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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNY
FYPDNPKAYQISQFDQPIGENGYIDIEVDGETKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSPK
EAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFNYVRKGLEYEEKRQEEELLNGGEI
GQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTK
EMSDFFESTIEHGADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAAKGGNAK
QIMEDNGLVQ

The query sequence (length=410) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3ip4:B 482 410 1.0000 0.8506 1.0000 0.0 2df4:B, 2dqn:B, 2f2a:B, 2g5h:B, 2g5i:B
2 3h0l:B 410 408 0.5000 0.5000 0.5025 1.89e-153 3h0l:E, 3h0l:H, 3h0l:K, 3h0l:N, 3h0l:Q, 3h0l:T, 3h0l:W, 3h0m:B, 3h0m:E, 3h0m:H, 3h0m:K, 3h0m:N, 3h0m:Q, 3h0m:T, 3h0m:W, 3h0r:B, 3h0r:E, 3h0r:H, 3h0r:K, 3h0r:N, 3h0r:Q, 3h0r:T, 3h0r:W
3 4wj3:B 456 393 0.4756 0.4276 0.4962 4.76e-141 4wj3:K, 4wj3:H, 4wj3:E
4 3al0:B 482 417 0.4805 0.4087 0.4724 6.88e-135
5 3kfu:F 447 393 0.4488 0.4116 0.4682 6.18e-119 3kfu:I
6 2d6f:D 522 256 0.1561 0.1226 0.2500 3.13e-12 2d6f:C
7 2d6f:D 522 64 0.0488 0.0383 0.3125 0.029 2d6f:C
8 4nao:A 282 133 0.0780 0.1135 0.2406 1.3
9 4pi7:A 223 92 0.0634 0.1166 0.2826 1.9 4pi8:A, 4pi9:A
10 3n4k:A 163 104 0.0707 0.1779 0.2788 2.1
11 7e3q:B 159 133 0.0805 0.2075 0.2481 2.1
12 3gvp:A 433 41 0.0366 0.0346 0.3659 2.3 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
13 4jal:A 156 131 0.0878 0.2308 0.2748 2.4 4jal:B
14 8c2z:A 334 193 0.0780 0.0958 0.1658 2.7
15 7msw:A 635 152 0.0854 0.0551 0.2303 2.8 7exm:A, 7exm:B, 7exm:C, 7exm:D, 7msx:A
16 6bka:A 374 68 0.0439 0.0481 0.2647 4.7
17 4gpk:J 347 51 0.0341 0.0403 0.2745 6.0 4gpk:A, 4gpk:B, 4gpk:C, 4gpk:D, 4gpk:E, 4gpk:F, 4gpk:G, 4gpk:H, 4gpk:I, 4gpk:K, 4gpk:L
18 5vj0:D 300 85 0.0659 0.0900 0.3176 6.6 5gt2:A, 5gt2:B, 5gt2:C, 5gt2:D, 5vj0:A, 5vj0:B, 5vj0:C
19 5fgn:A 536 66 0.0488 0.0373 0.3030 9.2 4kav:A, 4kay:A, 4kay:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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