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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HFRKHWQRRVRCHFDQPGKKVTRRLARRAKAAALAPRPVDKLRPIVRCPTVKYNRRTRLGRGFTLEELKAAGIPRLLAPT
IGIAVDHRRKNLSEESLAANVQRLKDYKARLILFPRK

The query sequence (length=117) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7olc:LL 209 117 1.0000 0.5598 1.0000 4.95e-82 8i9p:LL, 8i9r:LL, 8i9t:LL, 8i9v:LL, 8i9w:LL, 8i9x:LL, 8i9y:LL, 8i9z:LL, 8ia0:LL, 7old:LL, 8oo0:LL, 8pv1:LL, 8pv2:LL, 8pv3:LL, 8pv4:LL, 8pv5:LL, 8pv6:LL, 8pv7:LL, 8pv8:LL, 8pvk:LL, 8pvl:LL, 7z3n:LL, 7z3o:LL
2 7r81:N1 213 117 0.8376 0.4601 0.8376 3.75e-62
3 5it7:LL 197 117 0.6667 0.3959 0.6667 4.18e-54 6uz7:AL
4 8c3a:t 200 117 0.6496 0.3800 0.6496 2.93e-52 8c3a:BG, 8cq7:t, 8cq7:BG, 8cqw:t, 8cqw:BG, 8cre:t, 8cre:BG, 8oeq:t, 8oeq:BG, 7pzy:t, 7q08:t, 7q0f:t, 7q0p:t, 7q0r:t, 8q5i:t
5 4v7e:CL 208 118 0.6496 0.3654 0.6441 3.16e-50 8ip8:KB, 8ipa:KB, 8ipb:KB, 8jiv:CL
6 8hfr:LL 198 116 0.6581 0.3889 0.6638 6.69e-49 8aaf:t, 8agt:t, 8agu:t, 8agv:t, 8agw:t, 8agx:t, 8agz:t, 5apn:L, 5apo:L, 7azy:k, 7b7d:LN, 8bip:LL, 8bjq:LL, 8bn3:M3, 8bqd:AJ, 8bqx:AJ, 7bt6:L, 7btb:L, 6c0f:L, 6cb1:L, 8ccs:OO, 8cdl:OO, 8cdr:OO, 8ceh:OO, 8cf5:OO, 8cg8:OO, 8cgn:OO, 8civ:OO, 8cku:OO, 8cmj:OO, 5dat:M3, 5dat:m3, 5dc3:M3, 5dc3:m3, 5dge:M3, 5dge:m3, 5dgf:M3, 5dgf:m3, 5dgv:M3, 5dgv:m3, 8e5t:L, 6elz:L, 6em1:L, 6em3:L, 6em4:L, 6em5:L, 8eub:AL, 8evp:AL, 8evq:AL, 8evr:AL, 8evs:AL, 8evt:AL, 8ewb:AL, 8ewc:AL, 5fci:M3, 5fci:m3, 5fcj:M3, 5fcj:m3, 6ft6:L, 5gak:N, 6gq1:L, 6gqb:L, 6gqv:L, 5h4p:L, 6hd7:N, 6hhq:t, 6hhq:CN, 5i4l:M3, 5i4l:m3, 6i7o:AJ, 6i7o:XJ, 3j6x:53, 3j6y:53, 3j77:63, 3j78:63, 3jct:L, 5jcs:L, 5juo:Q, 5jup:Q, 5jus:Q, 5jut:Q, 5juu:Q, 8k2d:LL, 8k82:LL, 5lyb:M3, 5lyb:m3, 5m1j:L5, 6m62:L, 5mc6:AJ, 5mei:t, 5mei:CN, 7mpi:AL, 7mpj:AL, 6n8j:L, 6n8k:L, 6n8l:L, 6n8m:N, 6n8n:N, 6n8o:N, 7n8b:AL, 7nac:L, 5ndg:M3, 5ndg:m3, 5ndv:M3, 5ndv:m3, 5ndw:M3, 5ndw:m3, 7nrc:LN, 7nrd:LN, 5obm:M3, 5obm:m3, 7of1:L, 7oh3:L, 7ohp:L, 7ohq:L, 