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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HGKRYRALLEKVDPNKIYTIDEAAHLVKELATAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGFRNDKTGAIHAPV
GKASFPPEKLADNIRAFIRALEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS

The query sequence (length=133) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2vpl:A 137 135 0.9850 0.9562 0.9704 2.93e-92 5e7k:71, 5e81:71, 5el4:71, 5el5:71, 5el6:71, 5el7:71, 6gsl:71, 6gsl:79, 5hau:1C, 5hau:2C, 5ib7:71, 5ib8:71, 5ibb:71, 5j8b:C, 6qnq:71, 6qnr:71, 6qnr:79, 4v4i:A, 4v4j:A, 2vpl:C, 4wpo:AC, 4wpo:CC, 4wqf:AC, 4wqf:CC, 4wqu:AC, 4wqu:CC, 4wqy:AC, 4wqy:CC, 4wu1:71, 4wu1:79, 4wzd:71, 4wzd:79
2 6c5l:BC 120 133 0.8722 0.9667 0.8722 1.07e-78 6c5l:DC, 4v5j:BC, 4v5j:DC, 4v7j:AC, 4v7j:BC, 4v7k:AC, 4v7k:BC, 4v8n:BC, 4v8n:DC, 4v8x:BC, 4v8x:DC
3 4wzo:71 93 129 0.6992 1.0000 0.7209 7.68e-53
4 6bu8:03 134 131 0.5113 0.5075 0.5191 2.52e-43 7jsz:a, 7jt3:a, 7k50:a, 7k51:a, 7k52:a, 7k53:a, 7k54:a, 7k55:a, 7lv0:a, 7n2c:LA, 6ofx:a, 6og7:a, 6ogf:a, 6ogg:a, 6ogi:a, 8peg:a, 8pkl:a, 7qg8:C, 7qgh:C, 7qgn:C, 7qgr:C, 8r3v:a2, 8rcl:a2, 8rcm:a2, 7ss9:a, 7ssd:a, 7ssl:a, 7sso:a, 7ssw:a, 7st2:a, 7st7:a, 7tos:L1, 7ug7:LA, 5uyl:03, 5uym:03, 5uyn:03, 5uyp:03, 5uyq:03, 8vs9:L1, 8vsa:L1, 6wd0:a, 6wd1:a, 6wd2:a, 6wd3:a, 6wd4:a, 6wd5:a, 6wd6:a, 6wd7:a, 6wd8:a, 6wd9:a, 6wda:a, 6wdb:a, 6wdc:a, 6wdd:a, 6wde:a, 6wdf:a, 6wdg:a, 6wdh:a, 6wdi:a, 6wdj:a, 6wdk:a, 6wdl:a, 6wdm:a, 6wnt:a, 6wnv:a, 6wnw:a
5 4qvi:A 229 67 0.5038 0.2926 1.0000 3.55e-42 7a5f:n, 7a5g:n, 7a5j:n, 5a9z:AC, 5aa0:AC, 2hw8:A, 5imq:Z, 5imr:Z, 7lh5:BC, 7lh5:DC, 6n1d:AL01, 6n1d:BL01, 5npm:A, 2om7:K, 5ot7:f, 6q95:A, 4qg3:A, 4reo:A, 4u1u:B5, 4u1v:B5, 4u20:B5, 4u24:B5, 4u25:B5, 4u26:B5, 4u27:B5, 3u4m:A, 3u56:A, 3umy:A, 5uq7:C, 5uq8:C, 4v4p:AC, 4v4x:BC, 4v4y:BC, 4v4z:BC, 4v51:BC, 4v51:DC, 4v5a:BC, 4v5a:DC, 4v5c:BC, 4v5c:DC, 4v5d:BC, 4v5d:DC, 4v5e:BC, 4v5e:DC, 4v5f:BC, 4v5f:DC, 4v5g:BC, 4v5g:DC, 4v5k:BC, 4v5k:DC, 4v5l:BC, 4v5m:BC, 4v5n:BC, 4v5p:BC, 4v5p:DC, 4v5q:BC, 4v5q:DC, 4v5r:BC, 4v5r:DC, 4v5s:BC, 4v5s:DC, 4v68:BC, 4v6a:BC, 4v6a:DC, 4v7l:BC, 4v7l:DC, 4v7m:BC, 4v7m:DC, 4v8j:BC, 4v8j:DC, 4v8o:BC, 4v8q:AC, 4v8u:BC, 4v8u:DC, 4v8y:By, 4v8y:CL, 4v90:BC, 4v97:BC, 4v97:DC, 4v9h:BC, 4v9j:BC, 4v9j:DC, 4v9k:BC, 4v9k:DC, 4v9l:BC, 4v9l:DC, 4v9m:BC, 4v9m:DC, 4w29:BC, 4w29:DC, 4wf1:B5, 4woi:B5, 1zho:A, 1zho:C, 1zho:E, 1zho:G, 5zlu:Y
