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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GSHMSRSVYGTTLEAITKKSLYDLSIRCHRCQRPLGPEEKQKLVDEKKRFHEIAGRWTGQCANCWQRTRQRNETQV

The query sequence (length=76) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2m3l:A 76 76 1.0000 1.0000 1.0000 9.55e-54
2 6slm:A 539 70 0.6053 0.0853 0.6571 1.02e-27
3 7uaj:B 512 62 0.5000 0.0742 0.6129 2.26e-22 2fk4:A, 8gcr:A, 4giz:C, 4giz:D, 8jrn:D, 8jrn:B, 8jro:D, 8jro:B, 8jrp:B, 8jrp:D, 8jrq:B, 8jrq:D, 8jrr:B, 8jrr:D, 8r1f:B, 8r1g:B, 8r1g:E, 6siv:B, 6sja:B, 7uaj:A, 7uaj:C, 7uaj:D, 4xr8:F
4 4xr8:H 151 74 0.5658 0.2848 0.5811 1.16e-21 2ljx:A, 2ljy:A, 2ljy:B, 2ljz:A
5 6sjv:A 529 62 0.4737 0.0681 0.5806 3.72e-21 6sqc:A
6 6smv:A 525 57 0.2105 0.0305 0.2807 5.24e-05
7 7r78:A 1880 62 0.2105 0.0085 0.2581 1.3
8 7t02:A 1752 62 0.2105 0.0091 0.2581 1.4
9 7r76:A 1834 62 0.2105 0.0087 0.2581 1.5 7r77:A
10 5gak:q 154 50 0.1842 0.0909 0.2800 2.9 8aaf:v, 8agt:v, 8agu:v, 8agv:v, 8agx:v, 8agz:v, 8bn3:eI, 5dat:f, 5dc3:f, 5dge:f, 5dgf:f, 8k2d:CE, 5mc6:BT, 7nrc:Ls, 7rr5:5, 6tnu:eI, 8y0u:5
11 6hyu:C 585 39 0.1842 0.0239 0.3590 4.3
12 3czk:A 618 31 0.1579 0.0194 0.3871 4.4 3czg:A, 3czl:A
13 8c6j:V 934 39 0.1842 0.0150 0.3590 5.4 6hys:A, 6hys:B, 6hys:C, 6hys:D, 6hyt:A, 6hyt:B, 6hyt:C, 6hyt:D, 6hyu:A
14 1x4k:A 72 30 0.1316 0.1389 0.3333 7.1
15 8uu9:V 93 28 0.1316 0.1075 0.3571 7.7 8a57:W, 8a5i:W, 8a63:W, 7nhn:W, 8uu4:V, 8uu5:V, 8uu6:V, 8uu7:V, 8uu8:V, 8uua:V
16 8sr8:A 1353 34 0.1711 0.0096 0.3824 8.7 8sr8:B, 8sr8:C, 8sr8:D, 8sr9:A, 8sr9:B, 8sr9:C, 8sr9:D, 8sra:A, 8sra:B, 8sra:C, 8sra:D, 8srb:A, 8srb:B, 8srb:C, 8srb:D
17 8sre:A 1377 34 0.1711 0.0094 0.3824 8.7 8sr7:A, 8sr7:B, 8sr7:C, 8sr7:D, 8src:A, 8src:B, 8src:C, 8src:D, 8srd:A, 8srd:B, 8srd:C, 8srd:D, 8sre:B, 8sre:D, 8sre:C, 8srf:A, 8srf:B, 8srf:C, 8srf:D, 8srg:A, 8srg:B, 8srg:C, 8srg:D, 8srh:A, 8srh:B, 8srh:C, 8srh:D, 8sri:A, 8sri:B, 8sri:C, 8sri:D, 8srj:A, 8srj:B, 8srj:D, 8srj:C, 8srk:A, 8srk:B, 8srk:C, 8srk:D
