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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GTYRKRFNEKARSGHMAKLKELKRIRNKQFTRSKVSRLKKKRLDKFIEHQLKREERKTIIGKLQDYKAYVPINENSTRKA
FYVEVSRSDEIQKARIQLPVFGEEHKIMEAIHHNDVVIICGETGSGKTTQVPQFLYEAGFGAEDSPDYPGMVGITQPRRV
AAVSMAERVANELGDHGHKVGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFKLTKYSSIIIDEAHERNINTDILIGMLS
RCVRLRAKLHKENPIEHKKLKLIIMSATLRVSDFSENKTLFPIAPPVLQVDQFPVSIHFNRRTAFNYTDEAFRKTCKIHQ
KLPPGAILVFLTGQQEITHMVKRLRKEEGQTANDPLYVLPLYSLLPTKEQMRVFQKPPQGSRLCIVATNVAETSLTIPGV
RYVVDSGRSKERKYNESNGVQSFEVGWVSKASANQRSGRAGRTGPGHCYRLYSSAVFEHDFEQEILRMPVESIVLQMKSM
AIHNIINFPFPTPPDRVALSKAIQLLQYLGALDNKEMITEDGKKMSLFPLSPRFSKMLLVSDEKACLPYIVAIVSALSVK
FYKSRSQFSKLDKFSDVFRLLSVVSAMDYVPKEQKEIFMKKNFLRGKLMEEIVKLRKQLMYIIKSNTSKENIAVVIRNEV
IQIKLLKQMICAGFVDHVAVRADVLFPDDAKITNRTSIINIPYIPVLATRTPNIEDCFVYIHPTSILNNLGEMPPKYMLY
YSLHLGGNNKTRMNTLCDIASTPLANIARKGLLLTYSKPLGLKTVNLSPTERYCYVVPRFGKIGWDLNPIAVHQKKQKGQ
WTVIKFI

The query sequence (length=807) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7aju:JD 811 811 1.0000 0.9951 0.9951 0.0 6zqd:JD, 6zqe:JD, 6zqf:JD
2 6zqg:JD 829 850 0.9542 0.9288 0.9059 0.0
3 6h57:A 795 787 0.8971 0.9107 0.9199 0.0
4 7d63:RZ 839 502 0.5700 0.5483 0.9163 0.0 7d4i:RZ, 7d5t:RZ, 7mqj:A
5 7d63:RZ 839 270 0.3321 0.3194 0.9926 0.0 7d4i:RZ, 7d5t:RZ, 7mqj:A
6 7mqa:NS 914 755 0.4275 0.3775 0.4570 0.0 6o16:A, 6o16:B
7 8cnt:A 620 668 0.3123 0.4065 0.3772 1.08e-126
8 6i3p:C 630 653 0.3061 0.3921 0.3783 3.85e-122 6i3p:A, 6i3p:B, 6i3p:D, 6qic:A, 6qic:B, 6qic:C, 6qic:D
9 8i0s:X 786 689 0.3024 0.3104 0.3541 1.66e-119 8i0t:X, 8i0u:X, 8i0v:X
10 8c6j:V 934 665 0.2986 0.2580 0.3624 9.37e-119 6hys:A, 6hys:B, 6hys:C, 6hys:D, 6hyt:A, 6hyt:B, 6hyt:C, 6hyt:D, 6hyu:A
11 7qtt:N 792 687 0.3011 0.3068 0.3537 5.45e-118 8ch6:N
12 6bk8:P 653 552 0.2689 0.3323 0.3931 1.81e-117 6exn:V, 5mq0:V
13 6rm8:A 655 659 0.2800 0.3450 0.3429 1.83e-111 6fa5:A, 6faa:A, 6fac:A, 6rm9:A, 6rma:A, 6rmb:A, 6rmc:A, 6rmc:B, 6zm2:A
14 5d0u:A 705 607 0.2850 0.3262 0.3789 3.43e-109 5lta:A, 5ltj:A, 5ltk:A, 6qid:A, 6qie:A
15 7b9v:Q 624 655 0.2999 0.3878 0.3695 7.71e-108
16 8ro1:DX 682 692 0.2986 0.3534 0.3483 4.73e-107
17 3kx2:B 755 487 0.2528 0.2702 0.4189 9.86e-106 5i8q:A, 5i8q:B, 5jpt:A, 5jpt:B, 3kx2:A, 2xau:A, 2xau:B, 5y88:W
18 6sh6:A 681 693 0.2949 0.3495 0.3434 3.11e-105 8ejm:A, 8ro2:DX, 5xdr:A
19 6hyu:C 585 649 0.2862 0.3949 0.3559 9.33e-105
20 7dcp:x 670 672 0.3011 0.3627 0.3616 7.90e-104 7dco:x, 7dd3:x
21 5gm6:Y 598 474 0.2466 0.3328 0.4198 8.92e-103
22 8po7:A 594 481 0.2280 0.3098 0.3825 3.52e-91
