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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HFEKVEEILKKYGYKRENLIKILLEIQEIYRYLPEDVINYVSTAMGIPPAKIYGVATFYAQFSLKPKGKYTIMVCDGTAC
HMAGSPEVLKAIEEETGLTPGNVTEDLMFSLDQVGCLGACALAPVMVINGEVYGNLTADKVKEILRKIKEKERESA

The query sequence (length=156) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7p5h:C 156 156 1.0000 1.0000 1.0000 2.14e-113 7p5h:F, 7p5h:c, 7p5h:f, 7p8n:c, 7p8n:C, 7p91:c, 7p91:C, 7p92:C
2 8a6t:C 151 146 0.5064 0.5232 0.5411 1.82e-55 8a6t:F, 8bew:C, 8bew:F
3 7t2r:C 152 145 0.4359 0.4474 0.4690 2.85e-46 7t2r:H
4 8oh5:A 150 144 0.4551 0.4733 0.4931 7.32e-46 8oh5:D, 8oh5:G, 8oh5:J, 8oh9:A, 8oh9:D, 8oh9:G, 8oh9:J
5 8a5e:C 156 129 0.4038 0.4038 0.4884 2.19e-39 7q4v:C, 7q4v:G, 7q4w:C, 7q4w:G
6 8b9z:E 214 149 0.3654 0.2664 0.3826 6.27e-32 8ba0:E, 8esw:V2, 8esz:V2
7 5gup:E 197 151 0.3590 0.2843 0.3709 9.77e-32
8 7v2c:O 217 151 0.3590 0.2581 0.3709 4.64e-31 7ak5:E, 7ak6:E, 7b93:E, 8c2s:E, 8ca3:E, 8ca4:E, 8ca5:E, 7dgq:9, 7dgr:9, 7dgs:9, 7dgz:9, 7dh0:9, 7dkf:92, 6g2j:E, 6g72:E, 5gpn:d, 8iao:E, 8iap:E, 8ib4:E, 8ib5:E, 8ib9:E, 8iba:E, 8ibd:E, 8ibe:E, 8ic2:E, 8ic3:E, 5lc5:E, 5ldw:E, 5ldx:E, 5lnk:2, 5o31:E, 8olt:E, 8om1:E, 7psa:E, 8pw5:2, 8pw6:2, 8pw7:2, 8q0a:E, 8q0f:E, 8q0j:E, 8q0m:E, 8q0o:E, 8q0q:E, 8q1p:E, 8q1u:E, 8q1y:E, 8q25:E, 8q45:E, 8q46:E, 8q47:E, 8q48:E, 8q49:E, 8q4a:E, 6q9d:V2, 6qa9:V2, 6qbx:V2, 6qc2:V2, 6qc3:V2, 6qc4:V2, 6qc5:V2, 6qc6:V2, 6qc7:V2, 6qc8:V2, 6qc9:V2, 6qca:V2, 6qcf:V2, 7qsd:E, 7qsk:E, 7qsl:E, 7qsm:E, 7qsn:E, 7qso:E, 7r41:E, 7r42:E, 7r43:E, 7r44:E, 7r45:E, 7r46:E, 7r47:E, 7r48:E, 7r4c:E, 7r4d:E, 7r4f:E, 7r4g:E, 8rgp:2, 8rgq:2, 8rgr:2, 8rgt:2, 8ud1:1E, 8ueo:1E, 8uep:1E, 8ueq:1E, 8uer:1E, 8ues:1E, 8uet:1E, 8ueu:1E, 8uev:1E, 8uew:1E, 8uex:1E, 8uey:1E, 8uez:1E, 8ugh:1E, 8ugi:1E, 8ugj:1E, 8ugn:1E, 8ugn:5E, 8ugr:1E, 8ugr:5E, 7v2d:O, 7v2e:O, 7v2f:O, 7v2h:O, 7v2k:O, 7v2r:O, 7v30:O, 7v31:O, 7v32:O, 7v33:O, 7v3m:O, 7vb7:O, 7vbn:O, 7vbz:O, 7vwj:O, 7vxp:O, 7vxu:O, 7vy8:O, 7vya:O, 7vyf:O, 7vyh:O, 7vyn:O, 7vz1:O, 7vzv:O, 7vzw:O, 7w00:O, 7w0h:O, 7w0r:O, 7w0y:O, 7w1o:O, 7w1p:O, 7w1t:O, 7w1u:O, 7w1v:O, 7w1z:O, 7w20:O, 