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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGR
QRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKK

The query sequence (length=142) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5a2q:T 145 142 1.0000 0.9793 1.0000 5.09e-103 7a01:H5, 7a09:x, 5aj0:BT, 9bdl:AS19, 9bdn:AS19, 9bdp:AS19, 8bhf:U3, 9bkd:d, 9bln:d, 8btk:As, 7cpu:ST, 7cpv:ST, 4d5l:T, 4d61:T, 6d90:UU, 6d9j:UU, 9f1b:As, 9f1c:As, 9f1d:As, 6fec:R, 5flx:T, 6g18:T, 6g4s:T, 6g4w:T, 6g51:T, 6g53:T, 6g5h:T, 6g5i:T, 8g5y:ST, 8g5z:ST, 8g60:ST, 8g61:ST, 8g6j:ST, 8glp:ST, 6gz3:BT, 6gz4:BT, 6gz5:BT, 6hcf:U1, 6hcj:U2, 6hcm:U1, 6hcq:U2, 8ifd:20, 8ife:20, 6ip5:20, 6ip6:20, 6ip8:20, 3j7p:ST, 3j7r:ST, 3jag:TT, 3jah:TT, 3jai:TT, 3jaj:ST, 3jan:ST, 8jdj:AF, 8jdk:AF, 8jdl:AF, 8jdm:AF, 7jqb:U, 7jqc:U, 5k0y:R, 8k2c:ST, 7k5i:T, 4kzx:T, 4kzy:T, 4kzz:T, 5lks:ST, 7ls1:B3, 7ls2:B3, 5lzs:TT, 5lzt:TT, 5lzu:TT, 5lzv:TT, 5lzw:TT, 5lzx:TT, 5lzy:TT, 5lzz:TT, 7mdz:TT, 7mqa:NP, 6mtb:TT, 6mtc:TT, 6mtd:TT, 6mte:TT, 7nwg:U2, 7nwh:TT, 7nwi:TT, 7o7y:As, 7o7z:As, 7o80:As, 7o81:As, 5oa3:T, 6ole:ST, 6olf:ST, 6olg:BT, 6oli:ST, 6olz:BT, 6om0:ST, 6om7:ST, 7oyc:T2, 7oyd:TT, 8oz0:l, 8p03:V, 8p09:V, 8p2k:As, 6p4g:U, 6p4h:U, 6p5i:U, 6p5j:U, 6p5k:U, 6p5n:U, 8pj1:d, 8pj2:d, 8pj3:d, 8pj4:d, 8pj5:d, 8pj6:d, 8ppk:T, 8ppl:AT, 8q7z:As, 8q87:As, 7qgg:ST, 8qoi:ST, 7qp6:d, 7qp7:d, 7qvp:ST, 7qvp:RT, 6qzp:ST, 7r4x:T, 6r5q:PP, 6r6g:PP, 6r6p:PP, 6r7q:PP, 8scb:TT, 6sgc:U1, 7syg:U, 7syh:U, 7syi:U, 7syj:U, 7syk:U, 7syl:U, 7sym:U, 7syn:U, 7syo:U, 7syp:U, 7syq:U, 7syr:U, 7sys:U, 7syt:U, 7syu:U, 7syv:U, 7syw:U, 7syx:U, 5t2c:AU, 8t4s:T, 7toq:AS19, 7tor:AS19, 7tql:U, 7ucj:TT, 7uck:TT, 4ug0:ST, 4ujc:CT, 4ujd:CT, 4uje:BT, 4v6x:AT, 5vyc:T1, 5vyc:T2, 5vyc:T3, 5vyc:T4, 5vyc:T5, 5vyc:T6, 6w2s:U, 6w2t:U, 7wtt:T, 7wtu:T, 7wtv:T, 7wtw:T, 7wtx:T, 7wtz:T, 7wu0:T, 6xa1:ST, 7xnx:ST, 7xny:ST, 8xsx:ST, 8xsy:ST, 8xsz:ST, 8xxl:ST, 8xxm:ST, 8xxn:ST, 6y0g:ST, 8y0w:ST, 8y0x:ST, 6y2l:ST, 6y57:ST, 6yal:V, 6yam:V, 6yan:V, 6ybs:d, 8yoo:ST, 8yop:ST, 6z6l:ST, 6z6m:ST, 6z6n:ST, 7zjw:Se, 7zjx:Se, 6zlw:U, 6zm7:ST, 6zme:ST, 6zmi:ST, 6zmo:ST, 6zmt:U, 6zmw:d, 6zn5:U, 6zoj:T, 6zol:T, 6zon:x, 6zp4:x, 6zuo:T, 6zv6:T, 6zvh:T, 6zvj:x, 6zvk:H5, 6zxd:T, 6zxe:T, 6zxf:T, 6zxg:T, 6zxh:T
