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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTG
LLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPP
VLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFL
GGQGAGPEEARRLGAEYMEDLKGLAEALWL

The query sequence (length=270) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5c8d:E 280 272 1.0000 0.9643 0.9926 0.0 8c31:A, 8c31:B, 8c31:C, 8c31:D, 8c32:A, 8c32:B, 8c32:C, 8c32:D, 8c33:A, 8c33:B, 8c33:C, 8c33:D, 8c34:A, 8c34:B, 8c34:C, 8c34:D, 8c35:A, 8c35:B, 8c35:C, 8c35:D, 8c36:A, 8c36:B, 8c36:C, 8c36:D, 8c37:A, 8c37:B, 8c37:C, 8c37:D, 8c73:A, 8c73:B, 8c73:C, 8c73:D, 8c76:A, 8c76:B, 8c76:C, 8c76:D, 5c8a:A, 5c8a:B, 5c8a:C, 5c8a:D, 5c8d:A, 5c8d:B, 5c8d:C, 5c8d:D, 5c8d:F, 5c8d:G, 5c8d:H, 5c8e:A, 5c8e:B, 5c8e:C, 5c8e:E, 5c8e:F, 5c8e:G, 5c8e:D, 5c8e:H, 5c8f:A, 3whp:A
2 7te2:A 205 71 0.1148 0.1512 0.4366 6.71e-10
3 8j2y:A 327 156 0.1852 0.1529 0.3205 1.19e-06 8j2y:B
4 5i44:B 68 51 0.0630 0.2500 0.3333 2.72e-04 5i44:A, 5i44:D, 5i44:E, 5i44:H, 5i44:J, 5i44:K, 5i44:G, 5i44:F, 5i44:I
5 8j2x:A 337 184 0.2185 0.1751 0.3207 4.17e-04 8j2w:A, 8j2w:B
6 4r24:B 85 71 0.1037 0.3294 0.3944 6.47e-04 4r22:B
7 7tec:A 72 58 0.0778 0.2917 0.3621 0.003
8 4jgi:B 206 147 0.1259 0.1650 0.2313 0.011 4jgi:A
9 7tea:B 78 59 0.0778 0.2692 0.3559 0.020 7tea:E, 7tea:A, 7tea:C
10 4r4e:B 84 76 0.1037 0.3333 0.3684 0.032
11 4z17:A 424 98 0.1222 0.0778 0.3367 0.089 4yws:A, 4z17:B, 4z1y:A, 4z1y:B
12 7xcn:P 215 212 0.1926 0.2419 0.2453 0.10 7xcn:M, 7xcn:N, 7xcn:O, 7xcn:Q, 7xcn:R
13 6jni:A 145 51 0.0630 0.1172 0.3333 0.46 6jgw:B, 6jgw:A, 6jgx:A, 6jgx:B, 6jni:B, 6jni:H, 6jni:C, 6jni:D, 6jni:E, 6jni:F, 6jni:G, 6jyw:A, 6jyw:B
14 3c9h:B 339 64 0.0704 0.0560 0.2969 1.3 3c9h:A
15 4ua1:B 125 57 0.0667 0.1440 0.3158 2.8 4ua1:A
16 7pwd:A 621 54 0.0519 0.0225 0.2593 3.4 6c2y:A, 3cik:A, 5he1:A, 7k7l:A, 3krw:A, 3krx:A, 3pvu:A, 3pvw:A, 5ukk:A, 5wg3:A, 5wg5:A
17 2fge:A 979 77 0.0889 0.0245 0.3117 4.1 2fge:B
18 8swu:A 269 35 0.0593 0.0595 0.4571 5.5 8swu:B, 8swu:C
19 8uau:A 332 95 0.1037 0.0843 0.2947 6.1
20 4xvi:A 647 122 0.1370 0.0572 0.3033 6.8 4xvk:A, 4xvl:A, 4xvm:A
21 5af7:B 391 131 0.1074 0.0742 0.2214 7.5 5af7:A, 5ahs:A, 5ahs:B, 5ahs:C, 5ahs:E, 5ahs:F, 5ahs:D
22 7acs:A 140 29 0.0481 0.0929 0.4483 8.4 7act:A, 8iv3:D, 8j6x:A, 8j6x:D, 6vyo:A, 6vyo:B, 6vyo:C, 6vyo:D, 6wkp:B, 6wkp:C, 6wkp:D, 7xwz:A, 7xwz:B, 7xx1:A, 7xx1:B, 7xx1:C, 7xx1:D
23 8ppg:B 243 41 0.0556 0.0617 0.3659 9.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218