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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HGEKSQQAFLRMRTLNWYDVKWSKTSLNVNESMVLSGKVHVFSAWPQAVANPKSSFLNAGEPGPVLVRTAQFIGEQFAPR
SVSLEVGKDYAFSIDLKARRAGRWHVHAQINVEGGGPIIGPGQWIEIKGDMADFKDPVTLLDGTTVDLETYGIDRIYAWH
FPWMIAAAAWILYWFFKKGIIASYLRISEGKDEEQIGDDDRRVGAIVLAVTILATIIGYAVTNSTFPRTIPLQAGLQKPL
TPIIVTAELKGGVYKVPGRELTIQVKVGEYTAAGLRFLNPDVFTTKDYLLADRGLSTDPTPLAPGETKTIEVKVQDARWD
IERLSDLAYDTDSQIGGLLMFFSPSGKRYATEIGGPVIPKFV

The query sequence (length=362) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3chx:A 362 362 1.0000 1.0000 1.0000 0.0 3chx:E, 3chx:I
2 4pi0:E 390 387 0.8646 0.8026 0.8088 0.0 4phz:A, 4phz:E, 4phz:I, 4pi0:A, 4pi0:I, 4pi2:E, 4pi2:A, 4pi2:I, 3rfr:A, 3rfr:E, 3rfr:I, 7s4m:A, 7s4m:E, 7s4m:I
3 7ev9:A 382 382 0.4834 0.4581 0.4581 2.11e-113 7ev9:E, 7ev9:I, 8oyi:A, 8oyi:E, 8oyi:I, 3rgb:A, 3rgb:E, 3rgb:I, 7s4h:A, 7s4h:E, 7s4h:I, 7s4i:A, 7s4i:E, 7s4i:I, 7s4j:A, 7s4j:E, 7s4j:I, 7s4k:A, 7s4k:E, 7s4k:I, 8sqw:A, 8sqw:E, 8sqw:I, 8sr1:A, 8sr1:E, 8sr1:I, 8sr2:A, 8sr2:E, 8sr2:I, 8sr4:A, 8sr4:E, 8sr4:I, 8sr5:A, 8sr5:E, 8sr5:I, 7t4o:A, 7t4o:E, 7t4o:I, 7t4p:A, 7t4p:E, 7t4p:I, 1yew:A, 1yew:E, 1yew:I
4 6cxh:A 382 382 0.4779 0.4529 0.4529 3.81e-112 7s4l:A, 7s4l:D, 7s4l:E
5 4o65:A 153 44 0.0414 0.0980 0.3409 0.004
6 2yc3:A 219 114 0.1050 0.1735 0.3333 1.9 5mrm:A, 5mro:A, 5mrp:A, 4nak:A, 4nal:A, 4nan:A, 1w77:A, 2yc5:A, 2ycm:A
7 6hrg:A 233 43 0.0442 0.0687 0.3721 2.4
8 5hqm:A 459 70 0.0497 0.0392 0.2571 4.3 5han:A, 5han:B, 5han:C, 5han:D, 5han:E, 5han:F, 5han:G, 5han:H, 5han:I, 5han:J, 5han:K, 5han:L, 5hao:A, 5hao:B, 5hao:C, 5hao:D, 5hao:E, 5hao:F, 5hat:A, 5hat:B, 5hat:C, 5hat:D, 5hat:E, 5hat:F, 5hat:G, 5hat:H, 5hat:I, 5hat:J, 5hat:K, 5hat:L, 5hjx:A, 5hjx:B, 5hjx:C, 5hjx:D, 5hjx:E, 5hjx:F, 5hjy:A, 5hjy:B, 5hjy:C, 5hjy:D, 5hjy:E, 5hjy:F, 5hk4:A, 5hk4:B, 5hk4:C, 5hk4:D, 5hk4:E, 5hk4:F, 5hql:A, 5hql:B, 5hql:C, 5hql:D, 5hql:E, 5hql:F, 5hqm:B, 5koz:A, 5koz:B, 5koz:C, 5koz:D, 5koz:E, 5koz:F, 5koz:G, 5koz:H, 5koz:I, 5koz:J, 5koz:K, 5koz:L, 4lf1:A, 4lf1:B, 4lf1:C, 4lf1:D, 4lf1:E, 4lf1:F, 4lf2:A, 4lf2:C, 4lf2:D
9 1t3q:B 786 73 0.0580 0.0267 0.2877 5.5 1t3q:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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