6 4qvi:A 229 66 0.4887 0.2838 0.9848 1.50e-41 7a5f:n, 7a5g:n, 7a5j:n, 5a9z:AC, 5aa0:AC, 2hw8:A, 5imq:Z, 5imr:Z, 7lh5:BC, 7lh5:DC, 6n1d:AL01, 6n1d:BL01, 5npm:A, 2om7:K, 5ot7:f, 6q95:A, 4qg3:A, 4reo:A, 4u1u:B5, 4u1v:B5, 4u20:B5, 4u24:B5, 4u25:B5, 4u26:B5, 4u27:B5, 3u4m:A, 3u56:A, 3umy:A, 5uq7:C, 5uq8:C, 4v4p:AC, 4v4x:BC, 4v4y:BC, 4v4z:BC, 4v51:BC, 4v51:DC, 4v5a:BC, 4v5a:DC, 4v5c:BC, 4v5c:DC, 4v5d:BC, 4v5d:DC, 4v5e:BC, 4v5e:DC, 4v5f:BC, 4v5f:DC, 4v5g:BC, 4v5g:DC, 4v5k:BC, 4v5k:DC, 4v5l:BC, 4v5m:BC, 4v5n:BC, 4v5p:BC, 4v5p:DC, 4v5q:BC, 4v5q:DC, 4v5r:BC, 4v5r:DC, 4v5s:BC, 4v5s:DC, 4v68:BC, 4v6a:BC, 4v6a:DC, 4v7l:BC, 4v7l:DC, 4v7m:BC, 4v7m:DC, 4v8j:BC, 4v8j:DC, 4v8o:BC, 4v8q:AC, 4v8u:BC, 4v8u:DC, 4v8y:By, 4v8y:CL, 4v90:BC, 4v97:BC, 4v97:DC, 4v9h:BC, 4v9j:BC, 4v9j:DC, 4v9k:BC, 4v9k:DC, 4v9l:BC, 4v9l:DC, 4v9m:BC, 4v9m:DC, 4w29:BC, 4w29:DC, 4wf1:B5, 4woi:B5, 1zho:A, 1zho:C, 1zho:E, 1zho:G, 5zlu:Y
7 5dm6:0 224 65 0.4060 0.2411 0.8308 2.32e-31 5dm7:0
8 5dm6:0 224 60 0.2932 0.1741 0.6500 3.43e-21 5dm7:0
9 3j3v:5 120 132 0.4135 0.4583 0.4167 1.88e-30 3j3w:5
10 7nhk:F 132 130 0.3985 0.4015 0.4077 9.46e-30
11 8v9j:K 102 94 0.3459 0.4510 0.4894 1.78e-26 8v9k:K
12 4v9i:BC 190 52 0.3308 0.2316 0.8462 5.24e-23 4v9i:DC, 4wt8:CA, 4wt8:DA
13 5ady:5 234 65 0.3083 0.1752 0.6308 1.06e-20 4csu:5, 6dnc:E, 6enj:7, 6enu:7, 3j46:5, 3j5s:F, 3j8g:5, 3j9z:LC, 3ja1:LC, 3jcd:5, 3jce:5, 8rcs:a2, 8rct:a2, 5u9f:03, 5u9g:03, 5uyk:03, 4v4v:B2, 4v4w:B2, 4v5h:B5, 4v69:B5, 4v6k:AC, 4v6l:BC, 4v6m:B5, 4v6n:AC, 4v6o:BC, 4v6p:BC, 4v6q:BC, 4v6r:BC, 4v6s:AC, 4v6v:BC, 4v6y:B5, 4v6z:B5, 4v70:B5, 4v71:B5, 4v72:B5, 4v73:B5, 4v74:B5, 4v75:B5, 4v76:B5, 4v77:B5, 4v78:B5, 4v79:B5, 4v7a:B5, 4v7c:BC, 4v7d:AC, 4v7i:A5
14 5ady:5 234 63 0.2030 0.1154 0.4286 1.55e-13 4csu:5, 6dnc:E, 6enj:7, 6enu:7, 3j46:5, 3j5s:F, 3j8g:5, 3j9z:LC, 3ja1:LC, 3jcd:5, 3jce:5, 8rcs:a2, 8rct:a2, 5u9f:03, 5u9g:03, 5uyk:03, 4v4v:B2, 4v4w:B2, 4v5h:B5, 4v69:B5, 4v6k:AC, 4v6l:BC, 4v6m:B5, 4v6n:AC, 4v6o:BC, 4v6p:BC, 4v6q:BC, 4v6r:BC, 4v6s:AC, 4v6v:BC, 4v6y:B5, 4v6z:B5, 4v70:B5, 4v71:B5, 4v72:B5, 4v73:B5, 4v74:B5, 4v75:B5, 4v76:B5, 4v77:B5, 4v78:B5, 4v79:B5, 4v7a:B5, 4v7c:BC, 4v7d:AC, 4v7i:A5
15 5e7k:79 57 117 0.4135 0.9649 0.4701 1.16e-19 5e81:79, 5el6:79, 5el7:79, 5ibb:79
