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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HGEKSQAAFMRMRTIHWFDLNWSKDQVSVNETMSISGKFHVFAGWPETVDKPEVAFLNIGIPGPVFIRAGSWIGGQLVPR
SVSLELGETYEFKVLLKARRPGDWHVHTMMNVQGGGPIIGPGKWVTITGSMGDFKNPITTLTGETIDLETYALDGVYGWH
LFWYLLGVAWMVYWCRKPVFIPRRIAVDAGKADSLITPTDKKVGMAFAAGTLAIVAVSMGQANEKYPVTTPLQAGLMRGI
KSLELPQPTVSVKVVDASYRVPGRAMQMTLEITNNGDSAVRLAEFNTASVRFLDADVYEDDTNYPDDLLAEEGLSVSDNS
PLAPGETRTVDVTASDAAWEVYRLADLIYDPDSRFAGLLFFIDEDGNRQMTMVDAPLIPTFI

The query sequence (length=382) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6cxh:A 382 382 1.0000 1.0000 1.0000 0.0 7s4l:A, 7s4l:D, 7s4l:E
2 7ev9:A 382 382 0.7304 0.7304 0.7304 0.0 7ev9:E, 7ev9:I, 8oyi:A, 8oyi:E, 8oyi:I, 3rgb:A, 3rgb:E, 3rgb:I, 7s4h:A, 7s4h:E, 7s4h:I, 7s4i:A, 7s4i:E, 7s4i:I, 7s4j:A, 7s4j:E, 7s4j:I, 7s4k:A, 7s4k:E, 7s4k:I, 8sqw:A, 8sqw:E, 8sqw:I, 8sr1:A, 8sr1:E, 8sr1:I, 8sr2:A, 8sr2:E, 8sr2:I, 8sr4:A, 8sr4:E, 8sr4:I, 8sr5:A, 8sr5:E, 8sr5:I, 7t4o:A, 7t4o:E, 7t4o:I, 7t4p:A, 7t4p:E, 7t4p:I, 1yew:A, 1yew:E, 1yew:I
3 4pi0:E 390 388 0.4660 0.4564 0.4588 3.60e-120 4phz:A, 4phz:E, 4phz:I, 4pi0:A, 4pi0:I, 4pi2:E, 4pi2:A, 4pi2:I, 3rfr:A, 3rfr:E, 3rfr:I, 7s4m:A, 7s4m:E, 7s4m:I
4 3chx:A 362 382 0.4529 0.4779 0.4529 6.28e-112 3chx:E, 3chx:I
5 4o65:A 153 38 0.0393 0.0980 0.3947 5.57e-04
6 6r4n:C 147 144 0.0942 0.2449 0.2500 0.016 6r4n:A, 6r4n:E
7 1zbu:B 304 74 0.0550 0.0691 0.2838 1.2 4l8r:B, 4l8r:E, 4qoz:B, 4qoz:E, 1w0h:A, 1zbh:A, 1zbh:D, 1zbh:B, 1zbh:C, 1zbu:A, 1zbu:C, 1zbu:D
8 5kdv:A 891 76 0.0681 0.0292 0.3421 1.4 7jtv:B, 7jtv:A, 5kdw:A, 5kdw:B, 5kdx:A, 5kdx:B
9 3jze:A 344 13 0.0262 0.0291 0.7692 6.5 3jze:B, 3jze:C, 3jze:D
10 6cz7:A 814 70 0.0550 0.0258 0.3000 8.5 6cz7:C, 6cz8:C, 6cz8:A, 6cz9:A, 6cz9:C, 6cza:A, 6cza:C
11 6a0t:B 332 58 0.0497 0.0572 0.3276 8.6 6a0s:B, 6a0s:A, 6a0t:A, 6a0u:B, 6a0u:A, 2ejw:A, 2ejw:B, 2ejw:E, 2ejw:F, 5xdf:A, 5xdf:B
12 1gp6:A 349 37 0.0288 0.0315 0.2973 9.0 2brt:A, 1gp4:A, 1gp5:A
13 6cty:C 353 12 0.0236 0.0255 0.7500 9.1 6cty:A, 6cty:B, 6cty:D, 6cty:E, 6cty:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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