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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HGGTILVVTGTGTGVGKTVVCAALASAARQAGIDVAVCKPVQTGTARGDDDLAEVGRLAGVTQLAGLARYPQPMAPAAAA
EHAGMALPARDQIVRLIADLDRPGRLTLVEGAGGLLVELAEPGVTLRDVAVDVAAAALVVVTADLGTLNHTKLTLEALAA
QQVSCAGLVIGSWPDPPGLVAASNRSALARIAMVRAALPAGAASLDAGDFAAMSAAAFDRNWVAGLV

The query sequence (length=227) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3fmi:A 231 224 0.9868 0.9697 1.0000 6.37e-154 6cve:A, 6cve:B, 6cve:C, 6cve:D, 6cvf:A, 6cvf:B, 6cvf:C, 6cvf:D, 6cvu:A, 6cvu:B, 6cvu:C, 6cvu:D, 6cvv:A, 6cvv:B, 6cvv:C, 6cvv:D, 6czb:A, 6czb:B, 6czb:C, 6czb:D, 6czc:A, 6czc:B, 6czc:C, 6czc:D, 6czd:A, 6czd:B, 6czd:C, 6czd:D, 6cze:A, 6cze:B, 6cze:C, 6cze:D, 6e05:A, 6e05:B, 6e05:C, 6e05:D, 6e06:A, 6e06:B, 6e06:C, 6e06:D, 3fmf:A, 3fmf:B, 3fmf:C, 3fmf:D, 3fmi:B, 3fmi:C, 3fmi:D, 3fpa:A, 3fpa:B, 3fpa:C, 3fpa:D, 7jt5:A, 7jt5:B, 7jt5:C, 7jt5:D, 7jt6:A, 7jt6:B, 7jt6:C, 7jt6:D, 7l1j:A, 7l1j:B, 7l1j:C, 7l1j:D, 6nka:A, 6nka:B, 6nka:C, 6nka:D, 6nkb:A, 6nkb:B, 6nkb:C, 6nkb:D, 6nl4:A, 6nl4:B, 6nl4:D, 6nl5:A, 6nl5:B, 6nl5:C, 6nl5:D, 6nlz:A, 6nlz:B, 6nlz:C, 6nlz:D, 6nmz:A, 6nmz:B, 6nmz:C, 6nmz:D, 6nn0:A, 6nn0:B, 6nn0:C, 6nn0:D, 6nnz:A, 6nnz:B, 6nnz:C, 6nnz:D, 6nu6:A, 6nu6:B, 6nu6:C, 6nu6:D, 6nvc:A, 6nvc:B, 6nvc:C, 6nvc:D, 6nvd:D, 6nve:A, 6nve:B, 6nve:C, 6nve:D, 6nvf:A, 6nvf:B, 6nvf:C, 6nvf:D, 6nwg:A, 6nwg:B, 6nwg:D, 6nwn:A, 6nwn:B, 6nwn:C, 6nwn:D, 4wop:A, 4wop:C, 4wop:D
2 1a82:A 224 198 0.2731 0.2768 0.3131 9.17e-12 1bs1:A, 1dad:A, 1dae:A, 1daf:A, 1dag:A, 1dah:A, 1dai:A, 1dak:A, 1dam:A
3 3mle:B 224 171 0.1850 0.1875 0.2456 2.80e-08 3mle:A, 3mle:C, 3mle:D, 3mle:E, 3mle:F, 3qxc:A, 3qxh:A, 3qxj:A, 3qxs:A, 3qxx:A, 3qy0:A
4 9fvt:A 519 74 0.1101 0.0482 0.3378 0.10 9fvt:B, 9fvt:C, 9fvt:D
5 8auw:A 2900 73 0.0925 0.0072 0.2877 0.26
6 8atu:A 2837 73 0.0925 0.0074 0.2877 0.27 8atu:B, 8atx:A, 8atx:B, 8auk:A, 8auk:B, 8auw:B
7 3gp8:A 551 40 0.0661 0.0272 0.3750 1.2 3gpl:A, 3gpl:B
8 7t85:A 173 37 0.0573 0.0751 0.3514 2.9
9 1itw:A 740 88 0.1057 0.0324 0.2727 3.8 1itw:B, 1itw:C, 1itw:D, 1j1w:A, 1j1w:B, 1j1w:C, 1j1w:D
10 6d9y:B 251 60 0.0925 0.0837 0.3500 5.1
11 5twt:A 291 96 0.1233 0.0962 0.2917 8.2
12 6g2g:B 273 33 0.0749 0.0623 0.5152 8.9 6g2g:A
13 3la6:B 260 30 0.0485 0.0423 0.3667 9.0 3la6:A, 3la6:C, 3la6:D, 3la6:E, 3la6:F, 3la6:G, 3la6:H, 3la6:I, 3la6:J, 3la6:K, 3la6:L, 3la6:M, 3la6:N, 3la6:O, 3la6:P

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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