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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GSMEGILDFSNDLDIALLDQVVSTFYQGSGVQQKQAQEILTKFQDNPDAWQKADQILQFSTNPQSKFIALSILDKLITRK
WKLLPNDHRIGIRNFVVGMIISMCQDDEVFKTQKNLINKSDLTLVQILKQEWPQNWPEFIPELIGSSSSSVNVCENNMIV
LKLLSEEVFDFSAEQMTQAKALHLKNSMSKEFEQIFKLCFQVLEQGSSSSLIVATLESLLRYLHWIPYRYIYETNILELL
STKFMTSPDTRAITLKCLTEVSNLKIPQDNDLIKRQTVLFFQNTLQQIATSVMPVTADLKATYANANGNDQSFLQDLAMF
LTTYLARNRALLESDESLRELLLNAHQYLIQLSKIEERELFKTTLDYWHNLVADLFYEPLKKHIYEEICSQLRLVIIENM
VRPEEVLVVENEIVRKESDTIQLYKSEREVLVYLTHLNVIDTEEIMISKLARQIDGSEWSWHNINTLSWAIGSISGTMSE
DTEKRFVVTVIKDLLGLCEQKRGKDNKAVVASDIMYVVGQYPRFLKAHWNFLRTVILKLFEFMHETHEGVQDMACDTFIK
IVQKCKYHFVIQQPRESEPFIQTIIRDIQKTTADLQPQQVHTFYKACGIIISEERSVAERNRLLSDLMQLPNMAWDTIVE
QSTANPTLLLDSETVKIIANIIKTNVAVCTSMGADFYPQLGHIYYNMLQLYRAVSSMISAQVAAEGLIATKTPKVRGLRT
IKKEILKLVETYISKARNLDDVVKVLVEPLLNAVLEDYMNNVPDARDAEVLNCMTTVVEKVGHMIPQGVILILQSVFECT
LDMINKDFTEYPEHRVEFYKLLKVINEKSFAAFLELPPAAFKLFVDAICWAFKHNNRDVEVNGLQIALDLVKNIERMGNV
PFANEFHKNYFFIFVSETFFVLTDSDHKSGFSKQALLLMKLISLVYDNKISVPLYQVPQGTSNQVYLSQYLANMLSNAFP
HLTSEQIASFLSALTKQCKDLVVFKGTLRDFLVQIKEVGGDPTDYLFA

The query sequence (length=1008) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4gpt:C 1017 1017 0.9960 0.9872 0.9872 0.0 4gmx:C, 4hat:C, 4hau:C, 4hav:C, 4haw:C, 4hax:C, 4hay:C, 4haz:C, 4hb0:C, 4hb4:C, 5jlj:C, 7l5e:C, 6lq9:C, 5uwh:C, 5uwi:C, 5uwq:C, 5uwr:C, 5uwt:C, 5uww:C, 4wvf:C, 3wyg:C, 6xjp:C, 6xjr:C, 6xjs:C, 6xjt:C, 6xju:C, 5xoj:C, 5ysu:C, 5zpu:C
2 5uwu:C 998 1011 0.9861 0.9960 0.9832 0.0 6a38:C, 6a3a:C, 6a3b:C, 6a3c:C, 6a3e:C, 6cit:C, 7cnd:C, 5dh9:C, 5dha:C, 5dhf:C, 5di9:C, 5dif:C, 8hq3:C, 8hq4:C, 8hq5:C, 8hq6:C, 8huf:C, 8hug:C, 8itv:C, 6kft:C, 6m60:C, 6m6x:C, 5uwj:C, 5uwo:C, 5uwp:C, 5uws:C, 6x2p:C, 6x2r:C, 6x2s:C, 6x2u:C, 6x2v:C, 6x2w:C, 6x2x:C, 6x2y:C, 7ypz:C
3 6tvo:A 1011 1010 0.4841 0.4827 0.4832 0.0 2l1l:B
4 5yu6:C 1073 188 0.0367 0.0345 0.1968 1.04e-06 3a6p:A, 3a6p:F, 5yu6:A
5 5goe:A 384 144 0.0298 0.0781 0.2083 1.7 5gns:A, 5gnt:A
6 5anr:A 245 49 0.0179 0.0735 0.3673 2.4
7 8cmk:A 913 100 0.0248 0.0274 0.2500 2.5 8cmk:B, 6gx9:A, 6gx9:B
8 7d63:AE 1534 102 0.0258 0.0169 0.2549 4.1 7d5s:AE, 6ke6:AE, 6lqp:AE, 6lqq:AE, 6lqr:AE, 6lqs:AE, 6lqt:AE, 6lqu:AE, 6lqv:AE, 7suk:LM, 5wlc:LM
9 2yev:B 319 90 0.0208 0.0658 0.2333 4.4 2yev:E
10 8rd8:E9 199 89 0.0238 0.1206 0.2697 5.4 8rdv:E9, 8rdw:E9
11 5yvg:A 830 65 0.0218 0.0265 0.3385 5.6 2h4m:B, 2ot8:B, 5yvh:A
12 3i5o:A 582 81 0.0228 0.0395 0.2840 7.6 3i5o:B, 4jsd:A, 4jso:A, 2o7i:A
13 1keq:A 238 100 0.0228 0.0966 0.2300 8.1 1dmx:A, 1dmx:B, 1dmy:A, 1dmy:B, 1keq:B, 1urt:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218