2 7oya:T2 137 137 0.8521 0.8832 0.8832 1.68e-87 7oyb:T2
3 4v6w:AT 154 136 0.6268 0.5779 0.6544 2.56e-62 6xu6:AT, 6xu7:AT, 6xu8:AT
4 7qiy:K 140 137 0.5563 0.5643 0.5766 9.27e-57 8auv:E, 8b2l:E1, 7qiz:UA
5 4v3p:SS 146 134 0.5493 0.5342 0.5821 2.19e-56 8ip8:ra, 8ip9:ra, 8ipa:ra, 8ipb:ra, 8jiw:BT, 8r57:T, 4v7e:BT
6 7olc:ST 142 141 0.5563 0.5563 0.5603 9.40e-51 7old:ST, 8oo0:ST, 6rxx:Cr, 7z3n:ST, 7z3o:ST
7 9bh5:AT 140 134 0.5352 0.5429 0.5672 1.85e-49 9cai:AT
8 7r81:U2 143 141 0.5493 0.5455 0.5532 4.76e-49
9 4v6i:AS 144 136 0.4930 0.4861 0.5147 2.30e-44 7a1g:J, 7aju:DT, 7b7d:I, 8bn3:C9, 8bqd:I, 8bqx:I, 8c00:I, 8c01:I, 8cah:J, 8cas:K, 8cbj:T, 8ccs:v, 8cdl:v, 8cdr:v, 8ceh:v, 8cf5:v, 8cg8:v, 8cgn:v, 8civ:v, 8cku:v, 8cmj:v, 7d4i:SU, 7d63:SU, 5dat:C9, 5dat:c9, 5dc3:C9, 5dc3:c9, 5dge:C9, 5dge:c9, 5dgf:C9, 5dgf:c9, 5dgv:C9, 5dgv:c9, 6eml:I, 8eub:BT, 8evp:BT, 8evq:BT, 8evr:BT, 8evs:BT, 8evt:BT, 8ewb:BT, 8ewc:BT, 6fai:T, 5fci:C9, 5fci:c9, 5fcj:C9, 5fcj:c9, 6gq1:AJ, 6gqb:AJ, 6gqv:AJ, 6hhq:U, 6hhq:c9, 5i4l:C9, 5i4l:c9, 6i7o:I, 6i7o:Ib, 3j6x:19, 3j6y:19, 3j77:19, 3j78:19, 5juo:QB, 5jup:QB, 5jus:QB, 5jut:QB, 5juu:QB, 8k2d:ST, 8k82:ST, 5lyb:C9, 5lyb:c9, 5m1j:T2, 5mc6:I, 5mei:c9, 5mei:U, 7mpi:BT, 7mpj:BT, 7n8b:BT, 5ndg:C9, 5ndg:c9, 5ndv:C9, 5ndv:c9, 5ndw:C9, 5ndw:c9, 7nrc:SI, 7nrd:SI, 5obm:C9, 5obm:c9, 5on6:c9, 5on6:U, 7osa:eS19, 7osm:eS19, 6q8y:I, 6rbd:T, 6rbe:T, 7rr5:ST, 6s47:BU, 6snt:T, 6sv4:I, 6sv4:Ib, 6sv4:Ic, 6t4q:ST, 6t7i:ST, 6t7t:ST, 6t83:Tb, 6t83:u, 5tbw:U, 5tbw:c9, 6tb3:I, 5tga:C9, 5tga:c9, 5tgm:C9, 5tgm:c9, 6tnu:I, 4u3m:C9, 4u3m:c9, 4u3n:C9, 4u3n:c9, 4u3u:C9, 4u3u:c9, 4u4n:C9, 4u4n:c9, 4u4o:C9, 4u4o:c9, 4u4q:C9, 4u4q:c9, 4u4r:C9, 4u4r:c9, 4u4u:C9, 4u4u:c9, 4u4y:C9, 4u4y:c9, 4u4z:C9, 4u4z:c9, 4u50:C9, 4u50:c9, 4u51:C9, 4u51:c9, 4u52:C9, 4u52:c9, 4u53:C9, 4u53:c9, 4u55:C9, 4u55:c9, 4u56:C9, 4u56:c9, 4u6f:C9, 4u6f:c9, 4uer:T, 4v7h:AT, 4v88:AT, 4v88:CT, 4v8y:AT, 4v8z:AT, 4v92:BT, 6wdr:T, 6woo:TT, 6xiq:AJ, 6xir:AJ, 8y0u:ST, 6y7c:T, 6z6j:ST, 6z6k:ST, 6zce:U, 7zpq:AT, 6zqd:DT, 6zqe:DT, 6zqf:DT, 6zqg:DT, 7zrs:AT, 6zu9:K, 7zuw:AT, 7zux:DT, 6zvi:B, 7zw0:sI
