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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GVSIRSMKNFYDWIKEFVRDQGEFIAQQSGWLELERSSYAKLIAQTISHVLNGGSLLVSADSSRHWFLNYILSNLNPKDL
KERPLLSVIDFNASSFYPKNDANLSLATIEMTYQNPMFWHVGKIENEGLKTILLSKIPSFLWLFEELKEDCLLLKEHDSL
LDYKLLQLFKLFENALFSVLYNKVTL

The query sequence (length=186) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2uvp:C 186 186 1.0000 1.0000 1.0000 8.13e-136 2uvp:B
2 7uny:C 127 78 0.0968 0.1417 0.2308 0.63 7uny:B
3 8om5:A 828 78 0.1022 0.0229 0.2436 0.96 8omo:A
4 8ag6:A 896 78 0.1022 0.0212 0.2436 1.1 2o8b:A, 2o8c:A, 2o8d:A, 2o8e:A, 2o8f:A, 8olx:A, 8om9:A, 8oma:A, 8omq:A, 3thw:A, 3thx:A, 3thy:A, 3thz:A
5 3rmp:A 77 19 0.0538 0.1299 0.5263 3.1 3rmp:C
6 9fp6:A 732 53 0.0699 0.0178 0.2453 4.4 9fp6:B, 9fp6:C, 9fp6:D, 9fp6:E, 9fp6:F
7 2es2:A 67 32 0.0645 0.1791 0.3750 4.9 3pf4:B, 3pf5:B, 3pf5:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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