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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HGFVSGIVADGSYYGGYNTDEYPYMSNPPNVIAWSTTATNCGFTNGTGYQSPDIICHSNASNGSNTAVVAAGSSIQFQWT
VWPASHHGPLITYLAPCGGNCATVDKTTLDFTKIAAVGLVNGVSPPGVWADDSMIADNNTAVVVIPASYAPGNYVLRHEI
IALHVAGNNNGAQNYPQCFNIQITGGGSAQGSGVAGTSLYKNTDPGIKFNIYSDLSGGYPIPGPALFA

The query sequence (length=228) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7vfc:A 228 228 1.0000 1.0000 1.0000 1.22e-166
2 5x6a:A 229 227 0.8289 0.8253 0.8326 1.92e-140 6h1z:A, 6h1z:B, 6ha5:A, 6ha5:B, 6haq:A, 6haq:B, 5x6a:B
3 8b4g:AAA 228 227 0.6360 0.6360 0.6388 2.52e-104 7pu1:AAA, 7pu1:BBB, 7pz3:A, 7pz4:A, 7pz5:A, 7pz6:A, 7pz7:A, 7pz8:A, 7q1k:A, 2yet:A, 2yet:B, 3zud:A
4 7ova:DDD 231 228 0.6053 0.5974 0.6053 1.34e-101 7ova:AAA, 7ova:BBB, 7ova:CCC
5 7a8v:A 230 228 0.5833 0.5783 0.5833 1.20e-93
6 5o2w:A 248 228 0.5482 0.5040 0.5482 2.05e-81 5o2x:A
7 7ntl:A 220 227 0.4956 0.5136 0.4978 5.86e-71
8 2vtc:A 228 233 0.4561 0.4561 0.4464 5.73e-57 2vtc:B
9 5nns:A 225 182 0.3289 0.3333 0.4121 2.50e-35 5nns:B
10 4eis:A 225 232 0.3728 0.3778 0.3664 4.90e-35 4eis:B
11 4d7u:A 227 202 0.3553 0.3568 0.4010 1.48e-29 4d7u:B, 4d7v:A, 4d7v:B
12 4eir:A 223 196 0.2895 0.2960 0.3367 4.11e-21 4eir:B, 7t5c:A, 7t5c:B, 7t5d:A, 7t5d:B, 7t5e:A, 7t5e:B, 5tkf:A, 5tkf:C, 5tkf:B, 5tkf:D, 5tkg:A, 5tkg:B, 5tkh:A, 5tkh:B, 5tki:A, 5tki:B
13 5ufv:A 228 173 0.2500 0.2500 0.3295 1.90e-20 5ufv:B, 5ufv:C, 5ufv:D, 5ufv:E, 5ufv:F
14 5foh:A 218 199 0.3026 0.3165 0.3467 6.46e-20
15 8b7p:AAA 213 183 0.2982 0.3192 0.3716 8.10e-19 8b7p:BBB, 8b7p:CCC, 8b7p:DDD
16 5nlt:B 227 196 0.2675 0.2687 0.3112 8.19e-19 5nlt:A, 5nlt:C, 5nlt:D, 5nlt:E, 5nlt:F, 6ydc:A, 6ydc:B, 6ydc:C, 6ydc:D, 6ydd:A, 6ydd:B, 6yde:A, 6ydf:A, 6ydf:B
17 5acf:A 235 244 0.3289 0.3191 0.3074 1.79e-16 5acg:A, 5ach:A, 5aci:A, 5acj:A, 8e1w:A, 5n04:A, 5n05:A, 7nim:A, 7nin:A, 5nkw:A, 5nln:A, 5nlo:A, 5nlp:A, 5nlq:A, 5nlr:A, 5nls:A, 7pqr:A, 7ptz:AAA, 7pxi:A, 7pxj:A, 7pxk:A, 7pxl:A, 7pxm:A, 7pxn:A, 7pxr:A, 7pxs:A, 7pxt:A, 7pxu:A, 7pxv:A, 7pxw:A, 7pyd:A, 7pye:A, 7pyf:A, 7pyg:A, 7pyh:A, 7pyi:A, 7pyl:A, 7pym:A, 7pyn:A, 7pyo:A, 7pyp:A, 7pyq:A, 7pyu:A, 7pyw:A, 7pyx:A, 7pyy:A, 7pyz:A, 7pz0:A, 6ydg:A
18 6rs6:A 221 197 0.2851 0.2941 0.3299 9.33e-15 6rs9:A
19 3eii:A 208 87 0.1754 0.1923 0.4598 4.16e-13 3eii:B, 3eii:C, 3eii:D, 3eja:A, 3eja:B, 3eja:C, 3eja:D
20 4qi8:A 214 195 0.2807 0.2991 0.3282 5.96e-12 4qi8:B
21 4b5q:A 217 202 0.2632 0.2765 0.2970 2.40e-10 4b5q:B
22 7exk:A 217 92 0.1667 0.1751 0.4130 3.22e-10 7exk:B, 7exk:C, 7exk:D, 7exk:E, 7exk:F
23 7qbu:A 418 51 0.0658 0.0359 0.2941 1.4 7qbs:A, 7qbt:A, 7qbt:B, 7qbt:C, 7qbt:D, 7qbu:B, 7qbv:A, 7qbv:B, 7qbv:C, 7qbv:D
24 4f6o:A 268 62 0.0789 0.0672 0.2903 5.6 4f6p:A
25 1fc4:A 401 64 0.0789 0.0449 0.2812 7.5 1fc4:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218