10 5xxu:T 151 136 0.4718 0.4437 0.4926 1.14e-42
11 6zj3:SX 143 134 0.4859 0.4825 0.5149 1.74e-42
12 6fyx:T 143 134 0.4859 0.4825 0.5149 4.03e-42 6fyy:T, 6gsm:T, 6gsn:T, 8i7j:T, 5it7:T, 5it9:T, 3j80:T, 3j81:T, 3jam:T, 3jap:T, 8rw1:T, 8s8d:T, 8s8e:T, 8s8f:T, 8s8g:T, 8s8h:T, 8s8i:T, 8s8j:T, 6uz7:T
13 8c3a:V 141 137 0.4577 0.4610 0.4745 6.93e-41 8c3a:DG, 8cq7:V, 8cq7:DG, 8cqw:V, 8cqw:DG, 8cre:V, 8cre:DG, 8oeq:V, 8oeq:DG, 7pzy:U, 7q08:U, 7q0f:U, 7q0p:U, 7q0r:U, 8q5i:U
14 5xyi:T 146 133 0.3732 0.3630 0.3985 2.38e-30
15 3j7a:Y 154 135 0.3592 0.3312 0.3778 1.46e-29 3jbn:Y, 3jbo:Y, 3jbp:Y, 6okk:Y, 8tpu:SY
16 6skf:Av 149 134 0.3803 0.3624 0.4030 3.70e-29 6skg:Av, 6th6:Av, 6tmf:V
17 6sw9:U 149 134 0.3803 0.3624 0.4030 2.81e-28 5jb3:U, 5jbh:U, 6swc:U, 6swe:U, 4v4n:BU, 4v6u:AU, 7zag:U, 7zah:U, 7zai:U, 7zhg:U
18 4v7r:AM 106 135 0.3944 0.5283 0.4148 9.81e-28 4v7r:CM
19 4bts:AT 154 140 0.3451 0.3182 0.3500 7.86e-27 4bts:BT, 4bts:CT, 4bts:DT, 4v5o:AT, 4v5o:BT
20 8ova:AO 154 137 0.3028 0.2792 0.3139 1.84e-23 8ove:AO, 4v8m:AO
21 6az1:X 152 136 0.3028 0.2829 0.3162 8.88e-22 8a3w:SX, 8a98:SX, 8ovj:SX, 8rxh:SX, 8rxx:SX, 5t2a:AO
22 7ase:O 140 132 0.2958 0.3000 0.3182 1.22e-21 5opt:o
23 8bsi:SW 138 133 0.3028 0.3116 0.3233 1.57e-20 8br8:SW, 8brm:SW, 8bsj:SW, 8btd:SW, 8btr:SW, 8fvy:T, 8g4s:T, 7pwf:T, 7pwo:T1
24 8hkx:S19E 150 137 0.3662 0.3467 0.3796 1.03e-19 8hky:S19E, 8hkz:S19E, 8hl1:S19E, 8hl2:S19E, 8hl3:S19E, 8hl4:S19E, 8hl5:S19E, 8wkp:S19E, 8wq2:S19E, 8wq4:S19E
25 6zu5:ST0 139 126 0.2887 0.2950 0.3254 8.38e-15
26 8p5d:ST0 142 117 0.2606 0.2606 0.3162 6.58e-12 8p60:ST0, 8p60:RT0, 7qca:ST0
27 7qep:C9 135 105 0.1972 0.2074 0.2667 2.65e-11
28 6rm3:ST0 131 102 0.1690 0.1832 0.2353 1.42e-07
29 7bgi:8 217 31 0.0915 0.0599 0.4194 0.082 7blx:8, 7d0j:8, 7dz7:8, 7dz8:8, 8h2u:8, 6ijj:8, 6ijo:8, 6jo5:8, 6jo6:8, 7r3k:8, 7wyi:8, 7wzn:8, 7zq9:8, 7zqc:8, 7zqd:8, 7zqd:82
30 8s0l:A 369 46 0.1056 0.0407 0.3261 1.0 8hd8:A, 8hd8:C, 8hd8:B, 8hd8:D, 7meq:A, 8v04:B, 8v1f:C, 8v1f:B, 8v1f:D, 7xyd:A, 7xyd:C, 7xyd:B, 7xyd:D, 7y0e:A, 7y0e:C, 7y0e:B, 7y0e:D, 7y0f:A, 7y0f:C, 7y0f:B, 7y0f:D
31 8p7e:A 309 50 0.1127 0.0518 0.3200 1.4 8p7e:B, 8p8f:A, 8p8f:B
