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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAV
VVGTITDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHS
HTKPYVRSKGRKFERARGRRASRGYKN

The query sequence (length=187) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v6x:CQ 188 187 0.9679 0.9628 0.9679 3.31e-130 7a01:S2, 8a3d:K, 5aj0:AQ, 8b5l:Q, 8b6c:Q, 9bdl:AL18, 9bdn:AL18, 9bdp:AL18, 7bhp:LQ, 8bhf:D1, 8bpo:P2, 8btk:BQ, 7cpu:LQ, 7cpv:LQ, 4d5y:Q, 4d67:Q, 6d90:Q, 6d9j:Q, 9f1b:BQ, 9f1c:BQ, 9f1d:BQ, 7f5s:LQ, 8fkp:LB, 8fkq:LB, 8fkr:LB, 8fks:LB, 8fkt:LB, 8fku:LB, 8fkv:LB, 8fkw:LB, 8fkx:LB, 8fky:LB, 8fkz:LB, 8fl0:LB, 8fl2:LB, 8fl3:LB, 8fl4:LB, 8fl6:LB, 8fl7:LB, 8fl9:LB, 8fla:LB, 8flb:LB, 8flc:LB, 8fld:LB, 8fle:LB, 8flf:LB, 6frk:Q, 6ftg:Q, 6fti:Q, 6ftj:Q, 8g5y:LQ, 8g5z:LQ, 8g60:LQ, 8g61:LQ, 8g6j:LQ, 8glp:LQ, 6gz3:AQ, 6gz4:AQ, 6gz5:AQ, 6hcf:Q3, 6hcj:Q3, 6hcm:Q3, 6hcq:Q3, 8idt:Z, 8idy:Z, 8ie3:Z, 8ifd:2K, 8ife:2K, 8ine:Z, 8inf:Z, 8ink:Z, 6ip5:2K, 6ip6:2K, 6ip8:2K, 8ipd:Z, 8ipx:Z, 8ipy:Z, 8ir1:Z, 8ir3:Z, 3j7o:Q, 3j7p:Q, 3j7q:Q, 3j7r:Q, 3j92:Q, 3jag:Q, 3jah:Q, 3jai:Q, 3jaj:Q, 3jan:Q, 8jdj:V, 8jdk:V, 8jdl:V, 8jdm:V, 8k2c:LQ, 5lks:LQ, 6lqm:Z, 6lsr:Z, 6lss:Z, 7ls1:K2, 7ls2:K2, 6lu8:Z, 5lzs:Q, 5lzt:Q, 5lzu:Q, 5lzv:Q, 5lzw:Q, 5lzx:Q, 5lzy:Q, 5lzz:Q, 7mdz:Q, 6mtb:Q, 6mtc:Q, 6mtd:Q, 6mte:Q, 7nfx:Q, 7nwg:Q3, 7nwh:Q, 7nwi:Q, 7o7y:BQ, 7o7z:BQ, 7o80:BQ, 7o81:BQ, 7obr:Q, 8ohd:LQ, 8oj0:LQ, 8oj5:LQ, 8oj8:LQ, 6ole:R, 6olf:R, 6olg:AQ, 6oli:R, 6olz:AQ, 6om0:R, 6om7:R, 7ow7:K, 7oyd:Q, 8p2k:BQ, 6p5i:AQ, 6p5j:AQ, 6p5k:AQ, 6p5n:AQ, 8q7z:BQ, 8q87:BQ, 8qfd:Q, 7qgg:R, 8qoi:LQ, 7qvp:LQ, 7qvp:MQ, 7qwq:Q, 7qwr:Q, 7qws:Q, 6qzp:LQ, 6r5q:Q, 6r6g:Q, 6r6p:Q, 6r7q:Q, 8rjb:Q, 8rjc:Q, 8rjd:Q, 8scb:Q, 6sgc:Q2, 6swa:P, 5t2c:K, 6t59:Q3, 7tm3:Q, 7toq:AL18, 7tor:AL18, 7tut:Q, 7ucj:Q, 7uck:Q, 4ug0:LQ, 4ujc:BQ, 4ujd:AQ, 4uje:CQ, 4v5z:Bo, 6w6l:R, 6xa1:LQ, 7xnx:LQ, 7xny:LQ, 8xsx:LQ, 8xsy:LQ, 8xsz:LQ, 6y0g:LQ, 8y0w:LQ, 8y0x:LQ, 6y2l:LQ, 6y57:LQ, 6y6x:LQ, 8yoo:LQ, 8yop:LQ, 6z6l:LQ, 6z6m:LQ, 6z6n:LQ, 7zjw:LT, 7zjx:LT, 6zm7:LQ, 6zme:LQ, 6zmi:LQ, 6zmo:LQ, 6zvk:S2
2 7oya:Q1 180 180 0.8342 0.8667 0.8667 2.26e-114 7oyb:Q1
3 7oyc:Q1 180 180 0.8396 0.8722 0.8722 1.17e-113
4 4v6w:CQ 187 186 0.6952 0.6952 0.6989 1.55e-92 6xu6:CQ, 6xu7:CQ, 6xu8:CQ
