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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GSEIFLASKRAAITYDTDPATGEPRAWLAPGGTGNVVAEQAGVLNISWIASADSEDDRRASALNPDGVTMELHSGREILV
RLIRHDPAVFRNVQNFMTANLMWAANNYGWDRWTQPSFGSDAREGWADFGRFTRDFADAILKSSAQSADPVYLVHNYQLV
GVPALLREQRPDAPILLFVHIPWPSADYWRILPKEIRTGILHGMLPATTIGFFADRWCRNFLESVADLLPDARIDREAMT
VEWRGHRTRLRTMPLGYSPLTLPQLPEGIEEWADGHRLVVHSGRTDPIKNAERAVRAFVLAARGGGLEKTRMLVRMNPNR
LYVPANADYVHRVETAVAEANAELGSDTVRIDNDNDVNHTIACFRRADLLIFNSTVDGQNLSTFEAPLVNERDADVILSE
TCGAAEVLGEYCRSVNPFDLVEQAEAISAALAAGPRQRAEAAARRRDAARPWTLEAWVQAQLDGLAADHAARTAT

The query sequence (length=475) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8iye:A 475 475 1.0000 1.0000 1.0000 0.0 4f96:B, 4f96:A, 4f97:A, 4f97:B, 4f9f:A, 4f9f:D, 4f9f:B, 4f9f:C, 4f9f:E, 4f9f:F, 8iye:B, 8iyf:A, 8iyf:B, 3t5t:A, 3t5t:B, 3t7d:A, 3t7d:B, 3vdn:B
2 8fhw:A 432 351 0.2084 0.2292 0.2821 1.95e-25 8fhw:B, 8fhw:C, 8fhw:D
3 6jbr:A 465 334 0.1937 0.1978 0.2754 4.49e-24 6jbr:B, 6jbr:D, 6jbr:F, 6jbr:H, 6jbr:K, 6jbr:M, 6jbr:O, 6jbw:A, 6jbw:B
4 5hvm:B 452 389 0.2084 0.2190 0.2545 2.89e-22 5hvm:A
5 5hvo:A 459 343 0.2042 0.2113 0.2828 1.38e-21 5hvo:B, 5hvo:C, 5hvo:D
6 5hut:A 469 371 0.1916 0.1940 0.2453 3.12e-21 5hut:B, 5huu:A, 5huu:B, 5huv:A, 5huv:B, 5hvl:A, 5hvl:B
7 5jio:A 467 369 0.2147 0.2184 0.2764 1.00e-18 5k41:A, 5k42:A, 5k44:A, 5k5c:A, 5l3k:A, 5l3k:B, 5l3k:C, 5l3k:D, 5l3k:E, 5l3k:F, 5l3k:G, 5l3k:H
8 2wtx:D 457 365 0.1726 0.1794 0.2247 3.44e-06 1gz5:A, 1gz5:B, 1gz5:C, 1gz5:D, 1uqt:A, 1uqt:B, 1uqu:A, 2wtx:A, 2wtx:B, 2wtx:C
9 5v0t:E 457 321 0.1642 0.1707 0.2430 9.90e-06 5v0t:A, 5v0t:B, 5v0t:C, 5v0t:D, 5v0t:F, 5v0t:G, 5v0t:H
10 5tvg:A 468 336 0.1642 0.1667 0.2321 3.26e-05 5tvg:B, 5tvg:C, 5tvg:D, 5tvg:E, 5tvg:F, 5tvg:G, 5tvg:H, 5uof:B
11 8snb:8K 322 65 0.0316 0.0466 0.2308 0.65
12 6euo:C 354 68 0.0400 0.0537 0.2794 0.77 6euo:A, 6euo:B, 6euo:D, 6eur:A, 6eur:C, 6eur:D, 6exf:A, 6exf:C, 6exf:D, 6exh:A, 6exh:B, 6exh:C, 6exh:D, 6f9p:A, 6f9p:C, 6f9p:D
13 6eur:B 328 68 0.0400 0.0579 0.2794 1.1 6exf:B
14 8kdb:A 2117 74 0.0442 0.0099 0.2838 2.0 8kdc:A
15 8buu:X 61 31 0.0274 0.2131 0.4194 4.9 7aqc:X, 7aqd:X, 7as8:b, 7as9:b, 6ha1:X, 6ha8:X, 6htq:W, 3j9w:B0, 5njt:u, 7o5b:v, 7ope:b, 8qcq:X, 7qgu:Y, 7qh4:Y, 8qpp:v, 7qv1:u, 7qv2:u, 7qv3:u, 8r55:v, 8s1p:X, 8s1u:X, 6tnn:u, 6tpq:u
16 8j07:8P 360 28 0.0232 0.0306 0.3929 5.0
17 8csp:8 326 69 0.0421 0.0613 0.2899 6.2 2c2n:A, 8csq:8, 8csr:8, 8css:8
18 8qlp:E 419 26 0.0211 0.0239 0.3846 9.6 8qlp:A, 8qlp:I, 8qlp:M

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218