32 4aze:A 350 70 0.1549 0.0629 0.3143 2.8 6a1f:A, 6a1g:A, 6a1g:B, 5a3x:A, 5a3x:B, 5a3x:C, 5a3x:D, 5a4e:A, 5a4e:C, 5a4e:D, 5a4l:A, 5a4l:B, 5a4l:C, 5a4l:D, 5a4q:A, 5a4q:B, 5a4q:C, 5a4q:D, 5a4t:A, 5a4t:B, 5a4t:C, 5a4t:D, 7a4o:A, 7a4o:B, 7a4r:A, 7a4r:B, 7a4w:A, 7a4w:B, 7a4z:A, 5a54:A, 5a54:B, 5a54:C, 5a54:D, 7a51:A, 7a52:A, 7a52:B, 7a53:A, 7a53:B, 7a55:A, 7a55:B, 7a5b:A, 7a5b:B, 7a5d:A, 7a5l:A, 7a5n:A, 7a5n:B, 5aik:A, 5aik:B, 5aik:C, 5aik:D, 7aj2:A, 7aj4:A, 7aj5:A, 7aj7:A, 7aj8:A, 7aja:A, 7ajm:A, 7ajm:B, 7ajs:A, 7ajs:B, 7ajv:A, 7ajv:B, 7ajw:A, 7ajy:A, 7ajy:B, 7ak2:A, 7ak2:B, 7aka:A, 7aka:B, 7akb:A, 7akb:B, 7ake:A, 7ake:B, 7akl:A, 3anq:A, 3anq:B, 3anq:C, 3anq:D, 3anr:A, 3anr:B, 3anr:C, 3anr:D, 4aze:B, 4aze:C, 8c3g:A, 8c3g:B, 8c3g:C, 8c3g:D, 8c3q:A, 8c3q:B, 8c3r:A, 8c3r:B, 6eif:A, 6eif:B, 6eif:D, 6eij:A, 6eij:B, 6eij:C, 6eij:D, 6eil:A, 6eil:B, 6eil:D, 6eip:A, 6eip:B, 6eip:C, 6eip:D, 6eiq:A, 6eiq:B, 6eiq:C, 6eiq:D, 6eir:A, 6eir:B, 6eir:C, 6eir:D, 6eis:A, 6eis:B, 6eis:C, 6eis:D, 6eiv:A, 6eiv:B, 6eiv:C, 6eiv:D, 6ej4:A, 6ej4:B, 6ej4:C, 6ej4:D, 7fhs:A, 7fhs:B, 7fhs:C, 7fhs:D, 7fht:A, 7fht:B, 7fht:C, 7fht:D, 6ln1:A, 6ln1:B, 4mq1:A, 4mq1:B, 4mq1:C, 4mq1:D, 4mq2:A, 4mq2:B, 4mq2:C, 4mq2:D, 4nct:A, 4nct:B, 4nct:C, 4nct:D, 7o7k:A, 7o7k:B, 7oy6:C, 6qu2:A, 6qu2:B, 6qu2:C, 6qu2:D, 8r8e:A, 8r8e:B, 8r8e:C, 8r8e:D, 6s11:A, 6s11:B, 6s14:A, 6s17:A, 6s1b:A, 6s1h:A, 6s1i:A, 6s1i:B, 6s1i:C, 6s1i:D, 6s1j:A, 8t2h:A, 8t2h:B, 6t6a:A, 6t6a:B, 6t6a:C, 6uip:A, 6uip:B, 6uwy:A, 6uwy:B, 6uwy:C, 6uwy:D, 2vx3:A, 2vx3:B, 2vx3:C, 2vx3:D, 2wo6:B, 2wo6:A, 6yf8:A, 6yf8:B, 6yf8:C, 6yf8:D, 4ylj:A, 4ylj:B, 4ylj:C, 4ylj:D, 4ylk:A, 4yll:A, 4yu2:A, 4yu2:B, 4yu2:C, 4yu2:D, 7z5n:A, 7z5n:B, 7z5n:C, 7z5n:D, 7z5n:E, 7z5n:F, 7z5n:G, 7zh8:A, 7zh8:B, 7zh8:C, 7zh8:D
33 7mop:A 2445 45 0.1056 0.0061 0.3333 3.4 6fyh:A, 6pfl:A, 6pfl:B, 8r7o:A, 8r7o:C, 8rd0:C, 8rd0:D, 8rd1:A, 8rd1:C, 8rd1:D, 8rd7:D, 6xz1:A
34 1oai:A 59 20 0.0704 0.1695 0.5000 4.5
35 5euh:A 164 39 0.0845 0.0732 0.3077 5.6 5euh:B
36 8rwk:A 495 34 0.0845 0.0242 0.3529 5.7 8rwk:B, 8rwk:C, 8rwk:D
37 7a7a:B 667 41 0.0845 0.0180 0.2927 9.4 7a2i:B, 7a7a:A, 7a7c:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218