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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKER
ASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEK
AGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLAR
HLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAM
VKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLL
KPYESVMKVKAELCL

The query sequence (length=415) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5nx9:D 477 379 0.9084 0.7904 0.9947 0.0 2j91:A, 2j91:D, 2j91:B, 2j91:C, 5nx9:A, 5nx9:B, 5nxa:A, 5nxa:B, 5nxa:D, 5nxa:E, 5nxa:G, 5nxa:H, 5nxa:F, 2vd6:A, 2vd6:D, 2vd6:B, 2vd6:C
2 5nx9:D 477 47 0.0964 0.0839 0.8511 2.59e-21 2j91:A, 2j91:D, 2j91:B, 2j91:C, 5nx9:A, 5nx9:B, 5nxa:A, 5nxa:B, 5nxa:D, 5nxa:E, 5nxa:G, 5nxa:H, 5nxa:F, 2vd6:A, 2vd6:D, 2vd6:B, 2vd6:C
3 5nx9:C 441 365 0.8241 0.7755 0.9370 0.0
4 5nx9:C 441 46 0.0940 0.0884 0.8478 1.66e-20
5 5nxa:C 418 375 0.7687 0.7632 0.8507 0.0
6 5nxa:C 418 46 0.0940 0.0933 0.8478 1.46e-20
7 5vkw:B 469 366 0.5976 0.5288 0.6776 9.19e-180
8 5vkw:B 469 100 0.0843 0.0746 0.3500 9.13e-08
9 5eyt:A 472 379 0.4916 0.4322 0.5383 6.11e-138
10 2x75:A 427 352 0.2265 0.2201 0.2670 2.27e-33
11 2qga:C 455 350 0.2048 0.1868 0.2429 2.32e-12 2qga:B
12 4eei:B 423 334 0.1614 0.1584 0.2006 2.02e-10 4eei:A, 5hw2:A, 5hw2:C
13 4efc:A 452 246 0.1518 0.1394 0.2561 1.86e-08 4efc:B
14 3gzh:A 469 235 0.1277 0.1130 0.2255 2.85e-05 2ptq:A, 2ptq:B, 2ptr:A, 2ptr:B
15 1fuo:A 456 191 0.1205 0.1096 0.2618 4.38e-05 1fuo:B, 1fup:A, 1fup:B, 1fuq:A, 1fuq:B
16 7c18:B 464 198 0.1229 0.1099 0.2576 4.39e-05 7c18:A, 7c18:C, 7c18:D
17 7lub:B 462 292 0.1590 0.1429 0.2260 3.86e-04 7lub:A
18 5xnz:A 439 198 0.1373 0.1298 0.2879 0.001
19 6wng:A 466 123 0.0892 0.0794 0.3008 0.002 6wng:B, 6wng:D, 6wng:C
20 4mx2:B 439 170 0.1060 0.1002 0.2588 0.014 4mx2:A, 4mx2:C, 4mx2:D, 4mx2:E, 4mx2:F, 4mx2:G, 4mx2:H
21 3r6v:G 463 173 0.1060 0.0950 0.2543 0.027 3r6q:A, 3r6q:D, 3r6q:E, 3r6q:H, 3r6v:A, 3r6v:B, 3r6v:C, 3r6v:D, 3r6v:E, 3r6v:F, 3r6v:H, 3r6y:F
22 7t29:A 453 116 0.0699 0.0640 0.2500 0.027
23 3oce:A 461 176 0.1060 0.0954 0.2500 0.37 3oce:B, 3oce:C, 3oce:D
24 8hub:A 388 39 0.0313 0.0335 0.3333 0.63
25 4hor:A 482 109 0.0530 0.0456 0.2018 0.94 4hos:A, 4hot:A
26 5bof:A 434 127 0.0819 0.0783 0.2677 1.1 5boe:A, 5boe:B, 5bof:B
27 2oba:B 121 55 0.0482 0.1653 0.3636 2.5 2oba:A, 2oba:C, 2oba:D, 2oba:E, 2oba:F
28 6dbb:A 504 98 0.0747 0.0615 0.3163 4.5 6dbb:B, 6dbb:C
29 7kaa:A 152 36 0.0337 0.0921 0.3889 5.6
30 5jj2:A 211 54 0.0458 0.0900 0.3519 6.1
31 9em9:A 512 75 0.0530 0.0430 0.2933 6.6 9em9:B
32 1gl4:A 273 29 0.0265 0.0403 0.3793 7.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218