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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GVKIRDLVKHRNERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLLMDKLCQTYDALTVNTECTVEIYGAIKEVPAPNG
HELIADFWKIIGNAPPGGIDNVLNEEASVDKMLDNRHLVIRGENAAALLRLRAAATRAMREHFYNAGYVEVAPPTLVQTQ
VSTLFNLDYFGEQSFLTQSSQLYLETCIPTLGDVFCIAQSYRAEKSRTRRHLAEYAHVEAECPFITLDDLMEKIEELVCD
TVDRLLADEEAKKLLEHINPKFQPPERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGEDIAEAAERFMTDTINKPILLNR
FPSEIKAFYMQRDAKDNTLTESVDLLMPGVGEIVGGSMRIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGTCPHGGYGLG
LERFICWLTNTNHIRDVCLYPRFVGRCVP

The query sequence (length=429) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xgt:B 433 433 0.9953 0.9861 0.9861 0.0 2xgt:A, 2xti:A, 2xti:B
2 8tc8:A 435 435 0.6434 0.6345 0.6345 0.0 8h53:A, 8h53:B, 8h53:C, 8h53:D, 8tc8:B, 8tc8:C, 8tc8:D, 8tc9:A, 8tc9:B, 8tc9:C, 8tc9:D
3 3m4p:A 435 436 0.4825 0.4759 0.4748 1.95e-144 3m4p:B, 3m4p:C, 3m4p:D
4 1x54:A 434 429 0.3753 0.3710 0.3753 2.00e-82 1x55:A
5 1b8a:A 438 432 0.2984 0.2922 0.2963 3.21e-52 1b8a:B, 3nel:A, 3nem:A, 3nem:B
6 1asy:A 490 471 0.2890 0.2531 0.2633 1.98e-32 1asy:B, 1asz:A, 1asz:B
7 3kfu:C 377 432 0.2751 0.3130 0.2731 1.45e-31 3kfu:A, 3kfu:D, 3kfu:B
8 7qh8:A 471 440 0.2611 0.2378 0.2545 9.38e-13 7qhn:A, 7qi8:A
9 3p8v:A 294 265 0.1585 0.2313 0.2566 2.54e-12 3p8v:B, 3p8y:A, 3p8y:B, 3reu:A, 3reu:B, 3rex:A, 3rex:B, 3rl6:A, 3rl6:B
10 5w25:A 583 248 0.1445 0.1063 0.2500 7.19e-12 5w25:B
11 5w25:A 583 97 0.0653 0.0480 0.2887 1.28e-05 5w25:B
12 4wj3:M 589 244 0.1445 0.1053 0.2541 1.13e-10 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
13 4wj3:M 589 89 0.0653 0.0475 0.3146 1.86e-07 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
14 1c0a:A 585 250 0.1538 0.1128 0.2640 7.83e-10 1il2:A, 1il2:B
15 1c0a:A 585 191 0.1212 0.0889 0.2723 2.41e-09 1il2:A, 1il2:B
16 4o2d:B 515 245 0.1469 0.1223 0.2571 1.47e-09
17 4o2d:B 515 97 0.0746 0.0621 0.3299 5.08e-08
18 4o2d:A 580 245 0.1469 0.1086 0.2571 1.80e-09 4rmf:A
19 4o2d:A 580 97 0.0746 0.0552 0.3299 5.83e-08 4rmf:A
20 3a74:A 484 329 0.1772 0.1570 0.2310 1.89e-09 3a74:B, 3a74:C, 3a74:D, 3e9h:A, 3e9h:B, 3e9h:C, 3e9h:D, 3e9i:A, 3e9i:B, 3e9i:C, 3e9i:D
21 6nrz:A 517 338 0.1748 0.1451 0.2219 4.16e-09 6nrz:B, 6ns0:A, 6ns0:B, 6o3f:A, 6o3f:B
22 1bbu:A 486 336 0.1678 0.1481 0.2143 2.96e-08
23 6sjc:B 581 300 0.1772 0.1308 0.2533 3.24e-08 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