5 8azw:G 186 187 0.6684 0.6720 0.6684 1.67e-86 8b2l:G3, 7qiw:S, 7qiz:S
6 8jiv:CQ 187 188 0.6578 0.6578 0.6543 1.06e-83 8ip8:JA, 8ipa:JA, 8ipb:JA, 4v3p:LR, 4v7e:CQ
7 9bh5:CQ 187 187 0.6524 0.6524 0.6524 6.15e-78 9cai:CQ
8 5xxb:P 186 188 0.6043 0.6075 0.6011 1.96e-71
9 7r81:S1 182 186 0.6043 0.6209 0.6075 3.52e-70
10 8eug:Q 186 188 0.5882 0.5914 0.5851 1.77e-67 8esq:Q, 8esr:Q, 8etc:Q, 8etg:Q, 8eth:Q, 8eti:Q, 8etj:Q, 8eui:Q, 8eup:Q, 8euy:Q, 8ev3:Q
11 3j79:S 186 173 0.5508 0.5538 0.5954 3.98e-66 3jbn:AS, 3jbo:AS, 3jbp:AS, 8tpu:AS, 5umd:S
12 7olc:LQ 183 174 0.5722 0.5847 0.6149 9.47e-65 8i9p:LQ, 8i9r:LQ, 8i9t:LQ, 8i9v:LQ, 8i9w:LQ, 8i9x:LQ, 8i9y:LQ, 8i9z:LQ, 8ia0:LQ, 7old:LQ, 8oo0:LQ, 8pv1:LQ, 8pv2:LQ, 8pv3:LQ, 8pv4:LQ, 8pv5:LQ, 8pv6:LQ, 8pv7:LQ, 8pv8:LQ, 8pvk:LQ, 8pvl:LQ, 7z3n:LQ, 7z3o:LQ
13 4v8p:BN 180 181 0.5241 0.5444 0.5414 3.00e-61 4v8p:CN, 4v8p:EN, 4v8p:GN
14 8aaf:D 185 173 0.5401 0.5459 0.5838 5.57e-61 8agt:D, 8agu:D, 8agv:D, 8agw:D, 8agx:D, 8agz:D, 5apn:Q, 5apo:Q, 7azy:m, 7b7d:Lm, 8bip:LQ, 8bjq:LQ, 8bn3:M8, 8bqd:BB, 8bqx:BB, 7bt6:Q, 7btb:Q, 6c0f:Q, 6cb1:Q, 8ccs:C, 8cdl:C, 8cdr:C, 8ceh:C, 8cf5:C, 8cg8:C, 8cgn:C, 8civ:C, 8cku:C, 8cmj:C, 5dat:M8, 5dat:m8, 5dc3:M8, 5dc3:m8, 5dge:M8, 5dge:m8, 5dgf:M8, 5dgf:m8, 5dgv:M8, 5dgv:m8, 8e5t:Q, 6elz:Q, 6em1:Q, 6em3:Q, 6em4:Q, 6em5:Q, 8eub:AQ, 8evp:AQ, 8evq:AQ, 8evr:AQ, 8evs:AQ, 8evt:AQ, 8ewb:AQ, 8ewc:AQ, 5fci:M8, 5fci:m8, 5fcj:M8, 5fcj:m8, 6ft6:Q, 5gak:S, 6gq1:Q, 6gqb:Q, 6gqv:Q, 5h4p:Q, 6hd7:S, 8hfr:Qk, 6hhq:y, 6hhq:CS, 5i4l:M8, 5i4l:m8, 6i7o:BB, 6i7o:YB, 5it7:QQ, 3j6x:58, 3j6y:58, 3j77:68, 3j78:68, 3jct:Q, 5jcs:Q, 5juo:V, 5jup:V, 5jus:V, 5jut:V, 5juu:V, 8k2d:LQ, 8k82:LQ, 5lyb:M8, 5lyb:m8, 5m1j:Q5, 6m62:Q, 5mc6:BB, 5mei:y, 5mei:CS, 7mpi:AQ, 7mpj:AQ, 6n8j:Q, 6n8k:Q, 6n8l:Q, 6n8m:d, 6n8n:d, 6n8o:d, 7n8b:AQ, 7nac:Q, 5ndg:M8, 5ndg:m8, 5ndv:M8, 5ndv:m8, 5ndw:M8, 5ndw:m8, 7nrc:LS, 7nrd:LS, 5obm:M8, 5obm:m8, 7of1:Q, 7oh3:Q, 7ohp:Q, 7ohq:Q, 7ohr:Q, 7ohs:Q, 7ohu:Q, 7ohv:Q, 7ohw:Q, 7ohx:Q, 7ohy:Q, 6oig:Q, 5on6:y, 5on6:CS, 7osa:eL18, 7osm:eL18, 8p8m:QP, 8p8n:QP, 8p8u:QP, 8pfr:QP, 6q8y:BB, 6qik:Q, 6qt0:Q, 6qtz:Q, 7r7a:Q, 6r84:S, 6r86:S, 6r87:S, 6ri5:Q, 7rr5:LQ, 6rzz:Q, 6s05:Q, 6s47:AS, 6snt:w, 6sv4:BB, 6sv4:YB, 6sv4:ZB, 6t4q:LQ, 5t62:d, 5t6r:d, 6t7i:LQ, 6t7t:LQ, 6t83:Qy, 6t83:B, 5tbw:y, 5tbw:CS, 