16 7msc:8 230 65 0.2782 0.1609 0.5692 1.52e-17 7msh:8, 7msm:8, 7msz:8, 7mt2:8, 7mt3:8, 7mt7:8
17 7msc:8 230 67 0.1955 0.1130 0.3881 2.76e-09 7msh:8, 7msm:8, 7msz:8, 7mt2:8, 7mt3:8, 7mt7:8
18 4v61:BD 227 63 0.2256 0.1322 0.4762 2.55e-16
19 4v61:BD 227 65 0.1955 0.1145 0.4000 2.32e-10
20 7p7q:F 226 65 0.2406 0.1416 0.4923 6.29e-16 7p7r:F, 7p7s:F, 7p7t:F
21 7p7q:F 226 66 0.2105 0.1239 0.4242 1.37e-12 7p7r:F, 7p7s:F, 7p7t:F
22 6ha8:8 212 53 0.2256 0.1415 0.5660 3.28e-14
23 6ha8:8 212 66 0.2105 0.1321 0.4242 1.47e-13
24 8fmw:AC 221 96 0.2406 0.1448 0.3333 2.71e-12
25 8fmw:AC 221 62 0.1880 0.1131 0.4032 6.00e-09
26 4v4n:AA 216 54 0.1729 0.1065 0.4259 1.93e-06 4v6u:BA
27 6ywx:e 150 98 0.2256 0.2000 0.3061 6.82e-06 6ywy:e
28 6ywe:e 242 78 0.1579 0.0868 0.2692 2.61e-04 6yws:e
29 4d5y:u 210 83 0.1880 0.1190 0.3012 2.76e-04 4d67:u, 4ujc:Bu, 4ujd:Au, 4uje:Cu, 4v5z:B5
30 8brm:Ln 211 58 0.1353 0.0853 0.3103 6.38e-04 8br8:Ln, 8bsi:Ln, 8bsj:Ln, 8btd:Ln, 8btr:Ln
31 8oir:Bj 164 137 0.2256 0.1829 0.2190 8.73e-04 8oit:Bj, 7qi4:z
32 1mzp:A 217 54 0.1429 0.0876 0.3519 0.003 8hku:AL1P, 8hky:AL1P, 8hkz:AL1P, 8hl1:AL1P, 8hl2:AL1P, 8hl3:AL1P, 8hl4:AL1P, 8hl5:AL1P, 4v49:B5, 4v4a:B5, 4v4g:B7, 4v4g:D7, 4v4g:F7, 4v4g:H7, 4v4g:J7, 4v65:BZ, 4v66:BZ
33 8oin:Bj 164 137 0.2180 0.1768 0.2117 0.019 8oiq:Bj
34 1u63:A 214 51 0.1429 0.0888 0.3725 0.089 1i2a:A, 1u63:C
35 4v3p:LA 216 62 0.1203 0.0741 0.2581 0.71 4v7e:Cz
36 4v3p:LA 216 32 0.1128 0.0694 0.4688 2.5 4v7e:Cz
37 5jpq:k 182 41 0.1429 0.1044 0.4634 0.75 5oql:Q
38 8i9p:CB 269 41 0.1429 0.0706 0.4634 0.95 8i9r:CB, 8i9t:CB, 8i9v:CB, 8i9w:CB, 8i9x:CB, 8i9y:CB, 8i9z:CB, 8ia0:CB, 8pv1:CB, 8pv3:CB, 8pv4:CB, 8pv7:CB, 8pvk:CB, 6rxt:UZ, 6rxu:UZ, 6rxv:UZ, 6rxy:UZ, 6rxz:UZ
39 5khl:B 257 56 0.1504 0.0778 0.3571 1.6
40 1m32:B 362 53 0.1203 0.0442 0.3019 1.7 1m32:A, 1m32:C, 1m32:D, 1m32:E, 1m32:F
41 2oo4:A 226 17 0.0677 0.0398 0.5294 7.4 2oo4:B
42 3haz:A 983 48 0.1053 0.0142 0.2917 8.9 6bsn:A, 6bsn:B, 3haz:B, 4q71:A, 4q71:B, 4q72:A, 4q72:B, 4q73:A, 4q73:B
43 5w7c:C 420 53 0.1353 0.0429 0.3396 9.0 5w78:B, 5w7c:D
44 8any:z 252 73 0.1203 0.0635 0.2192 9.7 7a5k:n, 7qi5:z, 7qi6:z
45 4v8m:BJ 214 41 0.0977 0.0607 0.3171 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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