24 6sjc:B 581 85 0.0629 0.0465 0.3176 5.51e-06 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
25 6wbd:B 485 343 0.1795 0.1588 0.2245 3.65e-08 6wbd:A
26 1e1t:A 485 322 0.1725 0.1526 0.2298 1.14e-07 1e1o:A, 1e22:A, 1e24:A, 1lyl:A, 1lyl:B, 1lyl:C, 5yzx:A, 5yzx:B, 5yzx:C
27 6aqg:C 490 451 0.2378 0.2082 0.2262 4.86e-07 6aqg:A, 6aqg:B, 6aqg:D, 5vl1:A, 5vl1:B, 5vl1:C, 5vl1:D
28 6bni:A 502 341 0.1865 0.1594 0.2346 7.23e-06 6bni:B, 6c86:A, 6c86:B, 5eln:A, 5eln:B, 5eln:C, 5eln:D, 5elo:A, 5elo:B, 5elo:C, 5elo:D, 6hcw:A, 6hcw:B, 7zog:A, 7zog:B, 7zog:C, 7zog:D
29 5zh2:A 464 253 0.1352 0.1250 0.2292 8.11e-06
30 4ex5:A 486 335 0.1795 0.1584 0.2299 5.59e-05 4ex5:B
31 6agt:B 506 33 0.0420 0.0356 0.5455 1.02e-04 6agt:A, 6agt:C, 6agt:D, 7bt5:A, 7bt5:B, 6hcu:A, 6hcu:B, 6hcv:A, 6hcv:B, 8k9s:A, 8k9s:B, 8k9u:A, 8k9u:B, 8k9v:A, 8k9v:B, 8k9w:A, 8k9w:B, 8k9x:A, 8k9x:B, 6ka6:A, 6ka6:B, 6ka6:C, 6ka6:D, 6kab:A, 6kab:B, 6kab:C, 6kab:D, 6kbf:A, 6kbf:B, 6kcn:A, 6kcn:B, 6kcn:C, 6kcn:D, 6kct:A, 6kct:B, 6kct:C, 6kct:D, 6l3y:B, 6l3y:A, 6l4q:B, 6l4q:A, 6m0t:A, 6m0t:B, 6m0t:C, 6m0t:D, 4pg3:A, 4pg3:B, 4pg3:C, 4pg3:D, 4ycv:A, 4ycv:B, 4ycv:C, 4ycv:D, 5zh2:B, 5zh3:A, 5zh3:B, 5zh4:A, 5zh4:B, 5zh5:A, 5zh5:B
32 6aqh:B 490 450 0.2308 0.2020 0.2200 2.21e-04 6aqh:A, 6aqh:C, 6aqh:D
33 7f6w:A 506 33 0.0373 0.0316 0.4848 0.001
34 7f6w:A 506 39 0.0396 0.0336 0.4359 3.3
35 6chd:A 506 33 0.0326 0.0277 0.4242 0.004 3bju:A, 3bju:B, 3bju:C, 3bju:D, 6chd:B, 4dpg:A, 4dpg:B, 4dpg:C, 4dpg:D, 4dpg:E, 4dpg:F, 4dpg:G, 4dpg:H, 7ea9:A, 7ea9:B, 7ea9:C, 7ea9:D, 6ild:A, 6ild:B, 6ilh:A, 6ilh:B, 4ycu:A, 4ycu:B, 4ycw:A, 4ycw:B, 4ycw:E, 4ycw:F
36 5hgq:B 482 316 0.1585 0.1411 0.2152 0.005 5hgq:A, 5hgq:D, 5hgq:C
37 4up7:A 529 39 0.0326 0.0265 0.3590 0.024 4up9:A, 4upa:A
38 5in4:A 355 64 0.0373 0.0451 0.2500 1.0 6gpj:A, 6gpj:B, 6gpj:D, 6gpj:C, 6gpk:A, 6gpk:B, 6gpk:C, 6gpk:D, 6gpl:B, 6gpl:E, 6gpl:C, 6gpl:D, 5in4:B, 5in4:C, 5in4:D, 5in5:A, 5in5:B, 5in5:C, 5in5:D, 6q94:B, 6q94:A, 6q94:C, 6q94:E, 6q94:D, 6q94:F, 6q94:G, 6q94:H, 1t2a:A, 1t2a:D, 1t2a:B, 1t2a:C
39 1jnw:A 214 61 0.0420 0.0841 0.2951 3.8 1dnl:A, 1g76:A, 1g77:A, 1g78:A, 1g79:A, 6ylz:AAA, 6ymh:BBB
40 6u6x:C 376 88 0.0513 0.0585 0.2500 5.2
41 2dq3:A 425 81 0.0606 0.0612 0.3210 7.2 2dq3:B
42 5yko:A 487 90 0.0513 0.0452 0.2444 8.7 5ykn:A
43 6ujd:A 406 95 0.0490 0.0517 0.2211 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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