18 5a9z:BS 88 40 0.1842 0.1591 0.3500 9.2 5aa0:BS, 4aqy:O, 7azo:S15A, 7azo:S15B, 7azs:S15A, 7azs:S15B, 9b00:1o, 9b00:2o, 4b3m:O, 4b3r:O, 4b3s:O, 4b3t:O, 6b4v:XA, 6b4v:BD, 6boh:YA, 6boh:DD, 6bok:WA, 6bok:ZC, 5br8:O, 6buw:QO, 6buw:XO, 6bz6:QO, 6bz6:XO, 6bz7:QO, 6bz7:XO, 6bz8:QO, 6bz8:XO, 6c5l:AO, 6c5l:CO, 6cae:1o, 6cae:2o, 6cao:O, 6cap:O, 6caq:O, 6car:O, 6cas:O, 6cfj:1o, 6cfj:2o, 6cfk:1o, 6cfk:2o, 6cfl:1o, 6cfl:2o, 8cvj:1o, 8cvj:2o, 8cvk:1o, 8cvk:2o, 8cvl:1o, 8cvl:2o, 5czp:XO, 5czp:QO, 6czr:1o, 6czr:2o, 5d8b:PA, 5d8b:LC, 5dfe:XO, 5dfe:QO, 1dk1:A, 5dox:1o, 5dox:2o, 5doy:1o, 5doy:2o, 4dr1:O, 4dr2:O, 4dr3:O, 4dr4:O, 4dr5:O, 4dr6:O, 4dr7:O, 6dti:O, 4duy:O, 4duz:O, 7dug:O, 7duh:O, 7dui:O, 7duj:O, 7duk:O, 7dul:O, 4dv0:O, 4dv1:O, 4dv2:O, 4dv3:O, 4dv4:O, 4dv5:O, 4dv6:O, 4dv7:O, 2e5l:O, 5e7k:6I, 5e7k:6A, 5e81:6I, 5e81:6A, 8ekb:1o, 8ekb:2o, 5el4:6I, 5el4:6A, 5el5:6I, 5el5:6A, 5el6:6I, 5el6:6A, 5el7:6I, 5el7:6A, 8ev6:1o, 8ev6:2o, 8ev7:1o, 8ev7:2o, 2f4v:O, 1f7y:A, 5f8k:1o, 5f8k:2o, 8fc1:1o, 8fc1:2o, 8fc2:1o, 8fc2:2o, 8fc3:1o, 8fc3:2o, 8fc4:1o, 8fc4:2o, 8fc5:1o, 8fc5:2o, 8fc6:1o, 8fc6:2o, 5fdu:1o, 5fdu:2o, 5fdv:1o, 5fdv:2o, 1fjg:O, 1fka:O, 6fkr:1o, 6fkr:2o, 8fom:QO, 8fom:XO, 8fon:QO, 8fon:XO, 1g1x:B, 1g1x:G, 8g29:1o, 8g29:2o, 8g2a:1o, 8g2a:2o, 8g2b:1o, 8g2b:2o, 8g2c:1o, 8g2c:2o, 8g2d:1o, 8g2d:2o, 4gkj:O, 4gkk:O, 6gsj:6I, 6gsj:6A, 6gsk:6I, 6gsk:6A, 6gsl:6I, 6gsl:6A, 6gzq:O2, 6gzx:O3, 6gzx:O4, 6gzz:O3, 6gzz:O4, 5hau:1o, 5hau:2o, 5hcp:1o, 5hcp:2o, 5hcq:1o, 5hcq:2o, 5hcr:1o, 5hcr:2o, 5hd1:1o, 5hd1:2o, 2hhh:O, 1hnw:O, 1hnx:O, 1hnz:O, 1hr0:O, 1i94:O, 1i97:O, 1ibk:O, 1ibl:O, 1ibm:O, 5ib7:6I, 5ib7:6A, 5ib8:6I, 5ib8:6A, 5ibb:6I, 5ibb:6A, 5imq:S, 5imr:S, 5iwa:O, 5j30:QO, 5j30:XO, 5j3c:QO, 5j3c:XO, 5j4b:1o, 5j4b:2o, 5j4c:1o, 5j4c:2o, 5j4d:XA, 5j4d:CD, 1j5e:O, 5j8b:o, 4ji0:O, 4ji1:O, 4ji2:O, 4ji3:O, 4ji4:O, 4ji5:O, 4ji6:O, 4ji7:O, 4ji8:O, 7jql:1o, 7jql:2o, 7jqm:1o, 7jqm:2o, 4jv5:O, 4jya:O, 4k0k:O, 4khp:O, 1kuq:A, 4kvb:O, 4l47:QO, 4l47:XO, 4l71:QO, 