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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HGYVSAVENGVAEGRVTLCKFAANGTGEKNTHCGAIQYEPQSVEGPDGFPVTGPRDGKIASAESALAAALDEQTADRWVK
RPIQAGPQTFEWTFTANHVTKDWKYYITKPNWNPNQPLSRDAFDLNPFCVVEGNMVQPPKRVSHECIVPEREGYQVILAV
WDVGDTAASFYNVIDVKFDG

The query sequence (length=180) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8cc3:A 180 180 1.0000 1.0000 1.0000 1.00e-135 8cc3:B, 8cc5:A, 8cc5:B, 7pb6:A, 7pb6:B, 7pb7:A, 7pb7:B
2 8gul:B 361 180 0.8444 0.4211 0.8444 1.68e-114
3 8gul:A 464 180 0.8444 0.3276 0.8444 1.89e-112
4 8rry:A 170 179 0.4778 0.5059 0.4804 3.77e-57 8rry:B
5 5wsz:A 169 179 0.5000 0.5325 0.5028 6.73e-53 5wsz:B, 5wsz:C, 5wsz:D
6 6t5z:A 174 177 0.4444 0.4598 0.4520 2.96e-50 6t5z:B, 6t5z:C
7 5iju:A 178 149 0.4278 0.4326 0.5168 4.17e-48 5iju:B, 2yox:A, 2yox:B, 2yoy:A, 2yoy:B
8 6twe:A 172 165 0.4222 0.4419 0.4606 8.83e-47
9 5l2v:A 166 179 0.4278 0.4639 0.4302 8.68e-45 5l2v:B
10 5ftz:A 172 151 0.4111 0.4302 0.4901 3.27e-42
11 4alc:A 166 179 0.4167 0.4518 0.4190 4.24e-38 4ale:A, 4alq:A, 4alr:A, 4als:A, 4alt:A
12 7zjb:B 181 123 0.2167 0.2155 0.3171 2.75e-14
13 5fjq:A 180 192 0.3333 0.3333 0.3125 2.63e-13 5fjq:B, 5fjq:C
14 5aa7:A 142 176 0.2833 0.3592 0.2898 4.63e-11 5aa7:B, 5vg0:A, 5vg0:B, 5vg1:A, 5vg1:B
15 6rw7:A 208 124 0.2111 0.1827 0.3065 1.22e-06
16 6if7:A 183 129 0.1889 0.1858 0.2636 2.41e-06
17 7okr:AAA 192 130 0.2000 0.1875 0.2769 6.76e-04
18 4oy7:A 196 83 0.1333 0.1224 0.2892 7.53e-04 4oy7:B, 4oy7:C, 4oy7:D, 4oy7:E, 4oy7:F, 4oy7:G, 4oy7:H
19 5uiz:A 186 84 0.1222 0.1183 0.2619 0.004
20 7aat:A 401 78 0.1333 0.0599 0.3077 0.035 7aat:B, 8aat:A, 8aat:B, 9aat:A, 9aat:B, 1aka:A, 1aka:B, 1akb:A, 1akc:A, 1ama:A, 1ivr:A, 1map:A, 1maq:A, 1oxo:A, 1oxo:B, 1oxp:A, 1tar:A, 1tar:B, 1tas:A, 1tas:B, 1tat:A, 1tat:B
21 7rh5:c 158 86 0.1556 0.1772 0.3256 0.095 6adq:K, 6adq:W, 8ovc:W, 8ovc:b, 8ovd:b, 8ovd:W, 7rh5:W, 7rh6:c, 7rh7:W, 7rh7:c
22 5uzx:A 231 59 0.0889 0.0693 0.2712 0.10 5uzx:B
23 1ug9:A 1019 58 0.1167 0.0206 0.3621 0.20 1ulv:A
24 7r27:B 398 64 0.1333 0.0603 0.3750 0.51 7r27:A
25 4yn2:A 281 106 0.1444 0.0925 0.2453 0.65
26 8urb:A 921 46 0.0889 0.0174 0.3478 1.2 8g6r:A
27 2f02:A 319 36 0.0667 0.0376 0.3333 1.6 2f02:B
28 3o3m:C 401 29 0.0722 0.0324 0.4483 4.3 3o3m:A, 3o3n:A, 3o3n:C, 3o3o:A
29 5v1b:A 226 40 0.0722 0.0575 0.3250 4.7
30 8skr:A 402 78 0.1167 0.0522 0.2692 6.1 3pd6:A, 3pd6:B, 3pd6:C, 3pdb:B, 3pdb:D, 8skr:C
31 6h7f:A 671 109 0.1389 0.0373 0.2294 6.5 6h7f:B, 6h7f:C, 6h7v:B, 6hcp:A, 6hcp:B, 6hcp:C
32 1u63:A 214 36 0.0667 0.0561 0.3333 8.1 1i2a:A, 1u63:C
33 5k1r:B 440 89 0.1333 0.0545 0.2697 8.7 5k1r:A
34 5eke:C 307 47 0.0889 0.0521 0.3404 8.8 5eke:A, 5eke:B, 5eke:D, 5ekp:C, 5ekp:A, 5ekp:B, 5ekp:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218