6tb3:BB, 5tga:M8, 5tga:m8, 5tgm:M8, 5tgm:m8, 6tnu:BB, 7too:AL18, 7top:AL18, 7u0h:Q, 4u3m:M8, 4u3m:m8, 4u3n:M8, 4u3n:m8, 4u3u:M8, 4u3u:m8, 4u4n:M8, 4u4n:m8, 4u4o:M8, 4u4o:m8, 4u4q:M8, 4u4q:m8, 4u4r:M8, 4u4r:m8, 4u4u:M8, 4u4u:m8, 4u4y:M8, 4u4y:m8, 4u4z:M8, 4u4z:m8, 4u50:M8, 4u50:m8, 4u51:M8, 4u51:m8, 4u52:M8, 4u52:m8, 4u53:M8, 4u53:m8, 4u55:M8, 4u55:m8, 4u56:M8, 4u56:m8, 4u6f:M8, 4u6f:m8, 7ug6:Q, 7uoo:Q, 7uqb:Q, 7uqz:Q, 6uz7:AQ, 7v08:Q, 4v4b:BO, 4v6i:BR, 4v7f:Q, 4v7h:BO, 4v7r:BR, 4v7r:DR, 4v88:BQ, 4v88:DQ, 4v8t:Q, 4v8y:BQ, 4v8z:BQ, 8v83:Q, 8v84:Q, 8v87:Q, 4v91:Q, 6woo:Q, 6xiq:Q, 6xir:Q, 8y0u:LQ, 6ylg:Q, 6ylh:Q, 6ylx:Q, 6yly:Q, 5z3g:U, 7z34:Q, 6z6j:LQ, 6z6k:LQ, 7zpq:BP, 7zrs:BP, 7zs5:BR, 7zuw:BP, 7zux:EP, 7zw0:LT
15 5xy3:Q 185 186 0.5401 0.5459 0.5430 4.29e-59
16 8c3a:y 185 172 0.4973 0.5027 0.5407 5.05e-59 8c3a:BL, 8cq7:y, 8cq7:BL, 8cqw:y, 8cqw:BL, 8cre:y, 8cre:BL, 8oeq:y, 8oeq:BL, 7pzy:y, 7q08:y, 7q0f:y, 7q0p:y, 7q0r:y, 8q5i:y
17 4v8m:BI 192 187 0.4759 0.4635 0.4759 1.18e-52 8ova:BI, 8ove:BI
18 5t5h:I 192 179 0.4652 0.4531 0.4860 1.05e-51
19 8fru:Q 179 178 0.4439 0.4637 0.4663 1.60e-47 8br8:LR, 8brm:LR, 8bsi:LR, 8bsj:LR, 8btd:LR, 8btr:LR, 7pwg:Q, 7pwo:Q2
20 8a98:P 197 193 0.5080 0.4822 0.4922 9.47e-47 8a3w:P, 6az3:P, 3jcs:P, 8ovj:P, 8rxh:LP, 8rxx:LP, 5t2a:I
21 6zj3:Le 192 185 0.4545 0.4427 0.4595 2.92e-45
22 6zu5:LQ0 176 163 0.3422 0.3636 0.3926 2.60e-28
23 8p5d:LQ0 182 159 0.2941 0.3022 0.3459 3.40e-25 8p60:LQ0, 8p60:KQ0, 7qca:LQ0
24 6rm3:LQ0 184 173 0.2941 0.2989 0.3179 9.82e-21
25 7qep:M8 186 172 0.3048 0.3065 0.3314 6.35e-18
26 7oht:Q 85 121 0.2781 0.6118 0.4298 2.41e-17
27 6skf:BR 120 119 0.1711 0.2667 0.2689 1.62e-06 6skg:BR, 6th6:BR
28 4v4n:AP 120 116 0.1604 0.2500 0.2586 0.002 4v6u:BP
29 6vcf:E 432 64 0.0963 0.0417 0.2812 0.071 6vcg:E, 6vcg:F, 6vch:E, 6vch:F
30 2rhu:A 325 55 0.1016 0.0585 0.3455 0.34 6byb:A, 3oq5:A, 3oq5:C, 3p8h:A, 3p8h:B, 2pqw:A, 2rhi:A, 2rhx:A, 2rhy:A, 2rje:A, 2rje:B, 2rjf:A, 2rjf:C, 3uwn:A
31 8snh:G 304 30 0.0535 0.0329 0.3333 4.2
32 7ojn:L 2010 74 0.1390 0.0129 0.3514 5.1 5j1n:A, 5j1p:A, 4miw:A, 7oe7:L
33 5fb3:F 337 66 0.1070 0.0593 0.3030 8.3 5fb3:A, 5fb3:B, 5fb3:C, 5fb3:D, 5fb3:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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