23 6zww:C 749 597 0.2466 0.2657 0.3333 3.77e-89 8po7:B, 8po8:A, 8po8:B, 6zww:A, 6zww:E, 6zww:G
24 5n9d:B 866 716 0.2714 0.2529 0.3059 6.87e-79 5n8r:A, 5n8r:B, 5n8s:A, 5n8s:B, 5n8u:A, 5n8u:B, 5n8z:A, 5n8z:B, 5n90:A, 5n90:B, 5n94:A, 5n94:B, 5n96:A, 5n96:B, 5n98:A, 5n98:B, 5n9a:A, 5n9a:B, 5n9d:A, 5n9e:A, 5n9e:B, 5n9f:A, 5n9f:B
25 5vhe:A 871 541 0.2218 0.2055 0.3309 8.96e-74 6up3:A, 6up4:A, 5vhc:D, 5vhd:D
26 8szq:A 861 550 0.2317 0.2172 0.3400 4.11e-68 3llm:A, 3llm:B, 8szp:A, 8szp:B, 8szr:A, 8szs:A
27 8pjb:A 962 569 0.2181 0.1830 0.3093 1.60e-62 8b9g:A, 8b9k:A, 8pjj:A
28 5aor:A 1009 584 0.2181 0.1744 0.3014 1.36e-60 5aor:B, 8b9i:A, 8b9j:A
29 6heg:A 783 448 0.1710 0.1762 0.3080 2.66e-46
30 6l5n:A 377 128 0.0434 0.0928 0.2734 0.024 6l5m:A, 6l5m:B, 6l5m:C, 6l5m:D, 6l5m:E, 6l5n:B, 6l5o:A
31 5elx:A 391 335 0.0892 0.1841 0.2149 0.026 3peu:A, 3pev:A, 3pew:A, 3pey:A, 3rrm:A, 3rrn:A
32 8buu:9 573 134 0.0434 0.0611 0.2612 0.064
33 2vso:A 366 196 0.0471 0.1038 0.1939 0.097 1fuk:A, 2vso:B, 2vsx:A, 2vsx:B
34 8as8:A 597 124 0.0446 0.0603 0.2903 0.11 8as8:B, 8bfn:A, 8bfn:B, 8bfn:F, 8bfn:G
35 8q72:A 750 124 0.0446 0.0480 0.2903 0.13 8q72:B, 8q72:F, 8q72:G
36 6b4i:F 426 136 0.0335 0.0634 0.1985 1.2 6b4i:E, 6b4j:E, 6b4j:F, 6b4k:A, 6b4k:B, 3ews:A, 3ews:B, 3fht:A, 3fht:B, 3fmo:B, 3fmp:B, 3fmp:D, 3g0h:A
37 3wqb:A 597 162 0.0434 0.0586 0.2160 1.2 3hjr:A
38 8arp:C 445 119 0.0372 0.0674 0.2521 1.5 8arp:A, 8arp:B, 8arp:D, 8arp:E, 8arp:F
39 8y6o:I 597 95 0.0297 0.0402 0.2526 1.6 8qp8:G, 6qw6:5X, 6qx9:5X, 8r08:G
40 3c7k:C 311 83 0.0310 0.0804 0.3012 2.5 3c7k:A
41 8wbx:B 467 39 0.0186 0.0321 0.3846 3.0
42 3jqp:D 269 90 0.0297 0.0892 0.2667 4.1 3jqp:A, 3jqp:B, 3jqp:C, 3jqp:E, 3jqp:F, 3jqq:A, 3jqq:B, 3jqq:C, 3jqq:D, 3jqq:E, 3jqq:F, 3jqr:A, 2ok7:A, 2ok7:B, 2ok7:C, 2ok7:D, 2ok7:E, 2ok7:F, 2ok8:A, 2ok8:B, 2ok8:C, 2ok8:D
43 1b87:A 181 28 0.0112 0.0497 0.3214 4.2 2a4n:A, 2a4n:B, 1n71:A, 1n71:B, 1n71:C, 1n71:D
44 8smc:C 1084 33 0.0161 0.0120 0.3939 4.3
45 7p48:6 510 111 0.0409 0.0647 0.2973 5.3
46 8esq:O 196 32 0.0136 0.0561 0.3438 6.7 8esr:O, 8etc:O, 8etg:O, 8eth:O, 8eti:O, 8etj:O, 8eug:O, 8eui:O, 8eup:O, 8euy:O, 8ev3:O
47 6ui4:A 692 89 0.0322 0.0376 0.2921 7.6
48 7v4r:A 437 284 0.0781 0.1442 0.2218 7.9
49 6qph:F 163 40 0.0161 0.0798 0.3250 9.0 6rhz:F, 6sl5:F, 6yxr:F
50 6yle:B 415 25 0.0124 0.0241 0.4000 9.4
51 8e2l:C 461 56 0.0186 0.0325 0.2679 9.6 8e2l:A, 8e2l:B, 8e2l:D, 8e2l:E, 8e2l:F
52 6bge:A 323 19 0.0136 0.0341 0.5789 9.6 6bge:B, 1g6o:A, 1g6o:B, 1nly:A, 1nly:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218