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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
HDDLMLALALADRADELTRVRFGALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPDGVLGETTFTGRQWIVDPIDGT
KNFVRGVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRGAFASVDARPHRLSVSSVAELHSASLSFSSLSGWAGLR
ERFIGLTDTVWRVRAYGDFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVAGPHGGSAVATNGLLHD
EVLTRLN

The query sequence (length=247) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5zon:A 256 256 1.0000 0.9648 0.9648 7.72e-167 5yht:A, 5yht:B, 5zon:B, 5zon:C, 5zon:D
2 2p3n:A 256 247 0.3198 0.3086 0.3198 2.76e-25 2p3n:B, 2p3n:C, 2p3n:D
3 5eq9:B 260 199 0.2672 0.2538 0.3317 5.86e-24 5eq8:A, 5eq9:A, 5eq9:C, 5eq9:D, 5t3j:A
4 8wdq:A 273 238 0.3158 0.2857 0.3277 9.40e-18 8wdq:B
5 4as5:A 274 240 0.2915 0.2628 0.3000 5.43e-17 4as5:B, 4as5:C, 4as5:D
6 2bji:A 274 242 0.2955 0.2664 0.3017 1.15e-16 2bji:B
7 3lv0:A 258 207 0.2551 0.2442 0.3043 5.09e-16 3luz:A, 3lv0:B
8 3luz:B 234 190 0.2510 0.2650 0.3263 6.77e-15
9 6ib8:B 270 199 0.2429 0.2222 0.3015 2.51e-14 6ib7:A, 6ib8:A, 2qfl:A, 6tqn:T, 6tqn:S, 6tqo:T, 6tqo:S
10 2czi:A 259 234 0.2915 0.2780 0.3077 3.23e-14 2czh:B
11 1dk4:A 252 157 0.1741 0.1706 0.2739 7.40e-14 1dk4:B, 1g0h:A, 1g0h:B, 1g0i:A, 1g0i:B
12 6giu:A 275 242 0.2794 0.2509 0.2851 1.05e-13 4as4:A, 4as4:B, 1awb:A, 1awb:B, 6giu:B, 6gj0:A, 6gj0:B, 2hhm:A, 2hhm:B, 1ima:A, 1ima:B, 1imb:A, 1imb:B, 1imc:A, 1imc:B, 1imd:A, 1imd:B, 1ime:A, 1ime:B, 6zk0:AAA, 6zk0:BBB
13 5dw8:A 260 225 0.2713 0.2577 0.2978 1.08e-12 5dw8:B, 5j16:A, 5j16:B, 5j16:C, 5j16:D
14 4hxv:A 317 203 0.2267 0.1767 0.2759 2.83e-12 4o7i:A
15 5eyg:B 265 202 0.2105 0.1962 0.2574 1.27e-11 5eyg:A, 5eyh:A, 5eyh:B, 5f24:A, 5f24:B, 4g61:A, 4g61:B, 4i3e:A, 4i3e:B, 4i3y:A, 4i3y:B, 4i40:A, 4i40:B, 4ptk:A, 4ptk:B, 3ryd:A, 3ryd:C
16 1k9y:A 354 203 0.2389 0.1667 0.2906 7.70e-11 1k9z:A, 1ka0:A, 1ka1:A, 1qgx:A
17 6b5z:A 252 227 0.2591 0.2540 0.2819 4.23e-10 6b5z:B, 6b60:A, 6b60:B, 6b61:A, 6b61:B, 6b62:A, 6b62:B, 6b63:A, 6b63:B, 6b64:A, 6b64:B, 6b65:A, 6b65:B, 6b66:A, 6b66:B, 1lbx:A, 1lbx:B, 1lby:A, 1lby:B, 1lbz:A, 1lbz:B
18 8f9y:A 352 181 0.2065 0.1449 0.2818 2.54e-08
19 2wef:A 303 262 0.2429 0.1980 0.2290 1.60e-06 1jp4:A
20 5djj:A 257 64 0.1012 0.0973 0.3906 0.072 5djg:A, 5djh:A, 5dji:A, 5djk:A
21 1inp:A 400 184 0.1700 0.1050 0.2283 0.78
22 8wiv:D 602 103 0.1134 0.0465 0.2718 2.3 8wk0:D
23 8wiv:O 657 99 0.1093 0.0411 0.2727 2.4 8wiv:M, 8wiv:L, 8wj3:M, 8wj3:O, 8wj3:L, 8wk0:M, 8wk0:O, 8wk0:L
24 6dlh:A 704 110 0.1174 0.0412 0.2636 2.9 6dms:A, 6dns:A
25 1lml:A 465 27 0.0486 0.0258 0.4444 2.9
26 7kir:A 326 177 0.1538 0.1166 0.2147 3.7 7kio:A
27 1zh8:A 325 44 0.0607 0.0462 0.3409 7.4 1zh8:B
28 7bor:A 247 106 0.1255 0.1255 0.2925 7.9 7bor:C
29 3voc:A 416 66 0.0769 0.0457 0.2879 8.3
30 8f4r:B 1033 38 0.0810 0.0194 0.5263 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218