4l71:XO, 4lel:QO, 4lel:XO, 4lf4:O, 4lf5:O, 4lf6:O, 4lf7:O, 4lf8:O, 4lf9:O, 4lfa:O, 4lfb:O, 4lfc:O, 4lfz:QO, 4lfz:XO, 7lh5:AO, 7lh5:CO, 5lmn:O, 5lmo:O, 5lmp:O, 5lmq:O, 5lmr:O, 5lms:O, 5lmt:O, 5lmu:O, 5lmv:O, 4lnt:QO, 4lnt:XO, 4lsk:QO, 4lsk:XO, 4lt8:QO, 4lt8:XO, 7md7:1o, 7md7:2o, 6mkn:O, 6mpf:O, 6mpi:O, 6n1d:AS15, 6n1d:BS15, 1n32:O, 1n33:O, 1n34:O, 1n36:O, 6n9e:1o, 6n9e:2o, 6n9f:1o, 6n9f:2o, 5ndj:6I, 5ndj:6A, 5ndk:6I, 5ndk:6A, 6nd5:1o, 6nd5:2o, 6nd6:1o, 6nd6:2o, 6ndk:QO, 6ndk:XO, 6nsh:QO, 6nsh:XO, 6nta:QO, 6nta:XO, 6nuo:QO, 6nuo:XO, 6nwy:QO, 6nwy:XO, 4nxm:O, 4nxn:O, 6ny6:O, 6o3m:QO, 6o3m:XO, 6o97:1o, 6o97:2o, 6of1:1o, 6of1:2o, 6of6:QO, 6of6:XO, 6oj2:QO, 6oj2:XO, 6ope:QO, 6ope:XO, 6ord:QO, 6ord:XO, 6osi:QO, 6osi:XO, 3oto:O, 5ot7:N, 6otr:QO, 6otr:XO, 4ox9:O, 6oxa:QO, 6oxa:XO, 6oxi:QO, 6oxi:XO, 4p6f:QO, 4p6f:XO, 4p70:QO, 4p70:XO, 6q95:t, 6qnq:6I, 6qnq:6A, 6qnr:6I, 6qnr:6A, 7rq8:1o, 7rq8:2o, 7rq9:1o, 7rq9:2o, 7rqa:1o, 7rqa:2o, 7rqb:1o, 7rqb:2o, 7rqc:1o, 7rqc:2o, 7rqd:1o, 7rqd:2o, 7rqe:1o, 7rqe:2o, 3t1h:O, 3t1y:O, 8t8b:1o, 8t8b:2o, 8t8c:1o, 8t8c:2o, 4tua:QO, 4tua:XO, 4tub:QO, 4tub:XO, 4tuc:QO, 4tuc:XO, 4tud:QO, 4tud:XO, 4tue:QO, 4tue:XO, 7u2h:1o, 7u2h:2o, 7u2i:1o, 7u2i:2o, 7u2j:1o, 7u2j:2o, 6ucq:1o, 6ucq:2o, 8ud6:1o, 8ud6:2o, 8ud7:1o, 8ud7:2o, 8ud8:1o, 8ud8:2o, 6uo1:1o, 6uo1:2o, 5uq7:o, 5uq8:o, 2uu9:O, 2uua:O, 2uub:O, 2uuc:O, 8uvr:1o, 8uvr:2o, 8uvs:1o, 8uvs:2o, 2uxb:O, 2uxc:O, 2uxd:O, 7v2l:O, 7v2m:O, 7v2n:O, 7v2o:O, 7v2p:O, 7v2q:O, 4v49:AO, 4v4a:AO, 4v4g:AO, 4v4g:CO, 4v4g:EO, 4v4g:GO, 4v4g:IO, 4v4i:p, 4v4j:p, 4v4p:BR, 4v4r:AO, 4v4s:AO, 4v4t:AO, 4v4x:AR, 4v4y:AR, 4v4z:AR, 4v51:AO, 4v51:CO, 4v5a:AO, 4v5a:CO, 4v5c:AO, 4v5c:CO, 4v5d:AO, 4v5d:CO, 4v5e:AO, 4v5e:CO, 4v5f:AO, 4v5f:CO, 4v5g:AO, 4v5g:CO, 4v5j:AO, 4v5j:CO, 4v5k:AO, 4v5k:CO, 4v5l:AO, 4v5m:AO, 4v5n:AO, 4v5p:AO, 4v5p:CO, 4v5q:AO, 4v5q:CO, 4v5r:AO, 4v5r:CO, 4v5s:AO, 4v5s:CO, 4v5z:Ao, 4v63:AO, 4v63:CO, 4v67:AO, 4v67:CO, 4v68:AO, 4v6a:AO, 4v6a:CO, 4v6f:BR, 4v6f:CR, 4v6g:AR, 4v6g:CR, 4v7j:Ao, 