8:B, 3au9:A, 3au9:B, 3aua:A, 3aua:B, 4gae:B, 5jaz:A, 5jaz:B, 5jbi:A, 5jbi:B, 5jc1:A, 5jc1:B, 5jmp:A, 5jmp:B, 5jmw:A, 5jmw:B, 5jnl:A, 5jnl:B, 8jnv:A, 8jnv:B, 8jnw:A, 8jnw:B, 5jo0:A, 5jo0:B, 4kp7:A, 4kp7:B, 3wqq:A, 3wqq:B, 3wqr:A, 3wqr:B, 3wqs:B, 4y67:A, 4y67:B, 4y6p:A, 4y6p:B, 4y6r:A, 4y6r:B, 4y6s:A, 4y6s:B
2 8s65:B 411 416 0.3990 0.4039 0.3990 3.53e-101 8s65:A
3 7s04:A 396 375 0.3582 0.3763 0.3973 7.76e-91
4 4zqg:A 408 396 0.3726 0.3799 0.3914 3.13e-88 4zqf:A, 4zqf:B, 4zqg:B, 4zqh:A, 4zqh:B
5 6mh5:B 375 403 0.3798 0.4213 0.3921 7.93e-88 6mh5:A
6 3anl:A 400 381 0.3413 0.3550 0.3727 2.11e-86 3anl:B, 3anm:A, 3anm:B, 3ann:A, 3ann:B, 2egh:A, 2egh:B, 1jvs:A, 1jvs:B, 1ono:A, 1ono:B, 1onp:A, 1onp:B, 1q0h:A, 1q0l:A, 1q0q:A, 1q0q:B, 3r0i:A, 3r0i:B, 1t1r:A, 1t1r:B, 1t1s:A, 1t1s:B
7 5kqo:A 398 374 0.3413 0.3568 0.3797 4.16e-83 5kqo:B, 5krr:A, 5krr:B, 5ks1:A, 5ks1:B
8 1r0l:B 379 383 0.3317 0.3641 0.3603 6.99e-81 1r0l:A, 1r0l:C, 1r0l:D
9 5dul:B 390 409 0.3462 0.3692 0.3521 1.50e-77 5dul:A, 5dul:D, 3iie:A, 3iie:B
10 4aic:A 379 402 0.3221 0.3536 0.3333 3.62e-72 4a03:A, 4a03:B, 4aic:B, 2c82:A, 2c82:B, 2jcv:A, 2jcv:B, 2jcx:A, 2jcx:B, 2jd0:A, 2jd1:A, 2jd1:B, 2jd2:A, 2jd2:B, 4ooe:A, 4ooe:B, 4ooe:C, 4ooe:D, 4oof:A, 4oof:B, 3ras:A, 3ras:B, 4rcv:A, 4rcv:B, 2y1c:A, 2y1c:B, 2y1d:B, 2y1e:A, 2y1e:B, 2y1f:A, 2y1f:B, 2y1g:A, 2y1g:B, 3zhx:A, 3zhx:B, 3zhy:A, 3zhy:B, 3zhz:A, 3zi0:A, 3zi0:B
11 5dul:C 367 407 0.3245 0.3678 0.3317 2.81e-64
12 2y1d:A 359 401 0.3173 0.3677 0.3292 3.38e-62
13 3a06:B 373 404 0.3029 0.3378 0.3119 2.98e-60 3a06:A, 3a14:A, 3a14:B
14 8ssk:D 306 57 0.0481 0.0654 0.3509 0.24 8ssk:A, 8ssk:B, 8ssk:C
15 8xku:C 921 75 0.0601 0.0271 0.3333 0.97 8xkv:C
16 2r00:C 336 21 0.0264 0.0327 0.5238 2.1
17 3jsa:A 321 51 0.0481 0.0623 0.3922 2.7
18 2vn4:A 599 62 0.0337 0.0234 0.2258 3.4 2vn7:A
19 3szj:A 120 30 0.0288 0.1000 0.4000 7.1 3szj:B, 3t2w:A
20 2dm6:B 333 66 0.0481 0.0601 0.3030 8.6 2dm6:A, 1v3t:A, 1v3t:B, 1v3v:A, 1v3v:B
21 5kdr:A 301 30 0.0288 0.0399 0.4000 8.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218