7ohr:L, 7ohs:L, 7ohu:L, 7ohv:L, 7ohw:L, 7ohx:L, 7ohy:L, 6oig:L, 5on6:t, 5on6:CN, 7osa:eL13, 7osm:eL13, 8p8m:JT, 8p8n:JT, 8p8u:JT, 8pfr:JT, 6q8y:AJ, 6qik:K, 6qt0:K, 6qtz:K, 7r7a:L, 6r84:N, 6r86:N, 6r87:N, 6ri5:K, 7rr5:LL, 6rzz:K, 6s05:K, 6s47:AN, 6snt:r, 6sv4:AJ, 6sv4:XJ, 6sv4:zJ, 6t4q:LL, 5t62:N, 5t6r:N, 6t7i:LL, 6t7t:LL, 6t83:Ly, 6t83:Na, 5tbw:t, 5tbw:CN, 6tb3:AJ, 5tga:M3, 5tga:m3, 5tgm:M3, 5tgm:m3, 6tnu:AJ, 7too:AL13, 7top:AL13, 7u0h:L, 4u3m:M3, 4u3m:m3, 4u3n:M3, 4u3n:m3, 4u3u:M3, 4u3u:m3, 4u4n:M3, 4u4n:m3, 4u4o:M3, 4u4o:m3, 4u4q:M3, 4u4q:m3, 4u4r:M3, 4u4r:m3, 4u4u:M3, 4u4u:m3, 4u4y:M3, 4u4y:m3, 4u4z:M3, 4u4z:m3, 4u50:M3, 4u50:m3, 4u51:M3, 4u51:m3, 4u52:M3, 4u52:m3, 4u53:M3, 4u53:m3, 4u55:M3, 4u55:m3, 4u56:M3, 4u56:m3, 4u6f:M3, 4u6f:m3, 7ug6:L, 7uoo:L, 7uqb:L, 7uqz:L, 7v08:L, 4v7f:K, 4v88:BL, 4v88:DL, 4v8t:L, 4v8y:BL, 4v8z:BL, 8v83:L, 8v84:L, 8v87:L, 4v91:L, 6woo:L, 6xiq:L, 6xir:L, 8y0u:LL, 6ylg:L, 6ylh:L, 6ylx:L, 6yly:L, 5z3g:P, 7z34:L, 6z6j:LL, 6z6k:LL, 7zpq:BK, 7zrs:BK, 7zs5:BM, 7zuw:BK, 7zux:EK, 7zw0:LO
7 8eug:L 202 117 0.6325 0.3663 0.6325 2.67e-48 8esq:L, 8esr:L, 8etc:L, 8etg:L, 8eth:L, 8eti:L, 8etj:L, 8eui:L, 8eup:L, 8euy:L, 8ev3:L
8 9bh5:CL 204 118 0.6239 0.3578 0.6186 6.24e-46 9cai:CL
9 7qiw:N 204 118 0.6496 0.3725 0.6441 1.67e-44 8azw:D, 8b2l:D3, 7qiz:N
10 7oya:L1 197 118 0.6496 0.3858 0.6441 3.57e-44 7oyb:L1
11 4v6w:CL 210 116 0.5812 0.3238 0.5862 2.01e-40 6xu6:CL, 6xu7:CL, 6xu8:CL
12 7oyc:L1 199 118 0.6068 0.3568 0.6017 6.57e-40
13 4v8p:AU 203 116 0.5556 0.3202 0.5603 1.44e-39 4v8p:DU, 4v8p:FU, 4v8p:HU
14 5xxb:K 199 116 0.5726 0.3367 0.5776 8.10e-39
15 5t5h:N 172 121 0.5641 0.3837 0.5455 8.80e-35
16 7a01:a7 210 118 0.6154 0.3429 0.6102 1.66e-34 8a3d:r, 5aj0:AL, 8b5l:L, 8b6c:L, 9bdl:AL13, 9bdn:AL13, 9bdp:AL13, 7bhp:LL, 8bhf:t3, 8bpo:K2, 8btk:BL, 7cpu:LL, 7cpv:LL, 4d5y:L, 4d67:L, 6d90:L, 6d9j:L, 9f1b:BL, 9f1c:BL, 9f1d:BL, 7f5s:LL, 8fkp:L6, 8fkq:L6, 8fkr:L6, 8fks:L6, 8fkt:L6, 8fku:L6, 8fkv:L6, 8fkw:L6, 8fkx:L6, 