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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GSHMAKTVILDHDGNKDDFVAMILLLSNPKKVNLIGCICTDADCFVENGFDVTGKIMCAMHRLIKTPLFPIGKSTATAVN
AFPTEWRFSAKNLDDMPFLNIVEDVALWEKLKPENEAHNGQQLLADLVMKSKEKVTVCVTGPLSNMAWCIEKYGEAFTSK
VEECVIMGGAVDVGGNVFLPTTDGSAEWNIYWDPPAAKKVLCCPNIRCVLFSLDATNTVPVRSVDVKGFGAQNQYLLSQM
VGTMWAMSTAYYAWDALTAAYILEPTIATLEPVALDVDVSKGKSEGRTPRAGKPCVHVARNPSKQMFHDLVFASTRVC

The query sequence (length=318) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4i72:A 328 328 1.0000 0.9695 0.9695 0.0 4i70:A, 4i71:A, 4i72:B, 4i73:A, 4i73:B, 4i73:C, 4i73:D, 4i74:A, 4i75:A, 4i75:B
2 2ff2:B 327 326 0.6730 0.6544 0.6564 6.86e-151 3b9g:A, 3b9g:B, 3epw:A, 3epw:B, 3epx:A, 3epx:B, 2ff1:A, 2ff1:B, 2ff2:A, 1hoz:A, 1hoz:B, 1hp0:A, 1hp0:B, 1kic:A, 1kic:B, 1kie:A, 1kie:B, 1r4f:A, 1r4f:B
3 2c40:A 302 310 0.3176 0.3344 0.3258 2.51e-41 2c40:B
4 3mkm:A 311 301 0.2421 0.2476 0.2558 2.26e-13 3b9x:A, 3b9x:B, 3b9x:D, 3mkm:B, 3mkm:C, 3mkm:D, 3mkn:A, 3mkn:B, 3mkn:C, 3mkn:D, 1q8f:A, 1q8f:B, 1q8f:C, 1q8f:D
5 3b9x:C 283 295 0.2358 0.2650 0.2542 1.11e-12
6 4wr2:A 308 295 0.2390 0.2468 0.2576 4.11e-12
7 6ba1:A 316 300 0.2484 0.2500 0.2633 6.01e-10 6ba1:B, 6ba1:C, 6ba1:D, 6ba1:E, 6ba1:F, 6ba1:G, 6ba1:H, 6ba1:I, 6ba1:J, 6ba1:K, 6ba1:L, 6ba1:M, 6ba1:N, 6ba1:O, 6ba1:P, 6ba1:Q, 6ba1:R
8 3g5i:A 305 206 0.1887 0.1967 0.2913 6.33e-10 3g5i:B, 3g5i:C, 3g5i:D, 1yoe:A
9 5mj7:A 322 214 0.1887 0.1863 0.2804 1.38e-09 5mj7:B
10 1ezr:A 312 194 0.1478 0.1506 0.2423 4.49e-09 8ctm:A, 8ctm:B, 8ctm:C, 8ctm:D, 1ezr:B, 1ezr:C, 1ezr:D
11 4kpn:A 318 151 0.1289 0.1289 0.2715 3.05e-08 4kpn:B, 4kpn:C, 4kpn:D, 4kpn:E, 4kpn:F, 4kpn:G, 4kpn:H
12 6ba0:A 312 335 0.2453 0.2500 0.2328 1.12e-07 6ba0:B, 6ba0:C, 6ba0:D
13 2mas:A 313 343 0.2673 0.2716 0.2478 2.27e-07 2mas:B, 2mas:C, 2mas:D
14 8qnd:A 297 183 0.1415 0.1515 0.2459 2.22e-06 8qnd:C, 8qnd:B, 8qnd:D
15 4kpo:A 317 198 0.1572 0.1577 0.2525 2.47e-06 4kpo:B, 6zk5:A, 6zk5:B
16 6zk3:A 319 189 0.1698 0.1693 0.2857 5.07e-06 6zk1:A, 6zk1:B, 6zk1:C, 6zk1:D, 6zk2:A, 6zk2:B, 6zk2:C, 6zk2:D, 6zk3:B, 6zk3:C, 6zk3:D, 6zk3:E, 6zk3:F, 6zk4:A, 6zk4:B, 6zk4:C, 6zk4:D
17 5tsq:A 312 336 0.2421 0.2468 0.2292 7.86e-06
18 8rih:B 333 253 0.1572 0.1502 0.1976 8.47e-04 8rih:A
19 3t8i:A 306 90 0.0912 0.0948 0.3222 0.38 3t8i:B, 3t8i:C, 3t8i:D
20 4b9p:A 166 90 0.0723 0.1386 0.2556 0.52
21 7dqx:C 160 80 0.0629 0.1250 0.2500 1.1 7dqx:F
22 3gvh:A 318 52 0.0503 0.0503 0.3077 2.4 3gvh:B, 3gvh:C, 3gvh:D, 3gvi:A, 3gvi:B, 3gvi:C, 3gvi:D, 3gvi:E, 3gvi:F
23 4ros:A 318 36 0.0440 0.0440 0.3889 3.3 5ujk:A
24 3wd6:A 242 112 0.0943 0.1240 0.2679 3.3 3wd6:B, 3wd6:C, 3wd6:D
25 8ppt:A 447 73 0.0723 0.0515 0.3151 8.1 6hmf:A, 6hmf:B, 5ihe:A, 5ihe:B, 8ppu:A, 8ppv:A, 6t8h:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218