7w2k:O, 7w2l:O, 7w2r:O, 7w2u:O, 7w2y:O, 7w31:O, 7w32:O, 7w35:O, 7w4c:O, 7w4d:O, 7w4e:O, 7w4f:O, 7w4g:O, 7w4j:O, 7w4k:O, 7w4l:O, 7w4m:O, 7w4n:O, 7w4q:O, 5xtb:O, 5xtd:O, 5xth:O, 5xti:O, 5xti:BO, 7zd6:2, 7zdh:2, 7zdj:2, 7zdm:2, 7zdp:2, 7zeb:2, 6zk9:2, 6zkc:2, 6zkd:2, 6zke:2, 6zkf:2, 6zkg:2, 6zkh:2, 6zki:2, 6zkj:2, 6zkk:2, 6zkl:2, 6zkm:2, 6zkn:2, 6zko:2, 6zkp:2, 6zkq:2, 6zkr:2, 6zks:2, 6zkt:2, 6zku:2, 6zkv:2, 6zr2:E, 6ztq:E
9 7b0n:E 216 151 0.3333 0.2407 0.3444 2.40e-30 6gcs:H, 7o6y:H, 7o71:H, 6rfq:H, 6rfr:H, 6rfs:H, 6y79:H, 6yj4:E
10 7zmb:H 221 150 0.3397 0.2398 0.3533 3.45e-28 7zm7:H, 7zmg:H
11 9fdk:C 160 144 0.3269 0.3187 0.3542 2.94e-27 9fdj:A, 9fdj:C, 9fdk:A, 9fdv:A, 9fdv:C, 9fe0:A, 9fe0:C, 9fe5:A, 9fe5:C, 9fe7:A, 9fe7:C, 9fe8:A, 9fe8:C, 9fea:A, 9fea:C, 9fif:A, 9fif:C, 9fih:A, 9fih:C, 9fii:A, 9fii:C, 9fij:A, 9fij:C, 9fil:A, 9fil:C, 6hl2:A, 6hl2:C, 6hl3:A, 6hl3:C, 6hl4:A, 6hl4:C, 6hla:A, 6hla:C, 6hli:A, 6hli:C, 6hlj:A, 6hlj:C, 6hlm:A, 6hlm:C, 7q5y:E, 7q5y:K, 7q5y:Q, 7q5y:W, 6q9c:A, 6q9c:C, 6q9g:A, 6q9g:C, 6q9j:A, 6q9j:C, 6q9k:A, 6q9k:C, 8qg1:A, 8qg1:C, 8qgw:A, 8qgw:C, 8qh4:A, 8qh4:C, 8qh7:A, 8qh7:C, 8qhk:A, 8qhk:C, 6r7p:A, 6r7p:C, 6saq:A, 6saq:C
12 7awt:E 156 147 0.3013 0.3013 0.3197 1.21e-26 7nyr:E, 7nyu:E, 7nyv:E, 7nz1:E, 7p61:E, 7p62:E, 7p63:E, 7p64:E, 7p69:E, 7p7c:E, 7p7e:E, 7p7j:E, 7p7k:E, 7p7l:E, 7p7m:E, 7z7r:E, 7z7s:E, 7z7t:E, 7z7v:E, 7z80:E, 7z83:E, 7z84:E, 7zc5:E, 7zci:E
13 8b6f:AI 231 152 0.3269 0.2208 0.3355 8.62e-26 8bqs:AI, 8gym:v2, 8gym:V2, 8gzu:v2, 8gzu:V2, 7tgh:V2
14 8e9g:E 233 147 0.2949 0.1974 0.3129 1.11e-24 8e9h:E, 8e9i:E
15 3iam:2 179 152 0.3077 0.2682 0.3158 2.70e-24 2fug:2, 2fug:B, 2fug:K, 2fug:T, 4hea:2, 4hea:C, 6i0d:2, 6i0d:C, 6i1p:2, 6i1p:C, 3i9v:2, 3i9v:B, 3iam:B, 3ias:2, 3ias:B, 3ias:K, 3ias:T, 3m9s:2, 3m9s:B, 6q8o:2, 6q8o:C, 6q8w:2, 6q8w:C, 6q8x:2, 6q8x:C, 6y11:2, 6y11:C, 2ybb:2, 6ziy:2, 6zjl:2, 6zjn:2, 6zjy:2
16 8e73:V2 222 163 0.3590 0.2523 0.3436 1.58e-23 6x89:V2
17 7a23:B 219 163 0.3526 0.2511 0.3374 1.65e-23 7a24:B, 7aqr:E, 7ar7:E, 7ar8:E, 7arb:E, 8bed:E, 8bpx:E, 8bq5:E, 8bq6:E
18 6vw8:C 152 133 0.2436 0.2500 0.2857 5.85e-22 6vw7:A, 6vw7:C, 6vw8:A
