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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GSHMRLNLGGAEVFLRAEGLEEAPGGVRLWGREVRVFPPFPAKGFFRHGWQSWSLAAWVDPAQAPTPLLPEARRPQADDP
FLLEAGAWWGSGVGALRGPDGRALLLGALDLGARVLGREDLLLGRYAGKGGAWFLAYGPEEEVFAAYARLLPRRLSGRPP
RVWCSWYSFYTRIGEDLLLRVLDEVAAFSFEVFQIDDGWQRALGDWEPNDRFPRGMAFLAERIRERGLRAGLWFAPFLVT
ADSPLFQKRPDWVLRDGEGRPVRAGFNWGRPLYALDAGNEEVVEWAADLVRKALAWGYDYLKLDFLYAAALPGAEGEARY
RKAMARLREAAGEAYLLFCGAPVLASLGLADGLRVGPDVAPYWDNEERSFWLADPTGPGLRNALRSTLHRLWLMENVHVD
PDVVYFRTRFNLLSPEEMRLQEALAHFTGFKATSDPPSWLLPEEKGRLEAFLAREVPVRRLGPYRFRVGEEEVDYAPLL

The query sequence (length=479) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6lck:A 479 479 1.0000 1.0000 1.0000 0.0 6lck:B, 6lck:C, 6lcl:A, 6lcl:C, 6lcl:E
2 5m1i:A 539 275 0.2067 0.1837 0.3600 1.32e-49 6gta:A, 6gvd:A, 6gwf:A, 6gwg:A, 6gx8:A, 5m0x:A, 5m12:A, 5m16:A
3 2xn2:A 729 178 0.1106 0.0727 0.2978 5.28e-17
4 6phv:A 721 177 0.1065 0.0707 0.2881 1.42e-14 6phw:A, 6phx:A, 6phy:A, 6pi0:A
5 2yfn:A 719 155 0.0960 0.0640 0.2968 2.41e-14 2yfo:A
6 4fns:A 718 155 0.1023 0.0682 0.3161 7.22e-14 4fns:B, 4fns:C, 4fns:D, 4fnt:C, 4fnt:B, 4fnt:A, 4fnt:D, 4fnu:A, 4fnu:B, 4fnu:C, 4fnu:D
7 8k7v:B 755 163 0.1044 0.0662 0.3067 1.01e-13 8k7v:A, 8k7v:C, 8k7v:D
8 1uas:A 362 243 0.1190 0.1575 0.2346 4.75e-06
9 2f2h:A 773 174 0.1023 0.0634 0.2816 1.33e-04 2f2h:B, 2f2h:C, 2f2h:D, 2f2h:E, 2f2h:F, 1xsk:A, 1xsk:B, 1xsk:C, 1xsk:E
10 1szn:A 417 103 0.0564 0.0647 0.2621 2.99e-04 1t0o:A
11 3a22:A 614 277 0.1315 0.1026 0.2274 0.001 3a22:B, 3a23:A, 3a23:B
12 7qqg:B 623 107 0.0564 0.0433 0.2523 0.002 7qqg:A, 7qqg:C, 7qqh:A, 7qqh:B, 7qqh:C, 7qqh:D
13 7qqg:D 496 107 0.0564 0.0544 0.2523 0.002
14 4do4:B 400 102 0.0605 0.0725 0.2843 0.022 4do4:A, 4do5:A, 4do5:B, 4do6:A, 4do6:B, 3h55:A, 3h55:B, 3igu:A, 3igu:B
15 5awp:A 596 239 0.1273 0.1023 0.2552 0.026 5awq:A
16 2x1i:A 497 126 0.0772 0.0744 0.2937 0.26
17 7paj:9 393 102 0.0668 0.0814 0.3137 1.1 7pak:9, 7pha:9, 7pi9:9, 7pip:9
18 1shc:A 195 63 0.0376 0.0923 0.2857 2.3 2l1c:A
19 3hg3:A 395 128 0.0710 0.0861 0.2656 2.6 3gxp:A, 3gxp:B, 3gxt:A, 3gxt:B, 3hg2:B, 3hg3:B, 3hg4:A, 3hg4:B, 3hg5:A, 3hg5:B, 6ibk:A, 6ibk:B, 6ibm:A, 6ibm:B, 6ibr:A, 6ibr:B, 6ibt:A, 6ibt:B, 8k7d:A, 8k7d:B, 8k7e:A, 8k7e:B, 8k7f:A, 8k7f:B, 8k7g:A, 8k7g:B, 8k7h:A, 8k7h:B, 8k7i:A, 8k7i:B, 8k7j:A, 8k7j:B, 8k7k:A, 8k7k:B, 8k7l:A, 8k7l:B, 3lxa:A, 3lxa:B, 4nxs:A, 4nxs:B, 1r47:A, 1r47:B, 3s5y:A, 3s5y:B, 3s5z:A, 3s5z:B, 3tv8:A, 3tv8:B
20 8cej:A 449 52 0.0355 0.0379 0.3269 2.6 8cej:B, 8cej:C, 8cej:D, 8cek:A, 8cek:B, 8cek:C, 8cek:D
21 1esw:A 500 70 0.0459 0.0440 0.3143 2.6 5jiw:A, 2owc:A, 2oww:A
22 4ymg:B 239 36 0.0271 0.0544 0.3611 3.7 4ymg:A, 4ymh:A, 4ymh:B, 4ymh:C, 4ymh:D
23 7exf:B 719 47 0.0334 0.0223 0.3404 5.5 7exf:A, 7exg:B, 7exg:A, 7exh:B, 7exh:A, 7exj:A, 7exj:B, 7exq:A, 7exq:B, 7exr:A, 7exr:B
24 3msd:A 330 79 0.0459 0.0667 0.2785 7.2 3msd:B, 3msg:A, 3msg:B, 3mua:A, 3mua:B, 3mui:A, 3mui:B
25 4xpq:A 670 38 0.0209 0.0149 0.2632 7.4 4xpp:A, 4xps:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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