4v7j:Bo, 4v7k:Ao, 4v7k:Bo, 4v7l:AO, 4v7l:CO, 4v7m:AO, 4v7m:CO, 4v7p:AO, 4v7p:DO, 4v7w:AO, 4v7w:CO, 4v7x:AO, 4v7x:CO, 4v7y:AO, 4v7y:CO, 4v7z:AO, 4v7z:CO, 4v83:AO, 4v83:CO, 4v84:AO, 4v84:CO, 4v87:BR, 4v87:CR, 4v8a:DO, 4v8a:CO, 4v8b:AR, 4v8b:CR, 4v8c:CR, 4v8c:DR, 4v8d:AR, 4v8d:CR, 4v8e:BR, 4v8e:DR, 4v8f:BR, 4v8f:CR, 4v8g:AO, 4v8g:CO, 4v8h:AO, 4v8h:CO, 4v8i:AO, 4v8i:CO, 4v8j:AO, 4v8j:CO, 4v8n:AO, 4v8n:CO, 4v8o:AO, 4v8q:BO, 4v8u:AO, 4v8u:CO, 4v8x:AO, 4v8x:CO, 5v8i:1o, 5v8i:2o, 4v90:AO, 4v95:AO, 4v95:CO, 4v97:AO, 4v97:CO, 4v9a:AR, 4v9a:CR, 4v9b:AR, 4v9b:CR, 4v9h:AO, 4v9i:AO, 4v9i:CO, 4v9j:AO, 4v9j:CO, 4v9k:AO, 4v9k:CO, 4v9l:AO, 4v9l:CO, 4v9m:AO, 4v9m:CO, 4v9n:AO, 4v9n:CO, 4v9q:BO, 4v9q:DO, 4v9r:AO, 4v9r:CO, 4v9s:AO, 4v9s:CO, 5vp2:1o, 5vp2:2o, 5vpo:QO, 5vpo:XO, 5vpp:QO, 5vpp:XO, 2vqe:O, 2vqf:O, 8vtu:1o, 8vtu:2o, 8vtv:1o, 8vtv:2o, 8vtw:1o, 8vtw:2o, 8vtx:1o, 8vtx:2o, 8vty:1o, 8vty:2o, 1vvj:QO, 1vvj:XO, 1vy4:AO, 1vy4:CO, 1vy5:AO, 1vy5:CO, 1vy6:AO, 1vy6:CO, 1vy7:AO, 1vy7:CO, 4w29:AO, 4w29:CO, 4w2e:o, 4w2f:AO, 4w2f:CO, 4w2g:AO, 4w2g:CO, 4w2h:AO, 4w2h:CO, 4w2i:AO, 4w2i:CO, 4w4g:QO, 4w4g:XO, 5w4k:1o, 5w4k:2o, 5wis:1o, 5wis:2o, 5wit:1o, 5wit:2o, 5wnp:O, 5wnq:O, 5wnr:O, 5wns:O, 5wnt:O, 5wnu:O, 5wnv:O, 4wpo:BO, 4wpo:DO, 4wq1:6I, 4wq1:6A, 4wqf:BO, 4wqf:DO, 4wqr:6I, 4wqr:6A, 4wqu:BO, 4wqu:DO, 4wqy:BO, 4wqy:DO, 4wr6:6I, 4wr6:6A, 4wra:6I, 4wra:6A, 4wro:6I, 4wsd:6I, 4wsd:6A, 4wsm:6I, 4wsm:6A, 4wt1:6I, 4wt1:6A, 4wt8:AO, 4wt8:BO, 4wu1:6I, 4wu1:6A, 4wzd:6I, 4wzd:6A, 4wzo:6I, 4wzo:6A, 4x62:O, 4x64:O, 4x65:O, 4x66:O, 4xej:AS15, 4xej:BS15, 6xhv:1o, 6xhv:2o, 6xhw:1o, 6xhw:2o, 6xhx:1o, 6xhx:2o, 6xhy:1o, 6xhy:2o, 1xmo:O, 1xmq:O, 1xnq:O, 1xnr:O, 6xqd:1o, 6xqd:2o, 6xqe:1o, 6xqe:2o, 4y4o:1o, 4y4o:2o, 4y4p:1o, 4y4p:2o, 4yhh:O, 4ypb:QO, 4ypb:XO, 4yy3:O, 4yzv:QO, 4yzv:XO, 4z3s:1o, 4z3s:2o, 4z8c:1o, 4z8c:2o, 4zer:1o, 4zer:2o, 5zlu:T, 2zm6:O, 4zsn:QO, 4zsn:XO

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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