8fky:L6, 8fkz:L6, 8fl2:L6, 8fl3:L6, 8fl4:L6, 8fl6:L6, 8fl7:L6, 8fl9:L6, 8fla:L6, 8flb:L6, 8flc:L6, 8fld:L6, 8fle:L6, 8flf:L6, 6frk:L, 6ftg:L, 6fti:L, 6ftj:L, 8g5y:LL, 8g5z:LL, 8g60:LL, 8g61:LL, 8g6j:LL, 8glp:LL, 6gz3:AL, 6gz4:AL, 6gz5:AL, 6hcf:L3, 6hcj:L3, 6hcm:L3, 6hcq:L3, 8idt:Q, 8idy:Q, 8ie3:Q, 8ifd:2F, 8ife:2F, 8ine:Q, 8inf:Q, 8ink:Q, 6ip5:2F, 6ip6:2F, 6ip8:2F, 8ipd:Q, 8ipx:Q, 8ipy:Q, 8ir1:Q, 8ir3:Q, 3j7o:L, 3j7p:L, 3j7q:L, 3j7r:L, 3j92:L, 3jag:L, 3jah:L, 3jai:L, 3jaj:L, 3jan:L, 8jdj:Q, 8jdk:Q, 8jdl:Q, 8jdm:Q, 8k2c:LL, 5lks:LL, 6lqm:Q, 6lsr:Q, 6lss:Q, 7ls1:F1, 7ls2:F1, 6lu8:Q, 5lzs:L, 5lzt:L, 5lzu:L, 5lzv:L, 5lzw:L, 5lzx:L, 5lzy:L, 5lzz:L, 7mdz:L, 6mtb:L, 6mtc:L, 6mtd:L, 6mte:L, 7nfx:L, 7nwg:L3, 7nwh:L, 7nwi:L, 7o7y:BL, 7o7z:BL, 7o80:BL, 7o81:BL, 7obr:L, 8ohd:LL, 8oj0:LL, 8oj5:LL, 8oj8:LL, 6ole:M, 6olf:M, 6olg:AL, 6oli:M, 6olz:AL, 6om0:M, 6om7:M, 7ow7:r, 7oyd:L, 8p2k:BL, 6p5i:AL, 6p5j:AL, 6p5k:AL, 6p5n:AL, 8q7z:BL, 8q87:BL, 8qfd:L, 7qgg:M, 8qoi:LL, 7qvp:ML, 7qvp:LL, 7qwq:L, 7qwr:L, 7qws:L, 6qzp:LL, 6r5q:L, 6r6g:L, 6r6p:L, 6r7q:L, 8rjb:L, 8rjc:L, 8rjd:L, 8scb:L, 6sgc:L2, 6swa:K, 5t2c:r, 6t59:L3, 7tm3:L, 7toq:AL13, 7tor:AL13, 7tut:L, 7ucj:L, 7uck:L, 4ug0:LL, 4ujc:BL, 4ujd:AL, 4uje:CL, 4v6x:CL, 6w6l:M, 6xa1:LL, 7xnx:LL, 7xny:LL, 8xsx:LL, 8xsy:LL, 8xsz:LL, 6y0g:LL, 8y0w:LL, 8y0x:LL, 6y2l:LL, 6y57:LL, 6y6x:LL, 8yoo:LL, 8yop:LL, 6z6l:LL, 6z6m:LL, 6z6n:LL, 7zjw:LO, 7zjx:LO, 6zm7:LL, 6zme:LL, 6zmi:LL, 6zmo:LL, 6zvk:a7
17 8ova:BN 215 121 0.5726 0.3116 0.5537 5.52e-34 8ove:BN, 4v8m:BN
18 6zj3:LX 219 125 0.5726 0.3059 0.5360 2.49e-33
19 6zu5:LL0 164 114 0.4957 0.3537 0.5088 3.01e-33
20 5t2a:L 179 121 0.5299 0.3464 0.5124 1.22e-32 8a3w:I
21 8rxh:LI 214 121 0.5299 0.2897 0.5124 2.39e-32 8a98:I, 6az3:I, 3jcs:I, 8ovj:I, 8rxx:LI
22 3j79:L 211 117 0.5470 0.3033 0.5470 3.61e-32 3jbn:AL, 3jbo:AL, 3jbp:AL, 8tpu:AL, 5umd:L
23 6rm3:LL0 162 107 0.4444 0.3210 0.4860 6.08e-30
24 5xy3:L 185 113 0.5299 0.3351 0.5487 1.03e-29