19 2auv:A 85 80 0.2500 0.4588 0.4875 1.01e-21
20 6tg9:G 148 145 0.2756 0.2905 0.2966 1.51e-20 6tg9:C, 6tga:G, 6tga:C
21 7arc:E 235 166 0.3333 0.2213 0.3133 2.60e-20 7ard:E
22 8qby:E 236 155 0.2949 0.1949 0.2968 3.23e-20
23 8iuf:V2 225 131 0.2628 0.1822 0.3130 2.84e-15 8j9h:V2, 8j9i:V2, 8j9j:V2
24 7vw6:B 560 130 0.2372 0.0661 0.2846 1.62e-10 7e5z:B, 8j83:B, 7xqw:B
25 5xfa:A 581 111 0.2051 0.0551 0.2883 1.12e-09 5xf9:A, 5xf9:E, 5xfa:E
26 7p8n:B 613 79 0.1731 0.0440 0.3418 5.77e-04 7p5h:B, 7p5h:E, 7p5h:b, 7p5h:e, 7p8n:b, 7p91:b, 7p91:B, 7p92:B
27 7q4v:B 599 89 0.1603 0.0417 0.2809 0.001 8a5e:B, 7q4v:F, 7q4w:B, 7q4w:F
28 1f37:B 110 71 0.1410 0.2000 0.3099 0.001 1f37:A, 1m2a:A, 1m2a:B, 1m2b:A, 1m2b:B, 1m2d:A, 1m2d:B
29 7p8n:a 642 83 0.1603 0.0389 0.3012 0.003 7p5h:A, 7p5h:D, 7p5h:a, 7p5h:d, 7p8n:A, 7p91:a, 7p91:A, 7p92:A
30 8a6t:B 630 94 0.1923 0.0476 0.3191 0.009 8a6t:E, 8bew:B, 8bew:E
31 8swq:A 302 80 0.1538 0.0795 0.3000 1.2 5ifk:A, 5ifk:B, 5ifk:C, 8swp:A, 8swp:D, 8swp:E, 8swq:D, 8swr:A, 8swr:D, 8sws:A, 8sws:D, 8sws:E
32 7o7j:A 368 83 0.1603 0.0679 0.3012 1.4
33 2q5l:A 538 93 0.1410 0.0409 0.2366 2.4 2nxw:A, 2nxw:B, 2q5j:A, 2q5j:B, 2q5l:B, 2q5o:A, 2q5o:B, 2q5q:A, 2q5q:B
34 2ce7:D 413 40 0.0897 0.0339 0.3500 3.2 2ce7:A, 2ce7:B, 2ce7:E, 2ce7:F, 2cea:A, 2cea:B, 2cea:D, 2cea:E, 2cea:F
35 5e25:A 290 46 0.1026 0.0552 0.3478 3.2 5cm0:A, 5cm0:B, 5cm0:C, 5e25:B, 5e25:C
36 3kds:E 427 28 0.0705 0.0258 0.3929 3.4 2ce7:C, 2cea:C, 3kds:F, 3kds:G, 7tdo:A, 7tdo:B, 7tdo:C, 7tdo:D, 7tdo:E, 7tdo:F
37 8swq:B 278 73 0.1410 0.0791 0.3014 4.7 8swp:B, 8swq:E, 8swr:B, 8sws:B
38 7x7i:A 583 123 0.2179 0.0583 0.2764 5.5 7x7i:B, 7x7j:A, 7x7j:B, 7x7k:A, 7x7k:B
39 4s2r:P 615 68 0.1346 0.0341 0.3088 6.0 4s2r:Q, 4s2t:P, 4s2t:Q
40 4okm:A 346 30 0.0705 0.0318 0.3667 6.5 4okm:B, 4okm:C, 4okz:A, 4okz:B, 4okz:C, 4okz:D
41 5a4e:B 323 33 0.0833 0.0402 0.3939 6.9 6eif:C
42 8bv5:A 437 135 0.1923 0.0686 0.2222 7.5
43 5nqz:A 267 41 0.0833 0.0487 0.3171 7.9 5nqz:B
44 8q6o:F 275 24 0.0769 0.0436 0.5000 8.4 8q6o:7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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