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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HGHMQTLIFLDLEATGLPSSRPEVTELCLLAVHRRALENTSISQGHPPPVPRPPRVVDKLSLCIAPGKACSPGASEITGL
SKAELEVQGRQRFDDNLAILLRAFLQRQPQPCCLVAHNGDRYDFPLLQTELARLSTPSPLDGTFCVDSIAALKALEQASS
KSYSLGSIYTRLYWQAPTDSHTAEGDVLTLLSICQWKPQALLQWVDEHARPFSTVKPMYG

The query sequence (length=220) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5yws:B 234 227 1.0000 0.9402 0.9692 2.49e-161 3b6o:A, 3b6o:B, 3b6o:C, 3b6o:D, 3b6p:A, 3b6p:B, 3b6p:C, 3b6p:D, 8hcc:A, 8hcc:B, 8hcc:C, 8hcc:D, 8hcd:B, 8hcd:C, 8hcd:D, 8hcd:E, 8hce:B, 8hcf:B, 8hcg:A, 8hch:A, 8hch:B, 8hch:C, 8hch:D, 2ioc:B, 2ioc:A, 3mxi:B, 3mxi:A, 3mxm:A, 3mxm:B, 2o4g:A, 2o4g:B, 2o4g:C, 2o4g:D, 2o4i:A, 2o4i:B, 2oa8:B, 2oa8:A, 3u3y:A, 3u3y:B, 3u6f:B, 3u6f:A, 7u8y:A, 7u8y:B, 4ynq:A, 4ynq:C, 4ynq:D, 4ynq:B, 5yws:A, 5ywt:B, 5ywt:A, 5ywu:A, 5ywu:B, 5ywv:A, 5ywv:B
2 8vl7:C 224 226 0.7727 0.7589 0.7522 1.49e-103 9ava:A, 9ava:B, 9ava:C, 9ava:D, 9ava:E, 9ava:F, 9ava:G, 9ava:H, 9ava:I, 9ava:J, 9ava:K, 9ava:L, 7tqq:A, 7tqq:B, 7tqq:E, 7tqq:F, 8vl7:A, 8vl7:B, 8vl7:D, 8vl7:E, 8vl7:F, 8vl7:G, 8vl7:H
3 6a47:A 224 217 0.4727 0.4643 0.4793 4.41e-59 6a46:A, 6a46:B, 6a47:B, 6a4b:B, 6a4b:A, 6a4b:C, 6a4b:D, 6a4b:E, 6a4b:F
4 3q2t:A 205 30 0.0545 0.0585 0.4000 0.72 3bho:A, 3mdg:A, 3mdi:A, 3p6y:A, 3p6y:B, 3p6y:E, 3p6y:I, 3p6y:M, 3p6y:N, 3p6y:F, 3q2t:B, 5r4p:A, 5r4p:B, 5r4q:A, 5r4q:B, 5r4r:A, 5r4r:B, 5r4s:A, 5r4s:B, 5r4t:A, 5r4t:B, 5r4u:A, 5r4u:B, 5r64:A, 5r64:B, 5r65:A, 5r65:B, 5r66:A, 5r66:B, 5r67:A, 5r67:B
5 4ail:C 750 37 0.0591 0.0173 0.3514 0.81 2jgu:A
6 3c9f:B 540 42 0.0682 0.0278 0.3571 2.6 3c9f:A
7 8dvv:A 3886 104 0.1364 0.0077 0.2885 3.2 8dvv:B, 8dvv:C, 8dvv:D
8 4flu:A 758 34 0.0500 0.0145 0.3235 4.8 4flt:A, 4flv:A, 4flw:A, 4flx:A, 4fly:A, 4flz:A, 4fm0:A, 4fm1:A, 4fm2:A
9 4k8x:A 759 37 0.0545 0.0158 0.3243 5.7 6is7:A, 6is7:B, 6isf:A, 6isf:B, 6isg:A, 6ish:A, 6isi:A, 4k8z:A, 5omf:A, 5omq:A, 5omv:A, 7om3:A, 7omb:A, 7omg:A, 6q4t:A, 7rsr:A, 7rss:A, 7rsu:A, 8t3x:A, 7tqw:A, 5vu6:A, 5vu7:A, 5vu9:A
10 3j9w:AC 210 138 0.1545 0.1619 0.2464 6.0 8buu:c, 8cdu:E, 8cec:H, 8ced:E, 8cee:E, 6ha1:c, 6ha8:c, 6htq:c, 5njt:C, 7o5b:C, 8qcq:c, 7qgu:h, 7qh4:g, 8qpp:C, 7qv1:c, 7qv2:c, 7qv3:c, 8r55:C
11 6jgz:B 3485 107 0.1273 0.0080 0.2617 7.5 6jg3:A, 6jg3:B, 6jg3:C, 6jg3:D, 6jgz:D, 6jgz:F, 6jgz:H, 6jh6:B, 6jh6:D, 6jh6:F, 6jh6:H, 6jhn:A, 6jhn:C, 6jhn:E, 6jhn:G, 6ji0:A, 6ji0:C, 6ji0:E, 6ji0:G, 6jrr:A, 6jrr:C, 6jrr:E, 6jrr:G
12 2x5d:D 380 74 0.0909 0.0526 0.2703 9.8 2x5d:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218