25 8p5d:LL0 164 114 0.4444 0.3171 0.4561 1.78e-29 8p60:LL0, 8p60:KL0, 7qca:LL0
26 7qep:M3 161 114 0.4444 0.3230 0.4561 2.24e-26
27 8fru:L 202 109 0.4530 0.2624 0.4862 2.33e-26 8br8:LM, 8brm:LM, 8bsi:LM, 8bsj:LM, 8btd:LM, 8btr:LM, 7pwg:L, 7pwo:L2
28 8eyt:W 254 74 0.2051 0.0945 0.3243 0.17 4adv:V, 7afo:Y, 7o5h:V
29 2yqu:A 455 27 0.1111 0.0286 0.4815 1.9 2eq7:A, 2eq7:B, 2yqu:B
30 3maz:A 99 88 0.1709 0.2020 0.2273 2.0
31 6kbn:C 504 59 0.1453 0.0337 0.2881 2.7 6kbm:A, 6kbn:A
32 3l77:A 235 28 0.1111 0.0553 0.4643 3.9 3tn7:A, 3tn7:B
33 6geq:A 395 50 0.1453 0.0430 0.3400 4.5 3cxv:A, 3cxx:A, 3cxy:A, 3cxz:A, 3cy0:A, 3cy1:A, 5edt:A, 4g1x:A, 4g2g:A, 4g44:A, 4g45:A, 4g46:A, 4g47:A, 4g48:A, 3g5f:A, 3g5h:A, 6geo:A, 5ibd:A, 5ibe:A, 5ibf:A, 5ibg:A, 5ibh:A, 5ibi:A, 5ibj:A, 4ict:A, 2ij5:A, 2ij5:B, 2ij5:C, 2ij5:D, 2ij5:E, 2ij5:F, 2ij7:A, 2ij7:B, 2ij7:C, 2ij7:D, 2ij7:E, 2ij7:F, 4ips:A, 4ipw:A, 4iq7:A, 4iq9:A, 4ktf:A, 4ktj:A, 4ktk:A, 4ktl:A, 1n40:A, 1n4g:A, 7nqm:A, 7nqn:A, 7nqo:A, 5o4k:A, 5o4l:A, 5op9:A, 5opa:A, 6rq0:A, 6rq1:A, 6rq3:A, 6rq5:A, 6rq6:A, 6rq8:A, 6rq9:A, 6rqb:A, 6rqd:A, 6rqe:A, 7ruk:A, 7s0o:A, 8tdp:A, 8tdq:A, 6te7:A, 6tet:A, 6tev:A, 6upg:A, 6upi:A, 5wp2:A
34 7xde:A 562 28 0.1111 0.0231 0.4643 4.6 7bsj:A, 7bsj:B, 7bsk:A, 7bsk:B, 7bsl:A, 7bsl:B, 1do8:A, 1do8:D, 1do8:B, 1do8:C, 1efk:A, 1efk:D, 1efk:B, 1efk:C, 1efl:A, 1efl:B, 1efl:C, 1efl:D, 1gz3:A, 1gz3:B, 1gz3:C, 1gz3:D, 1gz4:A, 1gz4:B, 1gz4:C, 1gz4:D, 1pj2:A, 1pj2:D, 1pj2:B, 1pj2:C, 1pj3:A, 1pj3:B, 1pj3:C, 1pj3:D, 1pj4:A, 1pj4:B, 1pj4:C, 1pj4:D, 1pjl:A, 1pjl:B, 1pjl:C, 1pjl:D, 1pjl:E, 1pjl:F, 1pjl:G, 1pjl:H, 1qr6:A, 1qr6:B, 7xde:B, 7xde:C, 7xde:D, 7xdf:A, 7xdf:B, 7xdf:C, 7xdf:D, 7xdg:A, 7xdg:B, 7xdg:C, 7xdg:D
35 8ee6:A 1808 23 0.1026 0.0066 0.5217 7.2 8edw:A
36 7mtq:B 744 15 0.0684 0.0108 0.5333 8.4 8jd4:2
37 3s2u:A 331 29 0.1026 0.0363 0.4138 8.9
38 7epb:A 779 15 0.0684 0.0103 0.5333 9.0 7epb:B, 7mtq:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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